{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,4,3]],"date-time":"2022-04-03T12:14:48Z","timestamp":1648988088604},"reference-count":18,"publisher":"FapUNIFESP (SciELO)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arq. Neuro-Psiquiatr."],"published-print":{"date-parts":[[1971,9]]},"abstract":"<jats:p>As modifica\u00e7\u00f5es dos quadros cl\u00ednico e EEG foram estudadas em 9 pacientes com manifesta\u00e7\u00f5es epil\u00e9pticas rebeldes \u00e0s medica\u00e7\u00f5es anticonvulsivantes habituais, quando submetidos \u00e0 administra\u00e7\u00e3o parenteral di\u00e1ria de diazepam (Valium) e ap\u00f3s sua interrup\u00e7\u00e3o. Houve diminui\u00e7\u00e3o do n\u00famero e da dura\u00e7\u00e3o das crises, superior a 75%, em tr\u00eas pacientes. Esses resultados s\u00e3o satisfat\u00f3rios, considerando a gravidade dos quadros epil\u00e9pticos e foram obtidos em pacientes com predom\u00ednio de altera\u00e7\u00f5es EEG lentas antes de iniciar o esquema terap\u00eautico. N\u00e3o se verificaram efeitos colaterais relevantes na \u00e9poca da administra\u00e7\u00e3o parenteral. Em dois pacientes foi observado o aparecimento de crises t\u00f4nicas coincidindo com o aumento de elementos EEG parox\u00edsticos r\u00e1pidos, localizados ou difusos.<\/jats:p>","DOI":"10.1590\/s0004-282x1971000300007","type":"journal-article","created":{"date-parts":[[2013,4,20]],"date-time":"2013-04-20T13:14:04Z","timestamp":1366463644000},"page":"341-349","source":"Crossref","is-referenced-by-count":2,"title":["Diazepam parenteral no tratamento de epilepsias graves"],"prefix":"10.1590","volume":"29","author":[{"given":"Jos\u00e9 Geraldo","family":"Speciali","sequence":"first","affiliation":[{"name":"Faculdade de Medicina de Ribeir\u00e3o Preto"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michel Pierre","family":"Lison","sequence":"additional","affiliation":[{"name":"Faculdade de Medicina de Ribeir\u00e3o Preto"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"530","reference":[{"key":"ref1","first-page":"471","article-title":"\u2014 Diagnostic et traitement de l'\u00e9pilepsie myoclonique progressive type Unverricht-Lundborg","volume":"68","author":"DECLERCK","year":"1968","journal-title":"Acta neurol. 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