{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T11:06:28Z","timestamp":1790593588318,"version":"4.1.0"},"reference-count":25,"publisher":"FapUNIFESP (SciELO)","license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"am","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arq. Gastroenterol."],"abstract":"<jats:p>ABSTRACT  Background: Oropharyngeal dysphagia is frequent among individuals with neurological disorders and may impair nutrition and quality of life. Long-term nasoenteric tube use is associated with esophagitis, gastritis, and increased Helicobacter pylori, highlighting the need for safer nutritional alternatives. Percutaneous endoscopic gastrostomy (PEG) is widely used for long-term enteral feeding.  Objective: To evaluate esophageal and gastric inflammatory changes and the presence of H. pylori before and 6 months after PEG placement in patients with neurogenic oropharyngeal dysphagia.  Materials and Methods:  In this prospective study, 42 patients (median age 76 years) underwent upper gastrointestinal endoscopy and rapid urease testing at baseline and six months after PEG placement. Esophagitis and gastritis were classified using the Los Angeles and Sydney systems. McNemar test was applied (P\u22640.05).  Results: Esophagitis decreased from 57% to 5% and gastritis from 52% to 10% (both P&lt;0.001). H. pylori positivity declined from 24% to 12% (P=0.154).  Conclusion: PEG was associated with significant improvement in esophageal and gastric mucosal integrity, supporting its role as a safe long-term nutritional strategy in patients with neurogenic oropharyngeal dysphagia.<\/jats:p>","DOI":"10.1590\/s0004-2803.24612026-034","type":"journal-article","created":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T10:50:58Z","timestamp":1790592658000},"source":"Crossref","is-referenced-by-count":0,"title":["IMPACT OF PERCUTANEOUS ENDOSCOPIC GASTROSTOMY ON THE ESOPHAGEAL\/GASTRIC MUCOSA AND HELICOBACTER PYLORI IN INDIVIDUALS WITH NEUROGENIC OROPHARYNGEAL DYSPHAGIA"],"prefix":"10.1590","volume":"63","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2484-1344","authenticated-orcid":false,"given":"Jo\u00e3o Paulo Galletti","family":"PILON","sequence":"first","affiliation":[{"name":"Universidade Estadual Paulista","place":["Mar\u00edlia, SP, Brasil"]},{"name":"Universidade de Mar\u00edlia","place":["Mar\u00edlia, SP, Brasil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4930-684X","authenticated-orcid":false,"given":"Rodolfo de Oliveira","family":"MEDEIROS","sequence":"additional","affiliation":[{"name":"Universidade de Mar\u00edlia","place":["Mar\u00edlia, SP, Brasil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7010-5874","authenticated-orcid":false,"given":"Paula Cristina","family":"COLA","sequence":"additional","affiliation":[{"name":"Universidade Estadual Paulista","place":["Mar\u00edlia, SP, Brasil"]},{"name":"Universidade de Mar\u00edlia","place":["Mar\u00edlia, SP, Brasil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0983-0444","authenticated-orcid":false,"given":"Suely Mayumi Motonaga","family":"ONOFRI","sequence":"additional","affiliation":[{"name":"Universidade Estadual Paulista","place":["Mar\u00edlia, SP, Brasil"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"530","published-online":{"date-parts":[[2026]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1038\/nrgastro.2015.199","article-title":"Oropharyngeal dysphagia: manifestations and diagnosis","volume":"13","author":"Rommel N","year":"2016","journal-title":"Nat Rev Gastroenterol Hepatol"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"434","DOI":"10.1007\/s00455-016-9695-9","article-title":"A systematic review of the prevalence of oropharyngeal dysphagia in stroke, Parkinson\u2019s disease, Alzheimer\u2019s disease, head injury, and pneumonia","volume":"31","author":"Claire T","year":"2016","journal-title":"Dysphagia"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"594","DOI":"10.1186\/s12913-018-3376-3","article-title":"Impact of oropharyngeal dysphagia on healthcare cost and length of stay in hospital: a systematic review","volume":"18","author":"Stacie A","year":"2018","journal-title":"BMC Health Services Research"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"3400","DOI":"10.1590\/1518-8345.3355.3400","article-title":"Nasogastric\/nasoenteric tube-related adverse events: an integrative review","volume":"29","author":"Motta BL","year":"2021","journal-title":"Rev Latino-Am Enfermagem"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1136\/gutjnl-2023-330616","article-title":"Updates to the modern diagnosis of GERD: Lyon consensus 2.0","volume":"73","author":"Gyawali CP","year":"2024","journal-title":"Gut"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"1730","DOI":"10.14309\/ajg.0000000000002968","article-title":"ACG Clinical Guideline: Treatment of Helicobacter pylori Infection","volume":"119","author":"Chey WD","year":"2024","journal-title":"Am J Gastroenterol"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"250","DOI":"10.4253\/wjge.v14.i5.250","article-title":"Percutaneous endoscopic gastrostomy and jejunostomy: indications and techniques","volume":"14","author":"Fugazza A","year":"2022","journal-title":"World Journal of Gastrointestinal Endoscopy"},{"key":"ref8","doi-asserted-by":"crossref","DOI":"10.1590\/1806-9282.20221733","article-title":"Does enteral nutrition through a percutaneous endoscopic gastrostomy attenuate Helicobacter pylori colonization? 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