{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T08:07:46Z","timestamp":1772179666559,"version":"3.50.1"},"reference-count":32,"publisher":"FapUNIFESP (SciELO)","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arq Bras Endocrinol Metab"],"published-print":{"date-parts":[[2011,8]]},"abstract":"<jats:p>OBJETIVOS: Avaliar o perfil epidemiol\u00f3gico e a evolu\u00e7\u00e3o de mulheres com diabetes melito gestacional (DMG), determinando fatores de risco para maior vigil\u00e2ncia. SUJEITOS E M\u00c9TODOS: Foram estudadas 924 gesta\u00e7\u00f5es de 916 pacientes, de 6 de novembro de 2001 a 21 de setembro de 2009. RESULTADOS: Foram encontrados fatores de risco para DMG em 95,1% dos casos. A preval\u00eancia de diabetes materno, paterno e em outros familiares foi de 24,3%, 9,4% e 24,7%, respectivamente. Os fatores preditivos para uso de insulina foram: glicemia de jejum (GJ) no rastreamento \u2265 85, GJ no Teste Oral de Toler\u00e2ncia \u00e0 Glicose (TOTG) \u2265 95, glicemia 2h ap\u00f3s 75 g de glicose \u2265 200 mg\/dL, DMG pr\u00e9vio, obesidade, HbA1c &gt; 6% e hist\u00f3ria familiar de DM em parente de primeiro grau associada \u00e0 obesidade ou DMG pr\u00e9vio, esta \u00faltima a associa\u00e7\u00e3o mais relevante (p &lt; 0,05). CONCLUS\u00d5ES: Os fatores de risco analisados se mostraram altamente sens\u00edveis para a detec\u00e7\u00e3o de DMG, e a disposi\u00e7\u00e3o da hist\u00f3ria familiar refor\u00e7a sua rela\u00e7\u00e3o com o DM2. Recomenda-se maior vigil\u00e2ncia a gestantes com fatores preditivos para necessidade de insulina.<\/jats:p>","DOI":"10.1590\/s0004-27302011000600005","type":"journal-article","created":{"date-parts":[[2011,10,12]],"date-time":"2011-10-12T06:55:10Z","timestamp":1318402510000},"page":"389-398","source":"Crossref","is-referenced-by-count":6,"title":["Marcadores para o diagn\u00f3stico e tratamento de 924 gesta\u00e7\u00f5es com diabetes melito gestacional"],"prefix":"10.1590","volume":"55","author":[{"given":"Josiane Cristine Melchioretto","family":"Detsch","sequence":"first","affiliation":[{"name":"Universidade Federal do Paran\u00e1, Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana Cristina Ravazzani de","family":"Almeida","sequence":"additional","affiliation":[{"name":"Universidade Federal do Paran\u00e1, Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luis Gustavo Cambrussi","family":"Bortolini","sequence":"additional","affiliation":[{"name":"Universidade Federal do Paran\u00e1, Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Denis Jos\u00e9","family":"Nascimento","sequence":"additional","affiliation":[{"name":"Universidade Federal do Paran\u00e1, Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fernando Cesar","family":"Oliveira Junior","sequence":"additional","affiliation":[{"name":"Universidade Federal do Paran\u00e1, Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ros\u00e2ngela Roginski","family":"R\u00e9a","sequence":"additional","affiliation":[{"name":"Universidade Federal do Paran\u00e1, Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"530","reference":[{"issue":"1","key":"ref1","doi-asserted-by":"crossref","first-page":"S43","DOI":"10.2337\/diacare.29.s1.06.s43","article-title":"Diagnosis and classification of diabetes mellitus","volume":"29","author":"American Diabetes Association","year":"2006","journal-title":"Diabetes Care."},{"key":"ref2","doi-asserted-by":"crossref","first-page":"1183","DOI":"10.2337\/diacare.20.7.1183","article-title":"Report of the Expert Committee on the Diagnosis and Classification of Diabetes Mellitus","volume":"20","author":"The Expert Committee on the Diagnosis and Classification of Diabetes Mellitus","year":"1997","journal-title":"Diabetes Care."},{"issue":"1","key":"ref3","first-page":"S88","article-title":"Clinical Practice Recommendations","volume":"27","author":"American Diabetes Association","year":"2004","journal-title":"Gestational diabetes mellitus. Diabetes Care."},{"key":"ref4","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1046\/j.1464-5491.2000.00257.x","article-title":"Prevalence of gestational diabetes mellitus do the WHO criteria make a difference? Brazilian Gestational Diabetes Group","volume":"17","author":"Schmidt MI","year":"2000","journal-title":"Diabet Medic."},{"key":"ref5","first-page":"766","article-title":"Screening for gestational diabetes mellitus: a systematic review for the U","volume":"148","author":"Hillier TA","year":"2008","journal-title":"S. Preventive Services Task Force. Ann Intern Med."},{"key":"ref6","first-page":"848","article-title":"Short stature and gestational diabetes in Brazil","volume":"43","author":"Branchtein L","year":"2000","journal-title":"Brazilian Gestational Diabetes Study Group. Diabetologia."},{"key":"ref7","doi-asserted-by":"crossref","first-page":"997","DOI":"10.1007\/s001250051022","article-title":"Decreased stature in gestational diabetes mellitus","volume":"41","author":"Anastasiou E","year":"1998","journal-title":"Diabetologia."},{"key":"ref8","doi-asserted-by":"crossref","first-page":"1246","DOI":"10.2337\/diacare.21.8.1246","article-title":"for the Brazilian Study of Gestational Diabetes (EBDG) Working Group: fasting plasma glucose is a useful test for the detection of gestational diabetes","volume":"21","author":"Reichelt AJ","year":"1998","journal-title":"Diabetes Care","ISSN":"https:\/\/id.crossref.org\/issn\/0149-5992","issn-type":"print"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"574","DOI":"10.1590\/S0004-27302002000500012","article-title":"Recomenda\u00e7\u00f5es da 2\u00aa reuni\u00e3o de grupo de trabalho em diabetes e gravidez","volume":"46","author":"Reichelt AJ","year":"2002","journal-title":"Arq Bras Endocrinol Metab."},{"issue":"2","key":"ref10","first-page":"S251","article-title":"Summary and Recommendations of the Fifth International Workshop-Conference on Gestational Diabetes Mellitus","volume":"30","author":"American Diabetes Association","year":"2007","journal-title":"Diabetes Care."},{"key":"ref11","series-title":"Definition, diagnosis and classification of diabetes mellitus and its complications: report of a WHO consultation","year":"1999"},{"issue":"7","key":"ref12","doi-asserted-by":"crossref","first-page":"2107","DOI":"10.2337\/diacare.26.7.2107","article-title":"Maternal and fetal outcomes if gestational impaired glucose tolerance is not treated","volume":"26","author":"Hanson U","year":"2003","journal-title":"Diabetes Care."},{"issue":"6","key":"ref13","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1056\/NEJMoa012512","article-title":"Reduction in the Incidence of Type 2 Diabetes with Lifestyle Intervention or Metformin","volume":"346","author":"Diabetes Prevention Program Research Group","year":"2002","journal-title":"N Engl J Med."},{"key":"ref14","doi-asserted-by":"crossref","first-page":"2003","DOI":"10.1056\/NEJMoa0707193","article-title":"Metformin versus insulin for the treatment of gestational diabetes","volume":"358","author":"Rowan JA","year":"2008","journal-title":"N Engl J Med."},{"key":"ref15","first-page":"393","article-title":"Gestational diabetes mellitus - an analysis of risk factors","volume":"59","author":"Cypryk K","year":"2008","journal-title":"Pol J Endocrinol."},{"key":"ref16","doi-asserted-by":"crossref","first-page":"418","DOI":"10.2337\/diacare.22.3.418","article-title":"Effect of selective screening for gestational diabetes","volume":"22","author":"Williams CB","year":"1999","journal-title":"Diabetes Care."},{"key":"ref17","doi-asserted-by":"crossref","first-page":"861","DOI":"10.1002\/(SICI)1096-9136(199610)13:10<861::AID-DIA226>3.0.CO;2-E","article-title":"The diagnosis of \"pathological hyperglycemia\" in gestational diabetes in a high risk obstetric population","volume":"13","author":"Nasrat HA","year":"1996","journal-title":"Diabet Med."},{"key":"ref18","doi-asserted-by":"crossref","first-page":"1003","DOI":"10.1016\/0002-9378(94)90023-X","article-title":"Gestational diabetes: does the presence of risk factors influence perinatal outcomes?","volume":"171","author":"Weeks JW","year":"1994","journal-title":"Am J Obstet Gynecol","ISSN":"https:\/\/id.crossref.org\/issn\/0002-9378","issn-type":"print"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"1078","DOI":"10.1001\/jama.1997.03550130052036","article-title":"A prospective study of pregravid determinations of gestational diabetes mellitus","volume":"278","author":"Solomon CJ","year":"1997","journal-title":"JAMA."},{"key":"ref20","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1186\/1472-6823-9-12","article-title":"history of diabetes and clinical characteristics in Greek subjects with type 2 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Womens Health."},{"issue":"3","key":"ref24","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1097\/AOG.0b013e3181cfce4f","article-title":"Gestational weight gain and risk of gestational diabetes mellitus","volume":"115","author":"Heddderson M","year":"2010","journal-title":"Obstet Gynecol."},{"key":"ref25","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1093\/humupd\/dml036","article-title":"A meta-analysis of pregnancy outcomes in women with polycystic ovary syndrome","volume":"16","author":"Boomsma CM","year":"2006","journal-title":"Hum Reprod Update","ISSN":"https:\/\/id.crossref.org\/issn\/1355-4786","issn-type":"print"},{"key":"ref26","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1016\/j.fertnstert.2008.06.045","article-title":"Risk of gestational diabetes mellitus in women with polycystic ovary syndrome: a systematic review and a meta-analysis","volume":"92","author":"Toulis KA","year":"2009","journal-title":"Fertil Steril."},{"key":"ref27","doi-asserted-by":"crossref","first-page":"1865","DOI":"10.2337\/dc06-2329","article-title":"A1C in gestational diabetes in Asian Indian women","volume":"30","author":"Balaji V","year":"2007","journal-title":"Diabetes Care","ISSN":"https:\/\/id.crossref.org\/issn\/0149-5992","issn-type":"print"},{"key":"ref28","doi-asserted-by":"crossref","first-page":"121","DOI":"10.4103\/0973-3930.45271","article-title":"Glycohemoglobin A1c: a promising screening tool in gestational diabetes mellitus","volume":"28","author":"Aldasouqui SA","year":"2008","journal-title":"Int J Diab Dev Ctries."},{"key":"ref29","series-title":"Definition, diagnosis and classification of diabetes mellitus and its complications: report of a WHO consultation","year":"1999"},{"key":"ref30","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1111\/j.1365-3016.1996.tb00026.x","article-title":"Congenital malformations in newborns of women with established and gestational diabetes in Washington 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