{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,9]],"date-time":"2025-05-09T22:24:05Z","timestamp":1746829445861},"reference-count":19,"publisher":"FapUNIFESP (SciELO)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arq. Gastroenterol."],"published-print":{"date-parts":[[2008,12]]},"abstract":"<jats:p>RACIONAL: Na cirurgia geral, as corre\u00e7\u00f5es das h\u00e9rnias da parede abdominal ocupam lugar de destaque e, cada vez mais, as indica\u00e7\u00f5es e usos de telas t\u00eam aumentado devido aos melhores resultados. OBJETIVO: Comparar as corre\u00e7\u00f5es de orif\u00edcios produzidos em parede abdominal com telas Parietex\u00ae e Surgisis\u00ae em contato direto com as v\u00edsceras abdominais. M\u00c9TODO: Para os experimentos foram utilizadas 16 coelhas adultas jovens e produ\u00e7\u00e3o de defeitos triangulares de 2 cm de base por 2,5 cm de altura, comprometendo os planos m\u00fasculo-aponeur\u00f3tico-peritoniais da parede abdominal, nos flancos, sim\u00e9tricos \u00e0 linha m\u00e9dia que foram corrigidos com telas retangulares de 3 cm de base por 3,5 cm de altura. No lado direito usou-se tela Parietex\u00ae (poli\u00e9ster\/col\u00e1geno-polietilenoglicol-glicerol) e no lado esquerdo tela Surgisis\u00ae (submucosa intestinal su\u00edna). Na avalia\u00e7\u00e3o utilizaram-se par\u00e2metros cl\u00ednico-cir\u00fargicos, histol\u00f3gicos e imunoistoqu\u00edmicos. Oito coelhas foram submetidas a eutan\u00e1sia em 30 dias e as 8 restantes, em 60. Comparou-se a efici\u00eancia das duas telas. RESULTADOS: As duas telas provocaram eros\u00f5es de pele e n\u00e3o ocorreu nenhum caso de h\u00e9rnia incisional. As ader\u00eancias ocorreram em todas as telas no primeiro m\u00eas e em menor grau e intensidade, no segundo m\u00eas; a retra\u00e7\u00e3o delas foi de 1\/3 do tamanho original; a Parietex\u00ae provocou menor processo inflamat\u00f3rio; n\u00e3o houve diferen\u00e7a significante de deposi\u00e7\u00e3o de entre as duas telas; a deposi\u00e7\u00e3o do col\u00e1geno tipo III foi mais intensa no segundo m\u00eas em ambas; na remodela\u00e7\u00e3o do col\u00e1geno a produ\u00e7\u00e3o da enzima MMP8 foi maior na tela Parietex\u00ae no primeiro m\u00eas e a enzima MMP13 aumentou no segundo m\u00eas em ambas as telas, por\u00e9m com signific\u00e2ncia apenas na Parietex\u00ae. CONCLUS\u00c3O: As duas telas foram eficientes na corre\u00e7\u00e3o de h\u00e9rnias incisionais e com resultados semelhantes, sendo que a Parietex\u00ae apresentou menor processo inflamat\u00f3rio, maior quantidade de metaloproteinases MMP8 e MMP13 em rela\u00e7\u00e3o \u00e0 Surgisis\u00ae.<\/jats:p>","DOI":"10.1590\/s0004-28032008000400012","type":"journal-article","created":{"date-parts":[[2009,1,14]],"date-time":"2009-01-14T19:09:52Z","timestamp":1231960192000},"page":"323-329","source":"Crossref","is-referenced-by-count":8,"title":["O uso de telas Parietex\u00ae e Surgisis\u00ae na corre\u00e7\u00e3o de defeitos produzidos na parede abdominal de coelhos"],"prefix":"10.1590","volume":"45","author":[{"given":"Jo\u00e3o Batista","family":"Baroncello","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicolau 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