{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,2]],"date-time":"2026-04-02T00:51:58Z","timestamp":1775091118964,"version":"3.50.1"},"reference-count":16,"publisher":"FapUNIFESP (SciELO)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arq. Gastroenterol."],"abstract":"<jats:p>ABSTRACT  BACKGROUND:  Norovirus (NoV) is an important etiologic agent of acute gastroenteritis and infects individuals of all ages, especially children in Brazil and worldwide. NoV GII.4 was the most prevalent genotype worldwide because of your extensive genetic diversity. In Brazil, especially in the Northeast, few studies have been developed for identify and molecularly characterize NoV.  OBJECTIVE:  The present study aimed to detect and describe the molecular epidemiology of NoV associated with acute gastroenteritis.  METHODS:  The viral RNA extracted from stool samples were subjected to Nested RT-PCR and the genotypes were determined by nucleotide sequences analysis. In total, 278 stool samples assisted at Alian\u00e7a Hospital in the city of Salvador, with acute gastroenteritis were examined, between March 2009 and July 2012.  RESULTS:  A high NoV rate (54.2%) was identified in children under 5 years of age. We detected the circulation of different NoV GII.4 variants in Salvador, during the study period as Den Haag 2006b, New Orleans 2009 and Sydney 2012.  CONCLUSION:  These findings reinforce the need to study the molecular epidemiology of NoV infections in acute gastroenteritis.<\/jats:p>","DOI":"10.1590\/s0004-2803.201800000-67","type":"journal-article","created":{"date-parts":[[2018,12,15]],"date-time":"2018-12-15T13:30:52Z","timestamp":1544880652000},"page":"264-266","source":"Crossref","is-referenced-by-count":7,"title":["ACUTE GASTROENTERITIS ASSOCIATED WITH NOROVIRUS GII.4 VARIANTS"],"prefix":"10.1590","volume":"55","author":[{"given":"Fabiana Lopes de","family":"PAULA","sequence":"first","affiliation":[{"name":"Universidade Federal da Bahia,  Brazil; Universidade Federal do Rec\u00f4ncavo da Bahia,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Silvia In\u00eas","family":"SARDI","sequence":"additional","affiliation":[{"name":"Universidade Federal da Bahia,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7435-9986","authenticated-orcid":false,"given":"Dellane Martins","family":"TIGRE","sequence":"additional","affiliation":[{"name":"Universidade Federal da Bahia,  Brazil; Universidade Estadual do Sudoeste da Bahia,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Flora Maria de Campos","family":"FERNANDES","sequence":"additional","affiliation":[{"name":"Universidade Federal da Bahia,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G\u00fabio Soares","family":"CAMPOS","sequence":"additional","affiliation":[{"name":"Universidade Federal da Bahia,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"530","published-online":{"date-parts":[[2018,9]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1128\/CMR.00075-14","article-title":"Norovirus","volume":"28","author":"Robilotti 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JJ","year":"2009","journal-title":"JID"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1128\/JCM.01535-14","article-title":"Advances in laboratory methods for detection and typing of Norovirus","volume":"53","author":"Vinj\u00e9 J","year":"2015","journal-title":"J Clin Microbiol"},{"key":"ref16","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0092988","article-title":"Temporal dynamics of Norovirus GII.4 variants in Brazil between 2004-2012","volume":"9","author":"Fioretti JM","year":"2014","journal-title":"PLoS ONE"}],"container-title":["Arquivos de 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