{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,6,4]],"date-time":"2025-06-04T05:44:45Z","timestamp":1749015885356},"reference-count":25,"publisher":"FapUNIFESP (SciELO)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arq. Gastroenterol."],"published-print":{"date-parts":[[2002,3]]},"abstract":"<jats:p>Racional - Metano \u00e9 um g\u00e1s intestinal que pode estar presente no ar expirado de cerca de 10% das crian\u00e7as. Objetivo - Pesquisar a produ\u00e7\u00e3o de metano em crian\u00e7as com constipa\u00e7\u00e3o cr\u00f4nica funcional e a concentra\u00e7\u00e3o de metano no ar expirado antes e depois de evacua\u00e7\u00e3o induzida por enema retal. Material e M\u00e9todos - Foram estudadas 75 crian\u00e7as com idades entre 3 e 13 anos com constipa\u00e7\u00e3o cr\u00f4nica funcional. O metano foi determinado em amostras de ar coletado no final de expira\u00e7\u00e3o volunt\u00e1ria em cromat\u00f3grafo de g\u00e1s Quintron (modelo 12i). Foram consideradas produtoras as crian\u00e7as com metano em concentra\u00e7\u00e3o maior ou igual a 3 partes por milh\u00e3o (ppm). Resultados - Produ\u00e7\u00e3o de metano foi caracterizada em 44 (86,3%) dos 51 pacientes com constipa\u00e7\u00e3o e escape fecal e em apenas 7 (29,2%) dos 24 com constipa\u00e7\u00e3o sem escape fecal. Na 6\u00aa semana de tratamento, constatou-se redu\u00e7\u00e3o de 65,2% no n\u00famero de produtores de metano. A produ\u00e7\u00e3o de metano foi avaliada tamb\u00e9m em 10 crian\u00e7as com h\u00e1bito intestinal normal e nenhuma delas era produtora de metano. No grupo de 20 crian\u00e7as com fecaloma secund\u00e1rio \u00e0 constipa\u00e7\u00e3o cr\u00f4nica, foi avaliada a concentra\u00e7\u00e3o de metano antes e depois da evacua\u00e7\u00e3o induzida por enema de fosfato hipert\u00f4nico. Destes 20 pacientes, 12 eram produtores de metano. A mediana (percentis 25 e 75 entre par\u00eanteses) de metano no ar expirado diminui de 21,5 (15,0-25,5) ppm antes, para 11,0 (4,0 e 12,5) ppm ap\u00f3s a evacua\u00e7\u00e3o. Conclus\u00e3o - A produ\u00e7\u00e3o de metano associa-se com constipa\u00e7\u00e3o com escape fecal e diminui com a redu\u00e7\u00e3o da impac\u00e7\u00e3o fecal.<\/jats:p>","DOI":"10.1590\/s0004-28032002000100012","type":"journal-article","created":{"date-parts":[[2005,4,15]],"date-time":"2005-04-15T14:19:19Z","timestamp":1113574759000},"page":"66-72","source":"Crossref","is-referenced-by-count":6,"title":["Metano no ar expirado de crian\u00e7as com constipa\u00e7\u00e3o cr\u00f4nica funcional"],"prefix":"10.1590","volume":"39","author":[{"given":"Ana Cristina Fontenele","family":"SOARES","sequence":"first","affiliation":[{"name":"Universidade Federal de S\u00e3o Paulo"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Soraia","family":"TAHAN","sequence":"additional","affiliation":[{"name":"Universidade Federal de S\u00e3o 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