{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T05:25:38Z","timestamp":1735709138074,"version":"3.32.0"},"reference-count":57,"publisher":"FapUNIFESP (SciELO)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arq. Gastroenterol."],"published-print":{"date-parts":[[2002,7]]},"abstract":"<jats:p>RACIONAL: A infec\u00e7\u00e3o por Helicobacter pylori \u00e9 reconhecida como a causa mais freq\u00fcente de gastrite cr\u00f4nica em adultos e crian\u00e7as. Seu diagn\u00f3stico \u00e9 realizado com m\u00e9todos invasivos em fragmentos de mucosa g\u00e1strica obtidos com pin\u00e7a endosc\u00f3pica e os n\u00e3o-invasivos. O m\u00e9todo imunoenzim\u00e1tico constitui exame simples, r\u00e1pido e de baixo custo, apresentando alta sensibilidade em pacientes adultos. OBJETIVO: Avaliou-se o m\u00e9todo ELISA prospectivamente em 111 crian\u00e7as e adolescentes. MATERIAL E M\u00c9TODOS: Utilizou-se o kit \"Cobas Core II\" (Roche). Considerou-se Helicobacter pylori positivo quando o teste r\u00e1pido da urease e a histologia resultaram ambos positivos ou quando a cultura foi positiva, e Helicobacter pylori negativo quando todos os testes foram negativos. RESULTADOS: A idade dos 111 pacientes variou de 3 meses a 16 anos, (mediana = 9a 5m; m\u00e9dia = 8a 7m \u00b1 4.0). Infec\u00e7\u00e3o por Helicobacter pylori foi diagnosticada em 47,7% (53\/111). A sensibilidade da sorologia foi de 83,0% e 86,0% e a especificidade foi de 70,6% e 71,0%, utilizando o ponto de corte de 7 U\/mL e 5 U\/mL, respectivamente. Em pacientes maiores de 10 anos de idade, a sensibilidade foi de 90,6% e 96,8% e a especificidade 71,0% e 61,9%, com ponto de corte de 7 U\/mL e 5 U\/mL, respectivamente. Quando foi utilizada somente a cultura positiva como padr\u00e3o ouro e ponto de corte em 5 U\/mL, a sensibilidade foi de 93,3%. CONCLUS\u00c3O: O m\u00e9todo ELISA apresentou boa sensibilidade em crian\u00e7as maiores de 10 anos, utilizando o ponto de corte de 5 U\/mL, por\u00e9m a especificidade foi menor.<\/jats:p>","DOI":"10.1590\/s0004-28032002000300011","type":"journal-article","created":{"date-parts":[[2005,4,15]],"date-time":"2005-04-15T14:19:54Z","timestamp":1113574794000},"page":"198-203","source":"Crossref","is-referenced-by-count":4,"title":["Avalia\u00e7\u00e3o do m\u00e9todo imunoenzim\u00e1tico (ELISA) para diagn\u00f3stico da infec\u00e7\u00e3o por Helicobacter pylori em crian\u00e7as e adolescentes"],"prefix":"10.1590","volume":"39","author":[{"given":"Aurea","family":"Portorreal","sequence":"first","affiliation":[{"name":"Universidade Federal de S\u00e3o Paulo - Escola Paulista de Medicina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elisabete","family":"Kawakami","sequence":"additional","affiliation":[{"name":"Universidade Federal de S\u00e3o Paulo - Escola Paulista de Medicina"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"530","reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"1770","DOI":"10.1128\/JCM.31.7.1770-1773.1993","article-title":"Diagnosis of Helicobacter pylori infection in adults and children using the Malakit Helicobacter pylori, a commercially available enzyme-linked immunosorbent assay","volume":"31","author":"Blecker U","year":"1993","journal-title":"J Clin Microbiol","ISSN":"https:\/\/id.crossref.org\/issn\/0095-1137","issn-type":"print"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"1095","DOI":"10.1016\/0895-4356(94)90095-7","article-title":"The prevalence of Helicobacter pylori positivity in a symptom-free population, aged 1 to 40 years","volume":"47","author":"Blecker U","year":"1994","journal-title":"J Clin Epidemiol","ISSN":"https:\/\/id.crossref.org\/issn\/0895-4356","issn-type":"print"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1097\/00005176-199407000-00014","article-title":"Evolution of Helicobacter pylori positivity in infants born from positive mothers","volume":"19","author":"Blecker U","year":"1994","journal-title":"J Pediatric Gastroenterol Nutr"},{"key":"ref4","article-title":"Sex ratio of Helicobacter pylori infection in childhood","volume":"89","author":"Blecker U","year":"1994","journal-title":"Am J Gastroenterol","ISSN":"https:\/\/id.crossref.org\/issn\/0002-9270","issn-type":"print"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"1549","DOI":"10.1093\/infdis\/168.6.1549","article-title":"Diagnosis of Helicobacter pylori infection in a developing country: comparison of two ELISAs and a seroprevalence study","volume":"68","author":"Bodhidatta L","year":"1993","journal-title":"J Infect Dis","ISSN":"https:\/\/id.crossref.org\/issn\/0022-1899","issn-type":"print"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"1264","DOI":"10.1111\/j.1572-0241.1998.00407.x","article-title":"Validation of a serologic test for the diagnosis of Helicobacter pylori infection and the immune response to urease and CagA in children","volume":"93","author":"Carmorlinga-Ponce M","year":"1998","journal-title":"Am J Gastroenterol","ISSN":"https:\/\/id.crossref.org\/issn\/0002-9270","issn-type":"print"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1097\/00005176-199901000-00009","article-title":"Evaluation of serology, 13C breath test and polymerase chain reaction of stool samples to detect Helicobacter pylori in Bangladeshi children","volume":"28","author":"Casswall TH","year":"1999","journal-title":"J Pediatr Gastroenterol Nutr","ISSN":"https:\/\/id.crossref.org\/issn\/0277-2116","issn-type":"print"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1080\/23771003.1996.12314812","article-title":"Management of Helicobacter pylori infection in ulcer disease","volume":"31","author":"Cave DR","year":"1996","journal-title":"Hospital Practice","ISSN":"https:\/\/id.crossref.org\/issn\/0018-5809","issn-type":"print"},{"key":"ref9","first-page":"208","article-title":"Ensayo inmunoenzim\u00e1tico para el serodiagn\u00f3stico de la infecci\u00f3n de Helicobacter pylori","volume":"49","author":"Chacon EP","year":"1995","journal-title":"Gen","ISSN":"https:\/\/id.crossref.org\/issn\/0016-3503","issn-type":"print"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1542\/peds.96.2.211","article-title":"Helicobacter pylori infection in recurrent abdominal pain childhood: comparison of diagnostic test and therapy","volume":"96","author":"Chong SKF","year":"1995","journal-title":"Pediatrics","ISSN":"https:\/\/id.crossref.org\/issn\/0031-4005","issn-type":"print"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"417","DOI":"10.2307\/3001616","article-title":"Some methods for strengthening the common 2-test","volume":"10","author":"Cochran WC","year":"1954","journal-title":"Biometrics","ISSN":"https:\/\/id.crossref.org\/issn\/0006-341X","issn-type":"print"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"976","DOI":"10.1097\/00006454-199911000-00008","article-title":"Accuracy of serology and 13C-urea breath test for detection of Helicobacter pylori in children","volume":"18","author":"Corvaglia L","year":"1999","journal-title":"Pediatr Infect Dis J","ISSN":"https:\/\/id.crossref.org\/issn\/0891-3668","issn-type":"print"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"768","DOI":"10.1136\/jcp.44.9.768","article-title":"Immune response to Helicobacter pylori in children with recurrent abdominal pain","volume":"44","author":"Crabtree JE","year":"1991","journal-title":"J Clin Pathol","ISSN":"https:\/\/id.crossref.org\/issn\/0021-9746","issn-type":"print"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1097\/00005176-199010000-00005","article-title":"Helicobacter pylori infection and chronic gastritis: clinical, serological and histologic correlations in children treated with amoxicilin and colloidal bismuth subcitrate","volume":"11","author":"De Giacomo C","year":"1990","journal-title":"J Pediatr Gastroenterol Nutr","ISSN":"https:\/\/id.crossref.org\/issn\/0277-2116","issn-type":"print"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1056\/NEJM199002083220603","article-title":"Intrafamilial clustering of Helicobacter pylori infection","volume":"322","author":"Drumm B","year":"1990","journal-title":"N Engl J Med","ISSN":"https:\/\/id.crossref.org\/issn\/0028-4793","issn-type":"print"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1097\/00005176-200002000-00020","article-title":"On behalf of the european paediatric task force on Helicobacter pylori. - Helicobacter pylori infection in children: a consensus statement","volume":"30","author":"Drumm B","year":"2000","journal-title":"J Pediatr Gastroenterol Nutr","ISSN":"https:\/\/id.crossref.org\/issn\/0277-2116","issn-type":"print"},{"key":"ref17","first-page":"3","article-title":"Epidemiology of Helicobacter pylori infection in Barbados","volume":"46","author":"Edwards CN","year":"1997","journal-title":"W I Med J"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"1004","DOI":"10.1016\/0016-5085(89)91616-8","article-title":"A sensitive and specific serological test for detection of Campylobacter pylori","volume":"96","author":"Evans DJ Jr","year":"1989","journal-title":"Gastroenterology","ISSN":"https:\/\/id.crossref.org\/issn\/0016-5085","issn-type":"print"},{"key":"ref19","first-page":"21","article-title":"Accuracy of diagnostic methods used for epidemiological studies of Helicobacter pylori","volume":"9","author":"Feldman RA","year":"1995","journal-title":"Aliment Pharmacol Ther","ISSN":"https:\/\/id.crossref.org\/issn\/0269-2813","issn-type":"print"},{"key":"ref20","first-page":"321","article-title":"Microbiological and serological diagnostic tests for Helicobacter pylori: an overview","volume":"61","author":"Glupczynski Y","year":"1998","journal-title":"Acta Gastroenterol Belg","ISSN":"https:\/\/id.crossref.org\/issn\/0001-5644","issn-type":"print"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1203\/00006450-199705000-00007","article-title":"Helicobacter pylori acquisition in infancy after decline of maternal passive immunity","volume":"41","author":"Gold BD","year":"1997","journal-title":"Pediatr Res","ISSN":"https:\/\/id.crossref.org\/issn\/0031-3998","issn-type":"print"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1128\/JCM.30.1.176-180.1992","article-title":"Evaluation of a commercially available second generation immunoglobulin G enzyme immunoassay for detection of Helicobacter pylori infection","volume":"30","author":"Goossens H","year":"1992","journal-title":"J Clin Microbiol","ISSN":"https:\/\/id.crossref.org\/issn\/0095-1137","issn-type":"print"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1016\/S0022-3476(95)70405-1","article-title":"Association of symptoms with Helicobacter pylori infection in children","volume":"126","author":"Gormally SM","year":"1995","journal-title":"J Pediatr","ISSN":"https:\/\/id.crossref.org\/issn\/0022-3476","issn-type":"print"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"1084","DOI":"10.1007\/BF01297451","article-title":"Seroepidemiology of Helicobacter pylori infection in India: Comparison of developing and develop countries","volume":"36","author":"Graham DY","year":"1991","journal-title":"Dig Dis Sci","ISSN":"https:\/\/id.crossref.org\/issn\/0163-2116","issn-type":"print"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1097\/00007611-199603000-00004","article-title":"Symptoms of gastritis due to Helicobacter pylori in children","volume":"89","author":"Gremse DA","year":"1996","journal-title":"South Med J","ISSN":"https:\/\/id.crossref.org\/issn\/0038-4348","issn-type":"print"},{"key":"ref26","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1097\/00005176-199602000-00004","article-title":"Helicobacter pylori and recurrent abdominal pain in children","volume":"22","author":"Hardikar W","year":"1996","journal-title":"J Pediatr Gastroenterol Nutr","ISSN":"https:\/\/id.crossref.org\/issn\/0277-2116","issn-type":"print"},{"key":"ref27","first-page":"906","article-title":"The role of Helicobacter pylori in children with recurrent abdominal pain","volume":"90","author":"Heldenberg D","year":"1995","journal-title":"Am J Gastroenterol","ISSN":"https:\/\/id.crossref.org\/issn\/0002-9270","issn-type":"print"},{"key":"ref28","doi-asserted-by":"crossref","first-page":"1525","DOI":"10.1128\/JCM.30.6.1525-1528.1992","article-title":"Evaluation of the performance of commercial test kits for detection of Helicobacter pylori antibodies in serum","volume":"30","author":"Hoek FJ","year":"1992","journal-title":"J Clin Microbiol","ISSN":"https:\/\/id.crossref.org\/issn\/0095-1137","issn-type":"print"},{"key":"ref29","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1111\/j.1699-0463.1993.tb00182.x","article-title":"Evaluation of eight commercial kits for Helicobacter pylori IgG antibody detection","volume":"101","author":"Jensen AK","year":"1993","journal-title":"APMIS","ISSN":"https:\/\/id.crossref.org\/issn\/0903-4641","issn-type":"print"},{"key":"ref30","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1128\/CDLI.2.2.149-155.1995","article-title":"Cross-reactive antigens shared by Pseudomonas aeruginosa, Helicobacter pylori, Campylobacter jejuni and Haemophilus influenzae may cause false-positive titers of antibody to H. pylori","volume":"2","author":"Johansen HK","year":"1995","journal-title":"Clin Diagn Lab Immunol","ISSN":"https:\/\/id.crossref.org\/issn\/1071-412X","issn-type":"print"},{"key":"ref31","doi-asserted-by":"crossref","first-page":"1002","DOI":"10.1136\/jcp.37.9.1002","article-title":"Campylobacter-like organisms on the gastric mucosa: culture, histology and serological studies","volume":"37","author":"Jones DM","year":"1984","journal-title":"J Clin Pathol","ISSN":"https:\/\/id.crossref.org\/issn\/0021-9746","issn-type":"print"},{"key":"ref32","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1099\/00222615-22-1-57","article-title":"Antibody to the gastric Campylobacter-like organism (\"Campylobacter pyloridis\") - clinical correlation and distribution in the normal population","volume":"22","author":"Jones DM","year":"1986","journal-title":"J Med Microbiol","ISSN":"https:\/\/id.crossref.org\/issn\/0022-2615","issn-type":"print"},{"key":"ref33","doi-asserted-by":"crossref","first-page":"460","DOI":"10.1086\/515634","article-title":"Use caution with serologic testing for Helicobacter pylori infection in children","volume":"178","author":"Khanna B","year":"1998","journal-title":"J Infect Dis","ISSN":"https:\/\/id.crossref.org\/issn\/0022-1899","issn-type":"print"},{"key":"ref34","first-page":"1138","article-title":"Do commercial serological kits for Helicobacter pylori infection differ in accuracy? A meta-analysis","volume":"91","author":"Loy CT","year":"1996","journal-title":"Am J Gastroenterol","ISSN":"https:\/\/id.crossref.org\/issn\/0002-9270","issn-type":"print"},{"key":"ref35","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1016\/0929-693X(96)84686-0","article-title":"L`infection symptomatique \u00e0 Helicobacter pylori: \u00e8tude prospective des aspects \u00e8pid\u00e9miologiques, diagnostiques et th\u00e9rapeutiques chez l`enfant en Tunisie","volume":"3","author":"Maherzi A","year":"1996","journal-title":"Arch P\u00e9diatr"},{"key":"ref36","doi-asserted-by":"crossref","first-page":"813","DOI":"10.1016\/0016-5085(92)90011-M","article-title":"Helicobacter pylori in hispanics: comparison with blacks and whites of similar age and socioeconomic class","volume":"103","author":"Malaty HM","year":"1992","journal-title":"Gastroenterology","ISSN":"https:\/\/id.crossref.org\/issn\/0016-5085","issn-type":"print"},{"key":"ref37","doi-asserted-by":"crossref","first-page":"742","DOI":"10.1136\/gut.35.6.742","article-title":"Importance of childhood socioeconomic status on the current prevalence of Helicobacter pylori infection","volume":"35","author":"Malaty HM","year":"1994","journal-title":"Gut","ISSN":"https:\/\/id.crossref.org\/issn\/0017-5749","issn-type":"print"},{"key":"ref38","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/S0140-6736(84)90318-0","article-title":"Pyloric campilobacter serology","volume":"2","author":"Marshall BJ","year":"1984","journal-title":"Lancet","ISSN":"https:\/\/id.crossref.org\/issn\/0099-5355","issn-type":"print"},{"key":"ref39","doi-asserted-by":"crossref","first-page":"57","DOI":"10.3109\/00365529609094536","article-title":"Advantages and disadvantages of current diagnostic test for the detection of Helicobacter pylori","volume":"31","author":"M\u00e9graud F","year":"1996","journal-title":"Scand J Gastroenterol","ISSN":"https:\/\/id.crossref.org\/issn\/0036-5521","issn-type":"print"},{"key":"ref40","first-page":"163","article-title":"Identification of the outer membrane proteins of C. pyloridis and C. jejuni","volume":"133","author":"Newell DG.","year":"1987","journal-title":"J Gen Microbiol","ISSN":"https:\/\/id.crossref.org\/issn\/0022-1287","issn-type":"print"},{"key":"ref41","doi-asserted-by":"crossref","first-page":"572","DOI":"10.1007\/BF01297021","article-title":"Helicobacter pylori in children with peptic ulcer and their families","volume":"36","author":"Oderda G","year":"1991","journal-title":"Dig Dis Sci","ISSN":"https:\/\/id.crossref.org\/issn\/0163-2116","issn-type":"print"},{"key":"ref42","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1590\/S1516-31802001000200006","article-title":"Evaluation of invasive and non-invasive methods for the diagnosis of Helicobacter pylori infection in symptomatic children and adolescents","volume":"119","author":"Ogata SK","year":"2000","journal-title":"S\u00e3o Paulo Med J"},{"key":"ref43","first-page":"2201","article-title":"Seroprevalence of Helicobacter pylori infection in children of low socioeconomic level in Belo Horizonte, Brazil","volume":"89","author":"Oliveira AMR","year":"1994","journal-title":"Am J Gastroenterol","ISSN":"https:\/\/id.crossref.org\/issn\/0002-9270","issn-type":"print"},{"key":"ref44","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1097\/00005176-199902000-00012","article-title":"Evaluation of enzyme-linked immunosorbent assay for the diagnosis of Helicobacter pylori infection in children from different age groups with and without duodenal ulcer","volume":"28","author":"Oliveira AMR","year":"1999","journal-title":"J Pediatr Gastroenterol Nutr","ISSN":"https:\/\/id.crossref.org\/issn\/0277-2116","issn-type":"print"},{"key":"ref45","doi-asserted-by":"crossref","first-page":"1238","DOI":"10.1136\/bmj.303.6812.1238","article-title":"Eradicating Helicobacter pylori and symptoms of non-ulcer dyspepsia","volume":"303","author":"Patchett S","year":"1991","journal-title":"Br Med J","ISSN":"https:\/\/id.crossref.org\/issn\/0007-1447","issn-type":"print"},{"key":"ref46","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1128\/IAI.51.1.204-208.1986","article-title":"Lipopolysaccharide structures in enterobacteriaceae, Pseudomonas aeruginosa and Vibrio cholerae are immunologically related to Campylobacter spp","volume":"51","author":"Perez-Perez GI","year":"1986","journal-title":"Infect Immun","ISSN":"https:\/\/id.crossref.org\/issn\/0019-9567","issn-type":"print"},{"key":"ref47","first-page":"954","article-title":"Helicobacter pylori serology in patients with chronic gastritis","volume":"91","author":"Plebani M","year":"1996","journal-title":"Am J Gastroenterol","ISSN":"https:\/\/id.crossref.org\/issn\/0002-9270","issn-type":"print"},{"key":"ref48","doi-asserted-by":"crossref","first-page":"642","DOI":"10.1136\/gut.27.6.642","article-title":"Systemic and local antibody responses to gastric Campylobacter pyloridis in non-ulcer dyspepsia","volume":"27","author":"Rathbone BJ","year":"1986","journal-title":"Gut","ISSN":"https:\/\/id.crossref.org\/issn\/0017-5749","issn-type":"print"},{"key":"ref49","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1097\/00005176-199304000-00004","article-title":"Serodiagnosis of Helicobacter pylori infection in children by an indirect immunofluorescense test","volume":"16","author":"Rocha GA","year":"1993","journal-title":"J Pediatr Gastroenterol Nutr","ISSN":"https:\/\/id.crossref.org\/issn\/0277-2116","issn-type":"print"},{"key":"ref50","article-title":"Serodiagnosis of Helicobacter pylori (Hp) infection by a second generation ELISA test: comparison between adults and children","volume":"39","author":"Rocha GA","year":"1996","journal-title":"Gut","ISSN":"https:\/\/id.crossref.org\/issn\/0017-5749","issn-type":"print"},{"key":"ref51","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1097\/00005176-199903000-00015","article-title":"Helicobacter pylori and nonulcer dyspepsia in childhood: clinical pattern, diagnostic techniques and bacterial strains","volume":"28","author":"Rutigliano V","year":"1999","journal-title":"J Pediatr Gastroenterol Nutr","ISSN":"https:\/\/id.crossref.org\/issn\/0277-2116","issn-type":"print"},{"key":"ref52","doi-asserted-by":"crossref","first-page":"251","DOI":"10.4067\/S0370-41061997000600001","article-title":"Infecci\u00f3n por Helicobacter pylori y da\u00f1o g\u00e1strico en ni\u00f1os de nivel socioecon\u00f3mico bajo","volume":"68","author":"Sarmiento QF","year":"1997","journal-title":"Rev Chil Pediatr","ISSN":"https:\/\/id.crossref.org\/issn\/0370-4106","issn-type":"print"},{"key":"ref53","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1016\/0140-6736(91)90085-4","article-title":"Screening dyspepsia by serology to Helicobacter pylori","volume":"338","author":"Sobola GM","year":"1991","journal-title":"Lancet","ISSN":"https:\/\/id.crossref.org\/issn\/0099-5355","issn-type":"print"},{"key":"ref54","doi-asserted-by":"crossref","first-page":"1120","DOI":"10.1093\/infdis\/174.5.1120","article-title":"A population-based serologic survey of Helicobacter pylori infection in children and adolescents in the United States","volume":"174","author":"Staat MA","year":"1996","journal-title":"J Infect Dis","ISSN":"https:\/\/id.crossref.org\/issn\/0022-1899","issn-type":"print"},{"key":"ref55","first-page":"2125","article-title":"Diagnostic tests for Helicobacter pylori: a prospective evaluation of their accuracy, without selecting a single test as the gold standard","volume":"91","author":"Thijs JC","year":"1996","journal-title":"Am J Gastroenterol","ISSN":"https:\/\/id.crossref.org\/issn\/0002-9270","issn-type":"print"},{"key":"ref56","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1128\/JCM.29.2.283-286.1991","article-title":"Usefulness of a new serological test (Bio-Rad) to diagnose Helicobacter pylori-associated gastritis","volume":"29","author":"Van Den Oever HLA","year":"1991","journal-title":"J Clin Microbiol","ISSN":"https:\/\/id.crossref.org\/issn\/0095-1137","issn-type":"print"},{"key":"ref57","doi-asserted-by":"crossref","first-page":"608","DOI":"10.1542\/peds.90.4.608","article-title":"Contribution of the 13C-urea breath test to the detection of Helicobacter pylori gastritis in children","volume":"90","author":"Vandenplas Y","year":"1992","journal-title":"Pediatrics","ISSN":"https:\/\/id.crossref.org\/issn\/0031-4005","issn-type":"print"}],"container-title":["Arquivos de Gastroenterologia"],"original-title":[],"link":[{"URL":"http:\/\/www.scielo.br\/pdf\/ag\/v39n3\/15648.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,12,31]],"date-time":"2024-12-31T18:28:30Z","timestamp":1735669710000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.scielo.br\/scielo.php?script=sci_arttext&pid=S0004-28032002000300011&lng=pt&tlng=pt"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2002,7]]},"references-count":57,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2002,7]]}},"alternative-id":["S0004-28032002000300011"],"URL":"https:\/\/doi.org\/10.1590\/s0004-28032002000300011","relation":{},"ISSN":["0004-2803"],"issn-type":[{"type":"electronic","value":"0004-2803"}],"subject":[],"published":{"date-parts":[[2002,7]]}}}