{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,3,31]],"date-time":"2022-03-31T05:08:41Z","timestamp":1648703321876},"reference-count":38,"publisher":"FapUNIFESP (SciELO)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arq. Gastroenterol."],"published-print":{"date-parts":[[2012,6]]},"abstract":"<jats:p>CONTEXT: Stomach cancer is the second leading cause of death due to cancer in the world and the incidence of this disease continues to be high in Brazil. In the Northern region, gastric cancer is the second most frequent cancer among men and the third among women. In the State of Par\u00e1, stomach adenocarcinoma is a public health problem since mortality rates are above the Brazilian average. OBJECTIVE: To analyze the clinical and anatomopathological profile of stomach adenocarcinoma in patients seen at Ofir Loiola Hospital. METHODS: In a retrospective study, records from 302 patients with gastric cancer undergoing surgery between 2006 and 2008 were analyzed. Data regarding patient profile, early symptoms, alterations upon physical examination, type of surgery, and macroscopic and histological findings were obtained from the records. RESULTS: Most patients (63.9%) were men, 48% were older than 60 years, 50.9% were from the metropolitan region of Bel\u00e9m, 68.2% presented epigastric pain as an early symptom, and abdominal tenderness upon palpation was observed in 63.7%. The antrum was the most affected anatomical site (62.1%), followed by the gastric body (26.9%). Borrmann III (ulcerated-infiltrative) was the predominant endoscopic type. Adenocarcinoma accounted for 95.4% of all cases, including the intestinal type in 56.6% and the diffuse type in 41.3%. Most patients had stage IIIB and IV tumors and total gastrectomy was the most frequent type of surgery (37.4%). CONCLUSION: The present study demonstrated that gastric adenocarcinoma mainly affected men over the age of 60 who were from the metropolitan region of Bel\u00e9m. Most adenocarcinomas were in an advanced stage at the time of diagnosis, a fact requiring more aggressive surgical resection in these cases. These data highlight the urgent need for the implementation of preventive measures and early detection programs of gastric cancer.<\/jats:p>","DOI":"10.1590\/s0004-28032012000200006","type":"journal-article","created":{"date-parts":[[2012,7,4]],"date-time":"2012-07-04T22:47:21Z","timestamp":1341442041000},"page":"125-129","source":"Crossref","is-referenced-by-count":3,"title":["Case study of stomach adenocarcinoma conducted at a cancer referral hospital in northern Brazil"],"prefix":"10.1590","volume":"49","author":[{"given":"Ruth Maria Dias Ferreira","family":"Vinagre","sequence":"first","affiliation":[{"name":"State University of Par\u00e1"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brenda Prazeres de","family":"Campos","sequence":"additional","affiliation":[{"name":"State University of Par\u00e1, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rachid Marwan Pinheiro","family":"Sousa","sequence":"additional","affiliation":[{"name":"State University of Par\u00e1, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"530","reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1590\/S0004-28032006000400009","article-title":"Prevalence of Helicobacter pylori infection in advanced gastric carcinoma","volume":"43","author":"Ara\u00fajo Filho I","year":"2006","journal-title":"Arq Gastroenterol","ISSN":"http:\/\/id.crossref.org\/issn\/0004-2803","issn-type":"print"},{"key":"ref2","series-title":"Bioestat 5.0: Aplica\u00e7\u00f5es estat\u00edsticas nas \u00e1reas das ci\u00eancias biol\u00f3gicas e m\u00e9dicas","first-page":"364","author":"Ayres M","year":"2007"},{"key":"ref3","first-page":"400","article-title":"Grupo sangu\u00edneo A y riesgo de c\u00e2ncer g\u00e1strico en el hospital universit\u00e1rio de Santander (Bucaramanga, Col\u00f4mbia)","volume":"31","author":"Berm\u00fadez C","year":"2006","journal-title":"Acta M\u00e9d Colomb"},{"key":"ref4","first-page":"112","article-title":"C\u00e2ncer g\u00e1strico: um estudo no hospital universit\u00e1rio Walter Cant\u00eddio","volume":"41","author":"Botelho PN","year":"2001","journal-title":"Rev Med UFC"},{"key":"ref5","first-page":"7","article-title":"Stomach cancer: risk factors","volume":"13","author":"Britto AV","year":"1997","journal-title":"Cad Sa\u00fade P\u00fablica"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"5962","DOI":"10.3748\/wjg.14.5962","article-title":"MYC and gastric adenocarcinoma carcinogenesis","volume":"14","author":"Calcagno DQ","year":"2008","journal-title":"World J Gastroenterol"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1590\/S0004-28032007000300014","article-title":"Endoscopic mucosal resection of early gastric cancer: initial experience with two technical variants","volume":"44","author":"Campoli PM","year":"2007","journal-title":"Arq Gastroenterol","ISSN":"http:\/\/id.crossref.org\/issn\/0004-2803","issn-type":"print"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"211","DOI":"10.32635\/2176-9745.RBC.2004v50n3.2025","article-title":"C\u00e2ncer g\u00e1strico em idosos","volume":"50","author":"Costa PB","year":"2004","journal-title":"Rev Bras Cancerol","ISSN":"http:\/\/id.crossref.org\/issn\/0034-7116","issn-type":"print"},{"key":"ref9","series-title":"C\u00e2ncer g\u00e1strico: estudo retrospectivo de 313 casos no Ophir Loyola no per\u00edodo de 1994 a 1998","author":"Dias MBC","year":"1999"},{"key":"ref10","series-title":"AJCC cancer staging manual","author":"Greene FL","year":"2002","edition":"6"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1590\/S0104-42302006000400030","article-title":"Linfadenectomia no adenocarcinoma g\u00e1strico","volume":"52","author":"Ilias EJ","year":"2006","journal-title":"Rev Assoc Med Bras","ISSN":"http:\/\/id.crossref.org\/issn\/0004-5241","issn-type":"print"},{"key":"ref12","series-title":"Estimativas 2008: incid\u00eancia de c\u00e2ncer no Brasil","year":"2007"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1590\/S0104-42302003000300015","article-title":"Epidemiologia do c\u00e2ncer g\u00e1strico","volume":"49","author":"Kassab P","year":"2003","journal-title":"Rev Assoc Med Bras","ISSN":"http:\/\/id.crossref.org\/issn\/0004-5241","issn-type":"print"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1590\/S0102-311X1997000500009","article-title":"Stomach cancer incidence in Brazil: an ecologic study with selected risk factors","volume":"13","author":"Koifman S","year":"1997","journal-title":"Cad Sa\u00fade Publica"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1111\/apm.1965.64.1.31","article-title":"The two histological types of gastric carcinoma: diffuse and so-called intestinal-type carcinoma. 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