{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T15:19:23Z","timestamp":1753888763838},"reference-count":26,"publisher":"FapUNIFESP (SciELO)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arq. Gastroenterol."],"published-print":{"date-parts":[[2000,1]]},"abstract":"<jats:p>Em pacientes com esofagopatia chag\u00e1sica e pacientes com acal\u00e1sia, a amplitude das contra\u00e7\u00f5es esof\u00e1gicas est\u00e1 diminu\u00edda. Como nem todas as degluti\u00e7\u00f5es s\u00e3o seguidas de contra\u00e7\u00f5es com baixa amplitude, avaliamos o n\u00famero de contra\u00e7\u00f5es com amplitude abaixo de 30 mm Hg em 40 volunt\u00e1rios assintom\u00e1ticos, 99 pacientes com doen\u00e7a de Chagas e 14 pacientes com acal\u00e1sia idiop\u00e1tica. Cada paciente ou volunt\u00e1rio realizou 10 degluti\u00e7\u00f5es de 5 mL de \u00e1gua e o registro das contra\u00e7\u00f5es foi feito a 5 cm, 10 cm e 15 cm proximal ao esf\u00edncter inferior do es\u00f4fago. Neste registro foi utilizado o m\u00e9todo manom\u00e9trico com perfus\u00e3o cont\u00ednua. O n\u00famero de contra\u00e7\u00f5es com hipocontratilidade foi maior nos pacientes com doen\u00e7a de Chagas e pacientes com acal\u00e1sia do que nos volunt\u00e1rios (P &lt;0,05). Pacientes chag\u00e1sicos com tr\u00e2nsito lento no exame radiol\u00f3gico mas sem dilata\u00e7\u00e3o do es\u00f4fago tiveram mais contra\u00e7\u00f5es com baixa amplitude do que pacientes com exame radiol\u00f3gico normal (P &lt;0,01). O mesmo resultado se obteve quando da an\u00e1lise do n\u00famero de indiv\u00edduos com tr\u00eas ou mais contra\u00e7\u00f5es com baixa amplitude (P &lt;0,01). Os pacientes chag\u00e1sicos com disfagia tiveram mais contra\u00e7\u00f5es com hipocontratilidade do que aqueles sem disfagia (P &lt;0,05). Conclu\u00edmos que na doen\u00e7a de Chagas e na acal\u00e1sia idiop\u00e1tica ocorre maior n\u00famero de contra\u00e7\u00f5es esof\u00e1gicas com baixa amplitude do que em pessoas normais, o que deve contribuir para a sintomatologia dos pacientes.<\/jats:p>","DOI":"10.1590\/s0004-28032000000100008","type":"journal-article","created":{"date-parts":[[2005,4,15]],"date-time":"2005-04-15T14:18:33Z","timestamp":1113574713000},"page":"35-41","source":"Crossref","is-referenced-by-count":7,"title":["Hipocontratilidade do es\u00f4fago em pacientes com doen\u00e7a de chagas e pacientes com acal\u00e1sia idiop\u00e1tica"],"prefix":"10.1590","volume":"37","author":[{"given":"Roberto Oliveira","family":"DANTAS","sequence":"first","affiliation":[{"name":"Universidade de S\u00e3o Paulo"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"530","reference":[{"key":"ref1","series-title":"Physiology of the digestive tract","first-page":"903","volume-title":"Motor functions of the pharynx 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