{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,8,18]],"date-time":"2023-08-18T18:30:45Z","timestamp":1692383445656},"reference-count":21,"publisher":"FapUNIFESP (SciELO)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arq. Gastroenterol."],"published-print":{"date-parts":[[2013,4]]},"abstract":"<jats:p> Context Data on vascular alterations in patients with hepatosplenic schistosomiasis and portal hypertensive colopathy and changes in these after surgery to decrease portal hypertension are limited.   Objective The purpose of this study was to analyse the alterations of portal hypertensive colopathy previously and 6-12 months after splenectomy and gastric devascularization.   Methods Twelve patients with hepatosplenic schistosomiasis who also had upper gastrointestinal bleeding were studied prospectively. Their endoscopic findings before and 6-12 months after the surgery were analysed. In addition, mucosal biopsies from ascending colon, sigmoid colon and rectum at these time points were subjected to histological and histomorphometric assessment. It was used a control group due to lack of normal pattern of the histomorphometric measures of vessels in individuals without portal hypertension. The critical level of significance adopted in all tests was of a maximum probability error of 5%.   Results Surgery did not lead to significant improvement in histological and endoscopic findings. However, on histomorphometry, there was a significant decrease in the area, diameter and thickness of the vessels in mucosa at all colonic sites.   Conclusion Surgery for decompression of schistosomal portal hypertension has a beneficial effect on the associated colopathy, being best indicated in patients with gastrointestinal bleeding and esophageal varices.<\/jats:p>","DOI":"10.1590\/s0004-28032013000200026","type":"journal-article","created":{"date-parts":[[2013,7,23]],"date-time":"2013-07-23T21:01:32Z","timestamp":1374613292000},"page":"153-156","source":"Crossref","is-referenced-by-count":3,"title":["IMPROVEMENT OF SCHISTOSOMAL PORTAL HYPERTENSIVE COLOPATHY AFTER SURGICAL TREATMENT"],"prefix":"10.1590","volume":"50","author":[{"given":"Maria Angelina Carvalho","family":"MIRANDA","sequence":"first","affiliation":[{"name":"Universidade Federal de Pernambuco (UFPE)"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u00c1lvaro Ant\u00f4nio Bandeira","family":"FERRAZ","sequence":"additional","affiliation":[{"name":"Universidade Federal de Pernambuco (UFPE)"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana L\u00facia Coutinho","family":"DOMINGUES","sequence":"additional","affiliation":[{"name":"UFPE,  Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Renata Carvalho Miranda","family":"CHAVES","sequence":"additional","affiliation":[{"name":"UFPE,  Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Norma","family":"JUC\u00c1","sequence":"additional","affiliation":[{"name":"Universidade de S\u00e3o Paulo,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Di\u00f3genes Luiz da","family":"MOTA","sequence":"additional","affiliation":[{"name":"UFPE,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"530","reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"1166","DOI":"10.3748\/wjg.v18.i11.1166","article-title":"Treatment of portal hypertension","volume":"18","author":"Bari K","year":"2012","journal-title":"World J Gastroenterol"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1067\/mge.2000.108478","article-title":"Mucosal abnormalities of the colon in patients with portal hypertension: an endoscopic study","volume":"52","author":"Bini EJ","year":"2000","journal-title":"Gastrointest Endosc"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"5471","DOI":"10.3748\/wjg.v13.i41.5471","article-title":"Pre and postoperative systemic hemodynamic evaluation in patients subjected to esophagogastric devascularization plus splenectomy and distal splenorenal shunt: a comparative study in schistosomal portal hypertension","volume":"13","author":"de Cleva R","year":"2007","journal-title":"World J Gastroenterol"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"4781","DOI":"10.3748\/wjg.15.4781","article-title":"Portal hypertensive colopathy is associated with portal hypertension severity in cirrhotic patients","volume":"15","author":"Diaz-Sanches A","year":"2009","journal-title":"World J Gastroenterol"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1590\/S0004-28032003000100002","article-title":"The influence of periportal (pipestem) fibrosis on long term results of surgical treatment for schistosomotic portal hypertension","volume":"40","author":"Ferraz AA","year":"2003","journal-title":"Arq Gastroenterol"},{"key":"ref6","first-page":"1","article-title":"Surgical Treatment of Schistosomal Portal Hypertension","volume":"86","author":"Ferraz AA","year":"2001","journal-title":"Int Surg"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1016\/j.ajg.2011.11.002","article-title":"Portal hypertensive colopathy and haematochezia in cirrhotic patients: na endoscopic study","volume":"12","author":"Gad YZ","year":"2011","journal-title":"Arab J Gastroenterol"},{"key":"ref8","first-page":"343","article-title":"Vascular alterations of the colonic mucosa in schistosomiasis and portal colopathy","volume":"42","author":"Geboes K","year":"1995","journal-title":"Hepatogastroenterology"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"332","DOI":"10.4166\/kjg.2011.58.6.332","article-title":"Endoscopic findings and clinical significance of portal hypertensive colopathy","volume":"58","author":"Jeong IB","year":"2011","journal-title":"Korean J Gastroenterol"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1590\/S0102-86502005000100003","article-title":"Effect of splenectomy and ligature of the left gastric vein on portal hypertensive colopathy in carriers of surgical hepatosplenic schistosomiasis mansoni","volume":"20","author":"Justo CR","year":"2005","journal-title":"Acta Cir Bras"},{"key":"ref11","first-page":"2743","author":"Kalafateli M","year":"2012"},{"key":"ref12","first-page":"357","article-title":"Critical evaluation of schistosomotic portal hypertension surgery. 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