{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T04:29:48Z","timestamp":1783484988573,"version":"3.55.0"},"reference-count":31,"publisher":"FapUNIFESP (SciELO)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arq Bras Endocrinol Metab"],"published-print":{"date-parts":[[2013,6]]},"abstract":"<jats:p>OBJECTIVE: To establish the frequency of U Tg (undetectable pre-ablation thyroglobulin) in TgAb- negative patients and to evaluate the outcome in the follow-up. SUBJECTS AND METHODS: We retrospectively reviewed 335 patients' records. Twenty eight patients (9%) had U Tg. Mean follow-up was 42 \u00b1 38 months. All subjects had undergone total thyroidectomy, and lymph nodes were positive in 13 (46%) patients. Tg and TgAb levels were measured 4 weeks after surgery by IMA technology in hypothyroid state. No evidence of disease (NED) status was defined as undetectable (&lt; 1 ng\/mL) stimulated Tg and negative Tg-Ab and\/or negative WBS, together with normal imaging studies. RESULTS: Seventeen patients (61%) were considered with NED. Four patients (14%) had persistent disease (mediastinum, n = 1, lung n = 2, unknown n = 1), and 7 (25%) had detectable TgAb by other method during their follow-up. CONCLUSIONS: U Tg levels usually is associated to a complete surgery. However, in a low percentage of patients, this may be related to false negative Tg or TgAb measurement.<\/jats:p>","DOI":"10.1590\/s0004-27302013000400004","type":"journal-article","created":{"date-parts":[[2013,7,3]],"date-time":"2013-07-03T23:13:48Z","timestamp":1372893228000},"page":"292-306","source":"Crossref","is-referenced-by-count":2,"title":["Undetectable pre-ablation thyroglobulin levels in patients with differentiated thyroid cancer: it is not always what it seems"],"prefix":"10.1590","volume":"57","author":[{"given":"Fabi\u00e1n","family":"Pitoia","sequence":"first","affiliation":[{"name":"University of Buenos Aires, Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria F.","family":"Bueno","sequence":"additional","affiliation":[{"name":"University of Buenos Aires, Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erika","family":"Abelleira","sequence":"additional","affiliation":[{"name":"University of Buenos Aires, Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria E.","family":"Salvai","sequence":"additional","affiliation":[{"name":"University of Buenos Aires, Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liliana","family":"Bergoglio","sequence":"additional","affiliation":[{"name":"Hospital de Clinicas, Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Markus","family":"Luster","sequence":"additional","affiliation":[{"name":"University of Marburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hugo","family":"Niepomniszcze","sequence":"additional","affiliation":[{"name":"University of Buenos Aires, Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"530","reference":[{"issue":"11","key":"ref1","doi-asserted-by":"crossref","first-page":"1167","DOI":"10.1089\/thy.2009.0110","article-title":"Revised American Thyroid Association management guidelines for patients with 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