{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,4,4]],"date-time":"2022-04-04T05:46:12Z","timestamp":1649051172032},"reference-count":49,"publisher":"FapUNIFESP (SciELO)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arq. Gastroenterol."],"published-print":{"date-parts":[[2007,9]]},"abstract":"<jats:p>RACIONAL: A doen\u00e7a cel\u00edaca \u00e9 afec\u00e7\u00e3o inflamat\u00f3ria do intestino delgado associada \u00e0 intoler\u00e2ncia permanente ao gl\u00faten, que ocorre em indiv\u00edduos geneticamente suscept\u00edveis. OBJETIVO: Conhecer as caracter\u00edsticas cl\u00ednicas e epidemiol\u00f3gicas dessa doen\u00e7a em nosso meio. M\u00c9TODO: Tratou-se de estudo descritivo transversal com amostra n\u00e3o-probabil\u00edstica selecionada entre os membros da Associa\u00e7\u00e3o dos Cel\u00edacos do Brasil - Regional de Santa Catarina, aos quais foi enviado question\u00e1rio abrangendo diversos aspectos da doen\u00e7a. RESULTADOS: Dos 506 associados, 145 (28,7%) foram inclu\u00eddos no estudo - todos cel\u00edacos confirmados por biopsia. Suas idades variaram entre 3,3 e 82,5 anos (m\u00e9dia de 30,8 anos). A maioria era do sexo feminino (propor\u00e7\u00e3o de 2 mulheres para 1 homem). A idade m\u00e9dia ao diagn\u00f3stico foi de 16 anos para os homens e 26,7 para as mulheres. Os principais sintomas relatados foram distens\u00e3o abdominal (71,8%), dor abdominal (71%) e diarr\u00e9ia (65,5%). No sexo masculino, predominaram diarr\u00e9ia e d\u00e9ficit ponderal enquanto que no sexo feminino aftas, constipa\u00e7\u00e3o e anemia. Apenas 42,1% dos associados foram submetidos a biopsia em momento compat\u00edvel com o diagn\u00f3stico correto de doen\u00e7a cel\u00edaca (44,2% relataram biopsia somente em vig\u00eancia de dieta j\u00e1 isenta de gl\u00faten e 11,7% n\u00e3o souberam informar). Quanto aos testes sorol\u00f3gicos, 61,4% realizaram pelo menos um teste. Doen\u00e7as associadas ou complica\u00e7\u00f5es foram relatadas por 65,5%; dessas, a mais freq\u00fcente foi a intoler\u00e2ncia \u00e0 lactose (33%). Suplementa\u00e7\u00e3o vitam\u00ednica ou mineral foi indicada em 45% dos casos e 35,2% foram submetidos a densitometria \u00f3ssea. Desses, 59% relataram um resultado alterado (osteopenia ou osteoporose). CONCLUS\u00d5ES: Os resultados apontam para uma tend\u00eancia de diagn\u00f3stico da doen\u00e7a cel\u00edaca em idades mais avan\u00e7adas em nosso meio, especialmente entre as mulheres, e sugerem a necessidade de maiores esclarecimentos do p\u00fablico em geral e da classe m\u00e9dica quanto ao seu correto diagn\u00f3stico e tratamento.<\/jats:p>","DOI":"10.1590\/s0004-28032007000300015","type":"journal-article","created":{"date-parts":[[2007,11,28]],"date-time":"2007-11-28T18:02:32Z","timestamp":1196272952000},"page":"257-265","source":"Crossref","is-referenced-by-count":2,"title":["Perfil cl\u00ednico dos membros da associa\u00e7\u00e3o dos cel\u00edacos do Brasil: regional de Santa Catarina (ACELBRA-SC)"],"prefix":"10.1590","volume":"44","author":[{"given":"Clarissa Araujo","family":"Cassol","sequence":"first","affiliation":[{"name":"Universidade Federal de Santa Catarina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christine Prim De","family":"Pellegrin","sequence":"additional","affiliation":[{"name":"Universidade Federal de Santa Catarina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M\u00f4nica Lisboa Chang","family":"Wahys","sequence":"additional","affiliation":[{"name":"Universidade Federal de Santa Catarina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria Marlene de Souza","family":"Pires","sequence":"additional","affiliation":[{"name":"Universidade Federal de Santa Catarina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Silvia Modesto","family":"Nassar","sequence":"additional","affiliation":[{"name":"Universidade Federal de Santa Catarina"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"530","reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1016\/j.dld.2004.12.003","article-title":"Celiac disease and depression: two related entities?","volume":"37","author":"Accomando 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