{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T17:29:00Z","timestamp":1777915740718,"version":"3.51.4"},"reference-count":39,"publisher":"FapUNIFESP (SciELO)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arq. Gastroenterol."],"published-print":{"date-parts":[[2011,12]]},"abstract":"<jats:p>CONTEXT: Although the high incidence of gastroesophageal reflux disease (GERD) in the population, there is much controversy in this topic, especially in the surgical treatment. The decision to use of a total or partial fundoplication in the treatment of GERD is still a challenge to many surgeons because the few evidence found in the literature. OBJECTIVE: To bring more clear evidence in the comparison between total and partial fundoplication. DATA SOURCES: A systematic review of the literature and metaanalysis with randomized controlled trials accessed from MEDLINE, LILACS, Cochrane Controlled Trials Database was done. The outcomes remarked were: dysphagia, inability to belch, bloating, recurrence of acid reflux, heartburn and esophagitis. For data analysis the odds ratio was used with corresponding 95% confidence interval. Statistical heterogeneity in the results of the metaanalysis was assessed by calculating a test of heterogeneity. The software Review Manager 5 (Cochrane Collaboration) was utilized for the data gathered and the statistical analysis. Sensitive analysis was applied using only trials that included follow-up over 2 years. RESULTS: Ten trials were included with 1003 patients: 502 to total fundoplication group and 501 to partial fundoplication group. The outcomes dysphagia and inability to belch had statistical significant difference (P = 0.00001) in favor of partial fundoplication. There was not statistical difference in outcomes related with treatment failure. There were no heterogeneity in the outcomes dysphagia and recurrence of the acid reflux. CONCLUSION: The partial fundoplication has lower incidence of obstructive side effects.<\/jats:p>","DOI":"10.1590\/s0004-28032011000400007","type":"journal-article","created":{"date-parts":[[2017,3,31]],"date-time":"2017-03-31T20:33:33Z","timestamp":1490992413000},"page":"252-260","source":"Crossref","is-referenced-by-count":16,"title":["Surgical treatment of gastroesophageal reflux disease: total or partial fundoplication? Systematic review and meta-analysis"],"prefix":"10.1590","volume":"48","author":[{"given":"Rodrigo F","family":"Ramos","sequence":"first","affiliation":[{"name":"Universidade Federal Fluminense"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Suzana Ang\u00e9lica S","family":"Lustosa","sequence":"additional","affiliation":[{"name":"Hospital Munir Rafful"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carlos Augusto P. de","family":"Almeida","sequence":"additional","affiliation":[{"name":"Faculdade de Medicina de Volta Redonda"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carolina P. da","family":"Silva","sequence":"additional","affiliation":[{"name":"Faculdade de Medicina de Volta Redonda"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Delcio","family":"Matos","sequence":"additional","affiliation":[{"name":"Universidade Federal de S\u00e3o Paulo,  Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"530","reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"819","DOI":"10.1002\/bjs.4803","article-title":"Randomized double-blind trial of laparoscopic Nissen fundoplication versus anterior partial fundoplication","volume":"92","author":"Baigrie RJ","year":"2005","journal-title":"Br J Surg","ISSN":"https:\/\/id.crossref.org\/issn\/0007-1323","issn-type":"print"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"1189","DOI":"10.1007\/PL00009618","article-title":"patterns of success and failure with laparoscopic Toupet fundoplication","volume":"13","author":"Bell RC","year":"1999","journal-title":"Surg Endosc","ISSN":"https:\/\/id.crossref.org\/issn\/0930-2794","issn-type":"print"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1002\/bjs.6047","article-title":"Randomized clinical trial of laparoscopic total (Nissen) versus posterior partial (Toupet) fundoplication for 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