{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,3,26]],"date-time":"2025-03-26T17:45:02Z","timestamp":1743011102494},"reference-count":30,"publisher":"FapUNIFESP (SciELO)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arq. Gastroenterol."],"published-print":{"date-parts":[[2007,12]]},"abstract":"<jats:p>RACIONAL: A \u00falcera duodenal sempre representou uma doen\u00e7a muito prevalente entre as enfermidades digestivas, em qualquer parte do mundo. A preval\u00eancia m\u00e9dia era de aproximadamente 10% da popula\u00e7\u00e3o mundial. A partir do in\u00edcio dos anos 90, a literatura, tanto europ\u00e9ia como norte-americana, passou a demonstrar sua redu\u00e7\u00e3o gradativa entre seus pa\u00edses. OBJETIVO: Demonstrar, atrav\u00e9s de an\u00e1lise retrospectiva, a preval\u00eancia anual da \u00falcera duodenal nos \u00faltimos 10 anos em um Servi\u00e7o de Endoscopia Digestiva que \u00e9 refer\u00eancia para o sistema p\u00fablico de sa\u00fade da cidade de Porto Alegre, munic\u00edpios da Grande Porto Alegre e outras cidades vizinhas da mesma. Os dados analisados s\u00e3o de mar\u00e7o de 1996 at\u00e9 dezembro de 2005. M\u00c9TODOS: Estudo retrospectivo transversal, com an\u00e1lise documental de diagn\u00f3sticos endosc\u00f3picos efetuados em endoscopia digestiva alta, no referido Servi\u00e7o. Foi feita a an\u00e1lise retrospectiva de diagn\u00f3sticos endosc\u00f3picos efetuados em 13.130 pacientes submetidos a endoscopia digestiva alta no per\u00edodo de mar\u00e7o de 1996 a dezembro de 2005. A classifica\u00e7\u00e3o de Sakita foi utilizada para o est\u00e1dio do grau evolutivo da \u00falcera duodenal e foi considerado por ela acometido o paciente com a les\u00e3o no est\u00e1gio A1, at\u00e9 o est\u00e1gio S1, inclusive. Observou-se tamb\u00e9m a preval\u00eancia nos dois sexos, na ra\u00e7a, o percentual m\u00e9dio total nos 10 anos, al\u00e9m da preval\u00eancia anual. Para verificar se houve signific\u00e2ncia estat\u00edstica dos resultados observados nos diferentes per\u00edodos, foi aplicado um teste de regress\u00e3o linear (\"linear regression model\"). RESULTADOS: Observou-se decr\u00e9scimo gradativo dos percentuais de preval\u00eancia da \u00falcera duodenal, ano ap\u00f3s ano, iniciando-se em 1996 com 8,6% e se encerrando no final de 2005, com 3,3%. A exce\u00e7\u00e3o do per\u00edodo foi observada no ano de 2003 quando houve um acr\u00e9scimo, comparando-se com o decr\u00e9scimo gradativo dos 6 anos anteriores. Mas j\u00e1, a partir do per\u00edodo seguinte (2004), a queda gradativa voltou a ser observada. O valor m\u00e9dio de queda anual, aplicando o teste de regress\u00e3o linear, foi da ordem de 1,3% ao ano, no per\u00edodo analisado (10 anos). Este teste mostrou tamb\u00e9m signific\u00e2ncia estat\u00edstica. A ra\u00e7a branca representou a maioria, com 78% dos pacientes, em rela\u00e7\u00e3o a ra\u00e7a negra. O sexo masculino, em todos os per\u00edodos analisados, exceto em um (1997), foi o sexo mais acometido, com uma rela\u00e7\u00e3o final masculino\/feminino da ordem de 1.17\/1.0. CONCLUS\u00d5ES: Observou-se ent\u00e3o, neste estudo efetuado no Brasil, tamb\u00e9m uma redu\u00e7\u00e3o da preval\u00eancia da \u00falcera duodenal, j\u00e1 apontada pela literatura em outros pa\u00edses. Estudos posteriores devem ser efetuados no sentido de apontar as raz\u00f5es desta importante observa\u00e7\u00e3o.<\/jats:p>","DOI":"10.1590\/s0004-28032007000400008","type":"journal-article","created":{"date-parts":[[2008,2,21]],"date-time":"2008-02-21T00:17:33Z","timestamp":1203553053000},"page":"320-324","source":"Crossref","is-referenced-by-count":12,"title":["Redu\u00e7\u00e3o da preval\u00eancia de \u00falcera duodenal: um estudo brasileiro (an\u00e1lise retrospectiva na \u00faltima d\u00e9cada: 1996-2005)"],"prefix":"10.1590","volume":"44","author":[{"given":"Carlos","family":"Saul","sequence":"first","affiliation":[{"name":"Universidade Federal de Pelotas"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cl\u00e1udio Rolim","family":"Teixeira","sequence":"additional","affiliation":[{"name":"Funda\u00e7\u00e3o Riograndense Universit\u00e1ria de Gastroenterologia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julio C.","family":"Pereira-Lima","sequence":"additional","affiliation":[{"name":"Funda\u00e7\u00e3o Federal Faculdade de Ci\u00eancias M\u00e9dicas"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ronaldo J. Spinatto","family":"Torresini","sequence":"additional","affiliation":[{"name":"Funda\u00e7\u00e3o Riograndense Universit\u00e1ria de Gastroenterologia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"530","reference":[{"key":"ref1","first-page":"cr554","article-title":"Incidence of complications of peptic ulcers in patients with H.pylori infection and\/or NSAID use in the era of Hp eradication","volume":"8","author":"Bobrzynski A","year":"2002","journal-title":"Med Sci Monit."},{"key":"ref2","doi-asserted-by":"crossref","first-page":"933","DOI":"10.1016\/S0140-6736(02)11030-0","article-title":"Peptic-ulcer disease","volume":"360","author":"Chan FK","year":"2002","journal-title":"Lancet","ISSN":"http:\/\/id.crossref.org\/issn\/0099-5355","issn-type":"print"},{"issue":"6","key":"ref3","doi-asserted-by":"crossref","first-page":"1365","DOI":"10.3748\/wjg.v9.i6.1365","article-title":"Prevalence of anti-ulcer drug use in a Chinese cohort","author":"Chen 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