{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,20]],"date-time":"2026-06-20T15:45:57Z","timestamp":1781970357651,"version":"3.54.5"},"reference-count":32,"publisher":"FapUNIFESP (SciELO)","issue":"3","license":[{"start":{"date-parts":[[2022,9,1]],"date-time":"2022-09-01T00:00:00Z","timestamp":1661990400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2022,9,1]],"date-time":"2022-09-01T00:00:00Z","timestamp":1661990400000},"content-version":"am","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2022,9,1]],"date-time":"2022-09-01T00:00:00Z","timestamp":1661990400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arq. Gastroenterol."],"abstract":"<jats:p>ABSTRACT  Background: Gallstones are the presence of bile clay in the gallbladder or bile ducts. The disease can be asymptomatic or symptomatic and can lead to complications and consequently a worse prognosis, such as acute cholecystitis, choledocholithiasis, cholangitis, and acute pancreatitis. The risk of complications increases after the first episode of biliary colic.  Objective: A clinical-epidemiological evaluation of patients admitted to a gastroenterology ward of a tertiary care hospital with gallstone-related complications.  Methods: We evaluated 158 patients admitted through discharge reports and medical records analysis from January 1, 2013, to February 24, 2021.  Results: The female sex was predominant (76.6%), and the mean age of patients was 51.6 years. Men were significantly older than women (P=0.005). Most (57.6%) had some comorbidity, the most frequent being systemic arterial hypertension, diabetes mellitus, and obesity. The mean hospitalization time was 24 days, significantly longer in men (P=0.046) but without a direct relationship with age (P=0.414). The most frequent complication was choledocholithiasis, and 55.7% of patients without previous cholecystectomy had a report of biliary colic before admission, on average 1.5 years previously. A history of a prior cholecystectomy was present in 17.1% of those evaluated. Abdominal ultrasonography followed by magnetic resonance cholangiography was the most frequently performed exam for diagnostic definition. Regarding therapeutic measures, endoscopic retrograde cholangiopancreatography was necessary for 47.3% of patients without previous cholecystectomy and 81.4% of patients who have already had a cholecystectomy. Among patients not yet cholecystectomized, 84% underwent the procedure before discharge.  Conclusion: The female patients were predominant. Men were significantly older than women and had more extended hospital stays. The most frequent complication was choledocholithiasis, and around half of the patients reported previous biliary colic. endoscopic retrograde cholangiopancreatography has been necessary for the majority of the patients.<\/jats:p>","DOI":"10.1590\/s0004-2803.202203000-64","type":"journal-article","created":{"date-parts":[[2022,9,26]],"date-time":"2022-09-26T19:49:26Z","timestamp":1664221766000},"page":"352-357","source":"Crossref","is-referenced-by-count":5,"title":["CLINICAL AND EPIDEMIOLOGICAL EVALUATION OF COMPLICATIONS ASSOCIATED WITH GALLSTONES IN A TERTIARY HOSPITAL"],"prefix":"10.1590","volume":"59","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1493-5299","authenticated-orcid":false,"given":"Ridson Guilherme Parente de","family":"AGUIAR","sequence":"first","affiliation":[{"name":"Centro Universit\u00e1rio Christus (Unichristus),  Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2239-4886","authenticated-orcid":false,"given":"Francisco Emanoel Albuquerque de","family":"SOUZA J\u00daNIOR","sequence":"additional","affiliation":[{"name":"Centro Universit\u00e1rio Christus (Unichristus),  Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3567-0480","authenticated-orcid":false,"given":"Jos\u00e9 Leonardo Gomes","family":"ROCHA J\u00daNIOR","sequence":"additional","affiliation":[{"name":"Centro Universit\u00e1rio Christus (Unichristus),  Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6025-5601","authenticated-orcid":false,"given":"Francisco S\u00e9rgio Rangel de Paula","family":"PESSOA","sequence":"additional","affiliation":[{"name":"Hospital Geral de Fortaleza,  Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8825-945X","authenticated-orcid":false,"given":"Leidiane Pinho da","family":"SILVA","sequence":"additional","affiliation":[{"name":"Centro Universit\u00e1rio Christus (Unichristus),  Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4491-865X","authenticated-orcid":false,"given":"Gard\u00eania Costa do","family":"CARMO","sequence":"additional","affiliation":[{"name":"Centro Universit\u00e1rio Christus (Unichristus),  Brasil; Hospital Geral de Fortaleza,  Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"530","published-online":{"date-parts":[[2022,9]]},"reference":[{"key":"ref1","article-title":"Gallstones: new insights into an old story","volume":"5","author":"Tiderington E","year":"2016","journal-title":"F1000 Faculty 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laparoscopy","volume":"20","author":"Costi R","year":"2014","journal-title":"World J Gastroenterol"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1111\/jmwh.12959","article-title":"Cholelithiasis: Presentation and Management","volume":"64","author":"Littlefield A","year":"2019","journal-title":"J Midwifery Womens Health"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1097\/SGA.0000000000000235","article-title":"Risk Factors for Cholelithiasis","volume":"39","author":"Pak M","year":"2016","journal-title":"Gastroenterol Nurs"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1159\/000064938","article-title":"Cigarette smoking, alcohol use, and gallstone risk in Japanese men","volume":"65","author":"Kono S","year":"2002","journal-title":"Digestion"},{"key":"ref13","first-page":"B5438","article-title":"New determinants for gallstone disease?","volume":"65","author":"Shabanzadeh 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