{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,5,29]],"date-time":"2022-05-29T11:05:50Z","timestamp":1653822350563},"reference-count":37,"publisher":"FapUNIFESP (SciELO)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arq. Gastroenterol."],"published-print":{"date-parts":[[2007,6]]},"abstract":"<jats:p>RACIONAL: O megaes\u00f4fago constitui problema de sa\u00fade p\u00fablica em nosso pa\u00eds, pois acomete indiv\u00edduos em sua fase de maior produtividade. Os doentes com essa afec\u00e7\u00e3o podem apresentar em sua evolu\u00e7\u00e3o associa\u00e7\u00e3o com c\u00e2ncer do es\u00f4fago. OBJETIVO: Analisar os aspectos cl\u00ednicos e epidemiol\u00f3gicos de pacientes com megaes\u00f4fago e c\u00e2ncer do es\u00f4fago. M\u00c9TODOS: Foram avaliados de maneira retrospectiva 20 pacientes com megaes\u00f4fago e c\u00e2ncer (grupo 1) e 20 com c\u00e2ncer do es\u00f4fago (grupo 2). Estudaram-se os dados demogr\u00e1ficos, h\u00e1bitos (etilismo e tabagismo), tipo histol\u00f3gico do tumor, localiza\u00e7\u00e3o da les\u00e3o, diferencia\u00e7\u00e3o celular, est\u00e1dio, tratamento e sobrevida. RESULTADOS: N\u00e3o foi observada diferen\u00e7a entre os grupos, com rela\u00e7\u00e3o \u00e0 idade, sexo, localiza\u00e7\u00e3o da les\u00e3o, tipo histol\u00f3gico do tumor, diferencia\u00e7\u00e3o celular, est\u00e1dio e sobrevida. Com rela\u00e7\u00e3o aos h\u00e1bitos de vida, a associa\u00e7\u00e3o de etilismo e tabagismo foi observada em maior n\u00famero de pacientes com c\u00e2ncer do es\u00f4fago sem o antecedente de megaes\u00f4fago. CONCLUS\u00c3O: As caracter\u00edsticas cl\u00ednicas dos pacientes com megaes\u00f4fago e c\u00e2ncer n\u00e3o diferem daqueles com neoplasia maligna esof\u00e1gica n\u00e3o associada ao megaes\u00f4fago, principalmente no que se refere ao progn\u00f3stico desfavor\u00e1vel frente ao tratamento institu\u00eddo. Nos pacientes com megaes\u00f4fago o tumor pode se localizar em qualquer por\u00e7\u00e3o do \u00f3rg\u00e3o.<\/jats:p>","DOI":"10.1590\/s0004-28032007000200013","type":"journal-article","created":{"date-parts":[[2007,11,17]],"date-time":"2007-11-17T12:48:39Z","timestamp":1195303719000},"page":"151-155","source":"Crossref","is-referenced-by-count":10,"title":["C\u00e2ncer do es\u00f4fago em paciente com megaes\u00f4fago chag\u00e1sico"],"prefix":"10.1590","volume":"44","author":[{"given":"Maria Aparecida Coelho de Arruda","family":"Henry","sequence":"first","affiliation":[{"name":"Universidade Estadual Paulista"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mauro Masson","family":"Lerco","sequence":"additional","affiliation":[{"name":"Universidade Estadual Paulista"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Walmar Kerche de","family":"Oliveira","sequence":"additional","affiliation":[{"name":"Universidade Estadual Paulista"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"530","reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1590\/S0004-28032000000100006","article-title":"Mate (chimarr\u00e3o) \u00e9 consumido em alta temperatura por popula\u00e7\u00e3o sob risco para o carcinoma epiderm\u00f3ide do es\u00f4fago","volume":"37","author":"Barros SG","year":"2000","journal-title":"Arq Gastroenterol","ISSN":"http:\/\/id.crossref.org\/issn\/0004-2803","issn-type":"print"},{"key":"ref2","first-page":"169","article-title":"Carcinoma do es\u00f4fago em megaes\u00f4fago chag\u00e1sico ap\u00f3s opera\u00e7\u00e3o de Merendino","volume":"83","author":"Brandalise NA","year":"1974","journal-title":"Rev Paul Med","ISSN":"http:\/\/id.crossref.org\/issn\/0035-0362","issn-type":"print"},{"key":"ref3","first-page":"196","article-title":"Carcinoma associado a megaes\u00f4fago chag\u00e1sico","volume":"12","author":"Brandalise NA","year":"1985","journal-title":"Rev Col Bras Cir","ISSN":"http:\/\/id.crossref.org\/issn\/0100-6991","issn-type":"print"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1007\/s00268-001-0026-3","article-title":"Achalasia and esophageal cancer: incidence, prevalence and prognosis","volume":"25","author":"Br\u00fccher BL","year":"2001","journal-title":"World J Surg","ISSN":"http:\/\/id.crossref.org\/issn\/0364-2313","issn-type":"print"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"742","DOI":"10.1007\/BF02231058","article-title":"Carcinoma of the esophagus as a complication of megaesophagus: An analysis of seven cases","volume":"6","author":"Camara-Lopes LH.","year":"1961","journal-title":"Am J Dig Dis","ISSN":"http:\/\/id.crossref.org\/issn\/0002-9211","issn-type":"print"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"1105","DOI":"10.1007\/BF01317084","article-title":"Achalasia as a risk factor for esophageal carcinoma: A reappraisal","volume":"29","author":"Chuong JJ","year":"1984","journal-title":"Dig Dis Sci","ISSN":"http:\/\/id.crossref.org\/issn\/0163-2116","issn-type":"print"},{"key":"ref7","author":"Crema E","year":"2005"},{"key":"ref8","volume":"32","year":"2005","journal-title":"Rev Col Bras Cir","ISSN":"http:\/\/id.crossref.org\/issn\/0100-6991","issn-type":"print"},{"key":"ref9","author":"Crema E","year":"2005"},{"key":"ref10","volume":"32","year":"2005","journal-title":"Rev Col Bras Cir","ISSN":"http:\/\/id.crossref.org\/issn\/0100-6991","issn-type":"print"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1002\/bjs.1800670702","article-title":"Oesophageal squamous cell carcinomas: A critical review of radiotherapy","volume":"67","author":"Earlam R","year":"1980","journal-title":"Br J Surg","ISSN":"http:\/\/id.crossref.org\/issn\/0007-1323","issn-type":"print"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1093\/dote\/10.1.55","article-title":"Esophageal achalasia and adenocarcinoma in Barrett\u2019s esophagus: a report of two cases and a review of the literature","volume":"10","author":"Ellis FH Jr","year":"1997","journal-title":"Dis Esophagus","ISSN":"http:\/\/id.crossref.org\/issn\/1120-8694","issn-type":"print"},{"key":"ref13","first-page":"6502","article-title":"Smoking and drinking in relation to cancers of the oral cavity, pharynx, larynx and esophagus in northern Italy","volume":"50","author":"Franceschi S","year":"1990","journal-title":"Cancer Res","ISSN":"http:\/\/id.crossref.org\/issn\/0008-5472","issn-type":"print"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"1549","DOI":"10.1007\/BF01540574","article-title":"Esophageal adenocarcinoma in a patient with surgically treated achalasia","volume":"35","author":"Goodman P","year":"1990","journal-title":"Dig Dis Sci","ISSN":"http:\/\/id.crossref.org\/issn\/0163-2116","issn-type":"print"},{"key":"ref15","series-title":"Oncologia b\u00e1sica para profissionais de sa\u00fade","first-page":"21","author":"Haagedoorn EM","year":"2000"},{"key":"ref16","first-page":"8","article-title":"The importance of esophageal manometry in diagnosis and management of megaesophagus","volume":"6","author":"Henry MACA","year":"1991","journal-title":"ABCD Arq Bras Cir Dig"},{"key":"ref17","series-title":"Gastroenterologia essencial","first-page":"96","volume-title":"Megaes\u00f4fago e acal\u00e1sia","author":"Henry MACA","year":"1998"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"536","DOI":"10.1111\/j.1572-0241.1998.161_b.x","article-title":"The development of dysplasia and adenocarcinoma during endoscopic surveillance of Barrett\u2019s esophagus","volume":"93","author":"Katz D","year":"1998","journal-title":"Am J Gastroenterol","ISSN":"http:\/\/id.crossref.org\/issn\/0002-9270","issn-type":"print"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1136\/thx.40.10.795","article-title":"Squamous carcinoma in situ of the oesophagus in a patient with achalasia","volume":"40","author":"Lamb RK","year":"1985","journal-title":"Thorax","ISSN":"http:\/\/id.crossref.org\/issn\/0040-6376","issn-type":"print"},{"key":"ref20","first-page":"1517","article-title":"Mutagenic and genotoxic effects of mate (Ilex paraguariensis) in prokaryotic organisms","volume":"27","author":"Leit\u00e3o AC","year":"1994","journal-title":"Brazilian J Med Biol Res"},{"key":"ref21","series-title":"Using and understanding medical statistics","author":"Mathews DE","year":"1996","edition":"3"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1136\/gut.33.2.155","article-title":"Achalasia complicated by oesophageal squamous cell carcinoma: a prospective study in 195 patients","volume":"33","author":"Meijssen MA","year":"1992","journal-title":"Gut","ISSN":"http:\/\/id.crossref.org\/issn\/0017-5749","issn-type":"print"},{"key":"ref23","first-page":"379","article-title":"O problema do c\u00e2ncer no megaes\u00f4fago","volume":"26","author":"Pinotti HW","year":"1980","journal-title":"Rev Assoc Med Bras","ISSN":"http:\/\/id.crossref.org\/issn\/0004-5241","issn-type":"print"},{"key":"ref24","first-page":"277","article-title":"Carcinoma do es\u00f4fago e estenose c\u00e1ustica: Considera\u00e7\u00f5es sobre 3 casos","volume":"72","author":"Pinotti HW","year":"1982","journal-title":"Rev Bras Cir","ISSN":"http:\/\/id.crossref.org\/issn\/0034-7124","issn-type":"print"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1097\/00001648-199411000-00005","article-title":"Mat\u00e9, coffee, and tea comsuption and risk of cancers of the upper aerodigestive tract in southern Brazil","volume":"5","author":"Pintos J","year":"1994","journal-title":"Epidemiology","ISSN":"http:\/\/id.crossref.org\/issn\/1044-3983","issn-type":"print"},{"key":"ref26","author":"Pombo L","year":"2005"},{"key":"ref27","first-page":"517","volume":"32","year":"2005","journal-title":"Rev Col Bras Cir","ISSN":"http:\/\/id.crossref.org\/issn\/0100-6991","issn-type":"print"},{"key":"ref28","first-page":"217","article-title":"Diferen\u00e7as geogr\u00e1ficas na mortalidade por c\u00e2ncer de es\u00f4fago no Rio Grande do Sul","volume":"39","author":"Prolla JC","year":"1993","journal-title":"Rev Assoc Med Bras","ISSN":"http:\/\/id.crossref.org\/issn\/0004-5241","issn-type":"print"},{"key":"ref29","first-page":"247","article-title":"Aspectos cl\u00ednicos e radiol\u00f3gicos da aperistalse do es\u00f4fago","volume":"12","author":"Rezende JM","year":"1960","journal-title":"Rev Bras Gastroenterol","ISSN":"http:\/\/id.crossref.org\/issn\/0034-7221","issn-type":"print"},{"key":"ref30","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1002\/bjs.1800840244","article-title":"Risk factors for squamous cell carcinoma of the oesophagus","volume":"84","author":"Ribeiro U Jr","year":"1997","journal-title":"Br J Surg","ISSN":"http:\/\/id.crossref.org\/issn\/0007-1323","issn-type":"print"},{"key":"ref31","first-page":"19","article-title":"Hiperexpress\u00e3o e muta\u00e7\u00e3o do gene p 53 em bi\u00f3psias endosc\u00f3picas de pacientes com megaes\u00f4fago chag\u00e1sico","volume":"19","author":"Safatle-Ribeiro AV","year":"2000","journal-title":"GED Gastroenterol Endosc Dig"},{"key":"ref32","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1097\/00000658-200012000-00002","article-title":"Limited resection for early adenocarcinoma in Barrett\u2019s esophagus","volume":"232","author":"Stein H","year":"2000","journal-title":"Ann Surg","ISSN":"http:\/\/id.crossref.org\/issn\/0003-4932","issn-type":"print"},{"key":"ref33","doi-asserted-by":"crossref","first-page":"1604","DOI":"10.1016\/0003-4975(94)00997-L","article-title":"Achalasia and squamous cell carcinoma of the esophagus: analysis of 241 patients","volume":"59","author":"Streitz JM","year":"1995","journal-title":"Ann Thorac Surg","ISSN":"http:\/\/id.crossref.org\/issn\/0003-4975","issn-type":"print"},{"key":"ref34","first-page":"91","article-title":"Incid\u00eancia de carcinoma na esofagite c\u00e1ustica","volume":"6","author":"Sugai BM","year":"1987","journal-title":"GED Gastronterol Endosc Dig"},{"key":"ref35","first-page":"7112","article-title":"Patterns of mat\u00e9 drinking in a Brazilian City","volume":"50","author":"Victora CG","year":"1990","journal-title":"Cancer Res","ISSN":"http:\/\/id.crossref.org\/issn\/0008-5472","issn-type":"print"},{"key":"ref36","first-page":"1687","article-title":"Lugol dye endoscopy for analysis of esophageal mucosa in achalasia","volume":"46","author":"Yamamuro EM","year":"1999","journal-title":"Hepatogastroenterology","ISSN":"http:\/\/id.crossref.org\/issn\/0172-6390","issn-type":"print"},{"key":"ref37","series-title":"Esofagectomia c\u00e9rvico abdominal por via transdiafragm\u00e1tica no tratamento cir\u00fargico do c\u00e2ncer do es\u00f4fago: resultados e evolu\u00e7\u00e3o a longo prazo","author":"Zilberstein B","year":"1988"}],"container-title":["Arquivos de Gastroenterologia"],"original-title":[],"link":[{"URL":"http:\/\/www.scielo.br\/pdf\/ag\/v44n2\/a13v44n2.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,4]],"date-time":"2019-05-04T13:22:06Z","timestamp":1556976126000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.scielo.br\/scielo.php?script=sci_arttext&pid=S0004-28032007000200013&lng=pt&tlng=pt"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,6]]},"references-count":37,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2007,6]]}},"alternative-id":["S0004-28032007000200013"],"URL":"https:\/\/doi.org\/10.1590\/s0004-28032007000200013","relation":{},"ISSN":["0004-2803"],"issn-type":[{"value":"0004-2803","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,6]]}}}