{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,3,31]],"date-time":"2022-03-31T05:21:28Z","timestamp":1648704088954},"reference-count":30,"publisher":"FapUNIFESP (SciELO)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arq. Gastroenterol."],"published-print":{"date-parts":[[2006,12]]},"abstract":"<jats:p>RACIONAL: O trato gastrointestinal \u00e9 freq\u00fcentemente acometido nas crian\u00e7as infectadas pelo v\u00edrus da imunodefici\u00eancia humana, com importantes repercuss\u00f5es no seu estado nutricional e sobrevida. A maioria dos estudos relacionados a esse tema foi desenvolvida com adultos, sendo menos investigado o problema nas crian\u00e7as OBJETIVOS: Estudar aspectos digestivo-absortivos, microbiol\u00f3gicos e morfol\u00f3gicos intestinais em crian\u00e7as infectadas pelo v\u00edrus da imunodefici\u00eancia humana MATERIAL E M\u00c9TODOS: Onze crian\u00e7as infectadas pelo v\u00edrus da imunodefici\u00eancia humana, menores de 13 anos, pertencentes \u00e0s categorias cl\u00ednicas A, B ou C, divididas em dois grupos: cinco pacientes com relato atual ou recente de diarr\u00e9ia e seis pacientes sem diarr\u00e9ia nos 30 dias que antecederam \u00e0 inclus\u00e3o no estudo. Investiga\u00e7\u00e3o proposta: biopsia de intestino delgado e reto para an\u00e1lise morfol\u00f3gica e microbiol\u00f3gica, coprocultura, protoparasitol\u00f3gico de fezes, pesquisa de rotav\u00edrus, micobact\u00e9rias e Cryptosporidium; teste da D-xilose RESULTADOS: Todos os pacientes testados (9\/11) apresentavam m\u00e1 absor\u00e7\u00e3o da D-xilose (8,4-24,4 mg\/dL). Os achados histopatol\u00f3gicos de intestino delgado foram inespec\u00edficos, representados em sua maioria, por enteropatia grau I a II (6\/10). Em todos os casos foi constatado aumento do infiltrado celular do c\u00f3rion. As altera\u00e7\u00f5es histopatol\u00f3gicas do reto tamb\u00e9m foram inespec\u00edficas, com presen\u00e7a de aumento do infiltrado celular do c\u00f3rion. A pesquisa de microorganismos enteropatog\u00eanicos s\u00f3 foi positiva em dois casos, sendo identificado Mycobacterium avium intracellulare e Cryptosporidium nas fezes CONCLUS\u00d5ES: Demonstrou-se alta preval\u00eancia (100%) de m\u00e1 absor\u00e7\u00e3o intestinal em crian\u00e7as infectadas pelo v\u00edrus da imunodefici\u00eancia humana, com ou sem diarr\u00e9ia. N\u00e3o foi poss\u00edvel estabelecer correla\u00e7\u00f5es quanto \u00e0 presen\u00e7a de agentes enteropatog\u00eanicos, m\u00e1 absor\u00e7\u00e3o intestinal, altera\u00e7\u00f5es morfol\u00f3gicas intestinais e ocorr\u00eancia ou n\u00e3o de diarr\u00e9ia. N\u00e3o houve correla\u00e7\u00e3o entre os valores de D-xilose e os graus de atrofia vilosit\u00e1ria.<\/jats:p>","DOI":"10.1590\/s0004-28032006000400013","type":"journal-article","created":{"date-parts":[[2007,4,11]],"date-time":"2007-04-11T13:29:42Z","timestamp":1176298182000},"page":"310-315","source":"Crossref","is-referenced-by-count":3,"title":["Aspectos funcionais, microbiol\u00f3gicos e morfol\u00f3gicos intestinais em crian\u00e7as infectadas pelo v\u00edrus da imunodefici\u00eancia humana"],"prefix":"10.1590","volume":"43","author":[{"given":"Christiane Araujo Chaves","family":"Leite","sequence":"first","affiliation":[{"name":"Universidade Federal do Cear\u00e1"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Regina C\u00e9lia de Menezes","family":"Succi","sequence":"additional","affiliation":[{"name":"Universidade Federal de S\u00e3o Paulo"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francy Reis da Silva","family":"Patr\u00edcio","sequence":"additional","affiliation":[{"name":"Universidade Federal de S\u00e3o Paulo"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ulysses","family":"Fagundes-Neto","sequence":"additional","affiliation":[{"name":"Universidade Federal de S\u00e3o Paulo"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"530","reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"s37","DOI":"10.1097\/00126334-200010001-00006","article-title":"Growth failure in children with HIV infection","volume":"25","author":"Arpadi SM","year":"2000","journal-title":"J Aquir Immune Defic Syndr."},{"key":"ref2","first-page":"45","article-title":"Nomenclatura e classifica\u00e7\u00e3o de desnutri\u00e7\u00e3o: 1. 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