{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,13]],"date-time":"2026-11-13T10:03:58Z","timestamp":1794564238120,"version":"4.9.1"},"reference-count":34,"publisher":"FapUNIFESP (SciELO)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arq. Gastroenterol."],"published-print":{"date-parts":[[2010,3]]},"abstract":"<jats:p>CONTEXT: Cirrhosis, diabetes mellitus, impaired glucose tolerance, insulin resistance, and protein calorie malnutrition are important issues in cirrhotic patients because they can increase the progression of liver disease and worsen its prognosis. OBJECTIVE:To determine the prevalence of diabetes mellitus, impaired glucose tolerance and insulin resistance in cirrhotic patients being evaluated for liver transplantation and their impacts on a 3-month follow-up, and to compare fasting glycemia and oral glucose tolerance test. METHODS: A cross-sectional study was performed in consecutively included adult patients. Diabetes mellitus was established through fasting glycemia and oral glucose tolerance test in diagnosing diabetes mellitus in this population. HOMA-IR and HOMA-\u03b2 indexes were calculated, and nutritional assessment was performed by subjective global assessment, anthropometry and handgrip strength through dynamometry. RESULTS: Diabetes mellitus was found in 40 patients (64.5%), 9 (22.5%) of them by fasting glycemia and 31 (77.5%) of them by oral glucose tolerance test. Insulin resistance was found in 40 (69%) of the patients. There was no relationship between diabetes mellitus and the etiology of cirrhosis. Protein calorie malnutrition was diagnosed in a range from 3.22% to 45.2% by anthropometry, 58.1% by subjective global assessment and 88.7% by handgrip strength. Diabetes mellitus identified by oral glucose tolerance test was related significantly to a higher prevalence of infectious complications and deaths in a 3-month period (P = 0.017). CONCLUSION: The prevalence of diabetes mellitus, impaired glucose tolerance, insulin resistance and protein calorie malnutrition is high in cirrhotic patients on the waiting list for liver transplantation. There were more infectious complications and\/or deaths in a 3-month follow-up period in patients with diabetes mellitus diagnosed by oral glucose tolerance test. Oral glucose tolerance test seems to be indicated as a routine practice in this population.<\/jats:p>","DOI":"10.1590\/s0004-28032010000100005","type":"journal-article","created":{"date-parts":[[2017,3,31]],"date-time":"2017-03-31T22:29:30Z","timestamp":1490999370000},"page":"22-27","source":"Crossref","is-referenced-by-count":20,"title":["Prevalence of diabetes mellitus and impaired glucose tolerance in patients with decompensated cirrhosis being evaluated for liver transplantation: the utility of oral glucose tolerance test"],"prefix":"10.1590","volume":"47","author":[{"given":"Ana Carolina Costa","family":"Bragan\u00e7a","sequence":"first","affiliation":[{"name":"Universidade Federal do Rio Grande do Sul"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M\u00e1rio Reis","family":"\u00c1lvares-da-Silva","sequence":"additional","affiliation":[{"name":"UFRGS, Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"530","reference":[{"key":"ref1","series-title":"Compara\u00e7\u00e3o entre a avalia\u00e7\u00e3o nutricional subjetiva global, \u00edndice progn\u00f3stico e for\u00e7a do aperto de m\u00e3o n\u00e3o-dominante na avalia\u00e7\u00e3o nutricional do paciente cirr\u00f3tico ambulatorial: a contribui\u00e7\u00e3o da dinamometria","author":"\u00c1lvares-da-Silva MR"},{"key":"ref2","first-page":"746(A)","article-title":"Nutritional evaluation in liver transplantation","volume":"28","author":"\u00c1lvares-da-Silva MR","year":"1998","journal-title":"Hepatology."},{"key":"ref3","first-page":"203","article-title":"Non-dominant handgrip strength study in healthy individuals","volume":"17","author":"\u00c1lvares-da-Silva MR","year":"1998","journal-title":"Determinations of reference values to be used in dynamometry. 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