{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,18]],"date-time":"2025-04-18T15:25:24Z","timestamp":1744989924192},"reference-count":9,"publisher":"FapUNIFESP (SciELO)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arq. Gastroenterol."],"published-print":{"date-parts":[[2013,4]]},"abstract":"<jats:p> Context Liver transplantation has been accepted as a therapeutic option for patients with end-stage liver disease and acute liver failure. Currently, Brazil has a well-established public organ transplant program, performing 7,425 solid organs transplants in 2012 alone, among which 1,595 were liver transplants. Jehovah's Witnesses report 7,6 million members worldwide. For religious reasons they refuse transfusion of whole blood or its primary components (red cells, fresh frozen plasma, platelets).   Objective This study aims to present the results obtained with Jehovah's Witnesses patients by a liver transplantation service.   Method We conducted a retrospective review of medical records from Jehovah's Witnesses patients (n = 4) who underwent orthotopic liver transplantation from September 2009 to September 2011 at the Walter Cant\u00eddio University Hospital of the Federal University of Cear\u00e1, Fortaleza, CE, Brazil. Coagulation parameters such as Hemoglobin, Hematocrit, Platelets, INR were evaluated during the preoperative, immediate postoperative, postoperative day (POD) 7 and POD 30.   Results Coagulation parameters were expressed as means: hematocrit, 35.07% \u00b1 6.65%, 24.6% \u00b1 4.74%, 19.85% \u00b1 2.10%, 31.85% \u00b1 5.99%; hemoglobin, 12.57 g\/dL \u00b1 2.22, 8.92 g\/dL \u00b1 1.75, 6.92 g\/dL \u00b1 0.58, 11.17 g\/dL \u00b1 0.9; platelets, 160,975 mm 3  \u00b1 148000, 128,000 mm 3  \u00b1 34836, 65,000 mm 3  \u00b1 33496, 234,250 mm 3  \u00b1 287003 and INR, 143 \u00b1 0.10, 2.4 \u00b1 0.34, 1.24 \u00b1 0.10, 1.14 \u00b1 0.09.   Conclusion Liver transplantation can successfully be performed in Jehovah's Witnesses patient population provided that: 1) the medical team has extensive expertise in that field, 2) the patient has an adequate level of hematologic factors preoperatively, and 3) there is availability of specialized equipment such as cell saver to minimize blood loss and thus avoid transfusion requirements.<\/jats:p>","DOI":"10.1590\/s0004-28032013000200023","type":"journal-article","created":{"date-parts":[[2013,7,23]],"date-time":"2013-07-23T17:01:27Z","timestamp":1374598887000},"page":"138-140","source":"Crossref","is-referenced-by-count":9,"title":["LIVER TRANSPLANTATION IN JEHOVAH'S WITNESSES PATIENTS IN A CENTER OF NORTHEASTERN BRAZIL"],"prefix":"10.1590","volume":"50","author":[{"given":"Jos\u00e9 Huygens Parente","family":"GARCIA","sequence":"first","affiliation":[{"name":"Federal University of Cear\u00e1,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gustavo Rego","family":"COELHO","sequence":"additional","affiliation":[{"name":"Federal University of Cear\u00e1,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bartolomeu Alves","family":"FEITOSA NETO","sequence":"additional","affiliation":[{"name":"Federal University of Cear\u00e1,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emmanuel Almeida","family":"NOGUEIRA","sequence":"additional","affiliation":[{"name":"Federal University of Cear\u00e1,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cayo C\u00e9sar G\u00f3is","family":"TEIXEIRA","sequence":"additional","affiliation":[{"name":"Federal University of Cear\u00e1,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Denissa Ferreira Gomes","family":"MESQUITA","sequence":"additional","affiliation":[{"name":"Federal University of Cear\u00e1,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"530","reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1093\/bja\/aeq244","article-title":"Cell salvage as part of a blood conservation strategy in anaesthesia","volume":"105","author":"Ashworth A; Klein AA","year":"2010","journal-title":"Br J Anaesth"},{"key":"ref2","year":"1988"},{"key":"ref3","first-page":"1","year":"Feb"},{"key":"ref4","first-page":"326","article-title":"Liver transplant in Jehovah's Witnesses patients. Current Opinion in Organ Transplantation","volume":"2011","author":"Darwish A","journal-title":"jun"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"929","DOI":"10.1111\/j.1432-2277.2005.00160.x","article-title":"Liver transplantation in Jehovah's Witnesses","volume":"18","author":"Detry O","year":"2005","journal-title":"Transpl Int"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1097\/01.sla.0000133352.25163.fd","article-title":"Live donor liver transplantation without blood products: strategies developed for Jehovah's Witnesses offer broad application","volume":"240","author":"Jabbour N","year":"2004","journal-title":"Ann Surg"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1016\/j.jamcollsurg.2005.04.006","article-title":"Transfusion free surgery: single institution experience of 27 consecutive liver transplants in Jehovah's Witnesses","volume":"201","author":"Jabbour N","year":"2005","journal-title":"J Am Coll Surg"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"861","DOI":"10.1016\/j.mcna.2008.03.008","article-title":"Liver transplantation: indications, pretransplant evaluation, surgery, and posttransplant complications","volume":"92","author":"Koffron A","year":"2008","journal-title":"Med Clin North Am"},{"key":"ref9","first-page":"1","year":"2012"}],"container-title":["Arquivos de Gastroenterologia"],"original-title":[],"link":[{"URL":"http:\/\/www.scielo.br\/pdf\/ag\/v50n2\/0004-2803-ag-50-02-138.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,5,27]],"date-time":"2017-05-27T15:00:45Z","timestamp":1495897245000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.scielo.br\/scielo.php?script=sci_arttext&pid=S0004-28032013000200138&lng=en&tlng=en"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,4]]},"references-count":9,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2013,4]]}},"alternative-id":["S0004-28032013000200138"],"URL":"https:\/\/doi.org\/10.1590\/s0004-28032013000200023","relation":{},"ISSN":["0004-2803"],"issn-type":[{"value":"0004-2803","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,4]]}}}