{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T22:22:28Z","timestamp":1783030948986,"version":"3.54.6"},"reference-count":16,"publisher":"FapUNIFESP (SciELO)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arq. Gastroenterol."],"published-print":{"date-parts":[[2000,1]]},"abstract":"<jats:p>O objetivo do presente estudo \u00e9 avaliar os efeitos do transplante hep\u00e1tico bem sucedido nas altera\u00e7\u00f5es dos ciclos menstruais e da fertilidade observadas em mulheres com hepatopatia cr\u00f4nica. Doze mulheres com idade de 17 a 54 anos submetidas a transplante hep\u00e1tico foram avaliadas. As seguintes vari\u00e1veis foram analisadas: idade, etiologia da hepatopatia, padr\u00e3o da menstrua\u00e7\u00e3o, per\u00edodo de amenorr\u00e9ia, antes e ap\u00f3s o transplante, e ocorr\u00eancia de gravidez ap\u00f3s o transplante. A idade m\u00e9dia das pacientes foi de 36 \u00b1 12,6 anos. Pacientes com cirrose biliar prim\u00e1ria n\u00e3o apresentavam amenorr\u00e9ia antes do transplante. Os demais pacientes apresentavam amenorr\u00e9ia por 3 meses a 11 anos antes do transplante. Recupera\u00e7\u00e3o r\u00e1pida da menstrua\u00e7\u00e3o ocorreu em todos pacientes ap\u00f3s o transplante (3,1 \u00b1 1,2 meses). Duas pacientes engravidaram um e tr\u00eas anos ap\u00f3s o transplante. Conclui-se deste estudo que a maioria das mulheres que apresenta amenorr\u00e9ia secund\u00e1ria \u00e0 doen\u00e7a hep\u00e1tica avan\u00e7ada, volta a ter ciclos menstruais normais aproximadamente tr\u00eas meses ap\u00f3s o transplante hep\u00e1tico e podem engravidar.<\/jats:p>","DOI":"10.1590\/s0004-28032000000100002","type":"journal-article","created":{"date-parts":[[2005,4,15]],"date-time":"2005-04-15T10:18:33Z","timestamp":1113560313000},"page":"3-6","source":"Crossref","is-referenced-by-count":6,"title":["Normaliza\u00e7\u00e3o dos ciclos menstruais e gravidez ap\u00f3s transplante de f\u00edgado"],"prefix":"10.1590","volume":"37","author":[{"given":"M\u00f4nica Beatriz","family":"PAROLIN","sequence":"first","affiliation":[{"name":"Universidade Federal do Paran\u00e1"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J\u00falio Cezar Uili","family":"COELHO","sequence":"additional","affiliation":[{"name":"Universidade Federal do Paran\u00e1"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elizabeth","family":"BALBI","sequence":"additional","affiliation":[{"name":"Universidade Federal do Paran\u00e1"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J\u00falio Cesar","family":"WIEDERKEHR","sequence":"additional","affiliation":[{"name":"Universidade Federal do Paran\u00e1"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marciano","family":"ANGHINONI","sequence":"additional","affiliation":[{"name":"Universidade Federal do Paran\u00e1"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aissar Eduardo","family":"NASSIF","sequence":"additional","affiliation":[{"name":"Universidade Federal do Paran\u00e1"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"530","reference":[{"key":"ref1","first-page":"84","article-title":"Parenthood after liver transplantation","volume":"1","author":"Armenti VT","year":"1995","journal-title":"Liver Transplant Surg"},{"key":"ref2","first-page":"471","article-title":"Reproductive function after liver transplantation.","volume":"1","author":"Armenti VT","year":"1997","journal-title":"Liver Transpl"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"1191","DOI":"10.1136\/bmj.293.6556.1191","article-title":"Hypogonadism in chronic liver disease: impared release of luteinising hormone","volume":"293","author":"Bannister P","year":"1986","journal-title":"Br Med J","ISSN":"https:\/\/id.crossref.org\/issn\/0007-1447","issn-type":"print"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1016\/0020-7292(93)90556-C","article-title":"Pregnancy after liver transplantation","volume":"41","author":"Baruch Y","year":"1993","journal-title":"Int J Gynaecol Obstet","ISSN":"https:\/\/id.crossref.org\/issn\/0020-7292","issn-type":"print"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1136\/gut.31.3.337","article-title":"Recovery of menstruation and pregnancy after liver transplantation.","volume":"31","author":"Cundy TF","year":"1990","journal-title":"Gut","ISSN":"https:\/\/id.crossref.org\/issn\/0017-5749","issn-type":"print"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1136\/gut.32.2.202","article-title":"Amenorrhoea in women with non alcoholic chronic liver disease","volume":"32","author":"Cundy TF","year":"1991","journal-title":"Gut","ISSN":"https:\/\/id.crossref.org\/issn\/0017-5749","issn-type":"print"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1159\/000200352","article-title":"Normalization of menstrual function after liver transplantation: consequences for contraception","volume":"46","author":"De Koning ND","year":"1990","journal-title":"Digestion","ISSN":"https:\/\/id.crossref.org\/issn\/0012-2823","issn-type":"print"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1055\/s-2007-999362","article-title":"Twin pregnancy after orthotopic liver transplantation, with exacerbation of chronic graft rejection.","volume":"8","author":"Grow DR","year":"1991","journal-title":"Am J Perinatol","ISSN":"https:\/\/id.crossref.org\/issn\/0735-1631","issn-type":"print"},{"key":"ref9","first-page":"140A","article-title":"Pregnancy and liver graft survival","volume":"22","author":"Guy S","year":"1995","journal-title":"Hepatology","ISSN":"https:\/\/id.crossref.org\/issn\/0161-0538","issn-type":"print"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"388","DOI":"10.4065\/70.4.388","article-title":"Reproductive function and outcome of pregnancy after liver transplantation in women","volume":"70","author":"Laifer SA","year":"1995","journal-title":"Mayo Clinic Proc"},{"key":"ref11","first-page":"9","article-title":"Cyclosporine-induced fetotoxicity in the rat","volume":"39","author":"Mason RJ","year":"1985","journal-title":"Transplantation","ISSN":"https:\/\/id.crossref.org\/issn\/0041-1337","issn-type":"print"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/0020-7292(95)02458-O","article-title":"Liver transplantation and pregnancy","volume":"50","author":"Paternoster DM","year":"1995","journal-title":"Int J Gynaecol Obstet","ISSN":"https:\/\/id.crossref.org\/issn\/0020-7292","issn-type":"print"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1097\/00007890-198012000-00001","article-title":"Parenthood following renal and hepatic transplantation","volume":"30","author":"Penn I","year":"1980","journal-title":"Transplantation","ISSN":"https:\/\/id.crossref.org\/issn\/0041-1337","issn-type":"print"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1097\/00007890-199002000-00018","article-title":"Childbearing after liver transplantation","volume":"49","author":"Scantlebury V","year":"1990","journal-title":"Transplantation","ISSN":"https:\/\/id.crossref.org\/issn\/0041-1337","issn-type":"print"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1136\/bmj.293.6542.297","article-title":"Increased incidence of menstrual abnormalities and hysterectomy preceding primary biliary cirrhosis","volume":"293","author":"Stellon AJ","year":"1986","journal-title":"Br Med J","ISSN":"https:\/\/id.crossref.org\/issn\/0007-1447","issn-type":"print"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"896","DOI":"10.1016\/S0002-9378(12)90841-8","article-title":"Pregnancy in liver transplant recipients: course and outcome in 19 cases","volume":"168","author":"Ville Y","year":"1993","journal-title":"Am J Obstet Gynecol","ISSN":"https:\/\/id.crossref.org\/issn\/0002-9378","issn-type":"print"}],"container-title":["Arquivos de Gastroenterologia"],"original-title":[],"link":[{"URL":"http:\/\/www.scielo.br\/pdf\/ag\/v37n1\/6633.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,5,24]],"date-time":"2017-05-24T18:25:38Z","timestamp":1495650338000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.scielo.br\/scielo.php?script=sci_arttext&pid=S0004-28032000000100002&lng=pt&tlng=pt"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2000,1]]},"references-count":16,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2000,1]]}},"alternative-id":["S0004-28032000000100002"],"URL":"https:\/\/doi.org\/10.1590\/s0004-28032000000100002","relation":{},"ISSN":["0004-2803"],"issn-type":[{"value":"0004-2803","type":"electronic"}],"subject":[],"published":{"date-parts":[[2000,1]]}}}