{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,4,5]],"date-time":"2022-04-05T01:10:36Z","timestamp":1649121036887},"reference-count":36,"publisher":"FapUNIFESP (SciELO)","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arq Bras Endocrinol Metab"],"published-print":{"date-parts":[[2012,7]]},"abstract":"<jats:p>OBJECTIVE: The objective of this study was to determine the incidence and etiology of congenital hypothyroidism (CH) in Uberaba, MG. SUBJECTS AND METHODS: From 2001 to 2010, by reviewing patient files from a public reference outpatient unit. The screening program covered 88% of live-born children. RESULTS: CH was diagnosed in 16 children, representing an incidence of 1:2,017 live-born children screened. The etiological evaluation was done in 15 children and revealed seven cases of thyroid dysgenesis, seven of dyshormonogenesis, and one case of transient hypothyroidism. One child moved away from the state before etiological investigation was carried out. CONCLUSION: We concluded that both the incidence of CH and of dyshormonogenesis as the main causes of CH were increased in the investigated region, but molecular studies are necessary for a better definition of etiology.<\/jats:p>","DOI":"10.1590\/s0004-27302012000500005","type":"journal-article","created":{"date-parts":[[2012,8,18]],"date-time":"2012-08-18T07:53:39Z","timestamp":1345276419000},"page":"305-312","source":"Crossref","is-referenced-by-count":4,"title":["Incidence of congenital hypothyroidism in the city of Uberaba\/Minas Gerais and etiological evaluation of the affected subjects"],"prefix":"10.1590","volume":"56","author":[{"given":"Helo\u00edsa Marcelina da Cunha","family":"Palhares","sequence":"first","affiliation":[{"name":"Universidade Federal do Tri\u00e2ngulo Mineiro, Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lilian Carla","family":"Silva","sequence":"additional","affiliation":[{"name":"UFTM, Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luciene Mayumi","family":"Sato","sequence":"additional","affiliation":[{"name":"UFTM, Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Beatriz Hallal Jorge","family":"Lara","sequence":"additional","affiliation":[{"name":"Universidade Federal do Tri\u00e2ngulo Mineiro, Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sybele de Souza Castro","family":"Miranzi","sequence":"additional","affiliation":[{"name":"UFTM, Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adriana de Paula","family":"Silva","sequence":"additional","affiliation":[{"name":"UFTM, Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria de F\u00e1tima","family":"Borges","sequence":"additional","affiliation":[{"name":"Universidade Federal do Tri\u00e2ngulo Mineiro, Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"530","reference":[{"key":"ref1","series-title":"Basic & Clinic Endocrinology","first-page":"209","volume-title":"The thyroid gland","author":"Cooper DS","year":"2007","edition":"8"},{"key":"ref2","series-title":"Endocrinologia para o pediatra","volume-title":"Hipotireoidismo cong\u00eanito","author":"Medeiros-Neto G","year":"2007","edition":"3"},{"issue":"3","key":"ref3","first-page":"95","article-title":"Update on some aspects of neonatal thyroid disease","volume":"2","author":"Rapaport R","year":"2010","journal-title":"J Clin Res Ped Endo"},{"key":"ref4","first-page":"209","article-title":"Hypothyroidism in children: diagnosis and treatment","volume":"83","author":"Setian N","year":"2007","journal-title":"J Pediatr","ISSN":"http:\/\/id.crossref.org\/issn\/0022-3476","issn-type":"print"},{"key":"ref5","first-page":"82","article-title":"A import\u00e2ncia da triagem neonatal no hipotireoidismo cong\u00eanito: an\u00e1lise secund\u00e1ria de dados","volume":"77","author":"Dantas M","year":"2007","journal-title":"Gaz M\u00e9d Bahia"},{"issue":"1","key":"ref6","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1590\/S0004-27302001000100005","article-title":"Gen\u00e9tica molecular do hipotireoidismo cong\u00eanito","volume":"45","author":"Knobel M","year":"2001","journal-title":"Arq Bras Endocrinol Metab"},{"key":"ref7","series-title":"Hipotireoidismo cong\u00eanito. 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