{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T23:23:34Z","timestamp":1786749814096,"version":"build-2736575974"},"reference-count":27,"publisher":"FapUNIFESP (SciELO)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arq. Neuro-Psiquiatr."],"published-print":{"date-parts":[[1986,12]]},"abstract":"<jats:p>A s\u00edndrome de Aicardi \u00e9 caracterizada por agenesia do corpo caloso retardo mental severo, convuls\u00f5es (frequentemente espasmos em flex\u00e3o), altera\u00e7\u00f5es caracter\u00edsticas do eletrencefalograma (padr\u00e3o surto-depress\u00e3o), lacunas coriorretinianas t\u00edpicas, ocorr\u00eancia no sexo feminino. Outros achad associados s\u00e3o displasias de costelas e de v\u00e9rtebras; heterotipias corticais s\u00e3o encontradas frequentemente. A s\u00edndrome \u00e9 de natureza heredit\u00e1ria, sendo no presente considerada devida a tra\u00e7o dominante ligado ao cromossoma X, com letalidade masculina. Os autores descrevem dois casos da s\u00edndrome que mostram o quadro cl\u00ednico completo da entidade.<\/jats:p>","DOI":"10.1590\/s0004-282x1986000400007","type":"journal-article","created":{"date-parts":[[2011,7,7]],"date-time":"2011-07-07T16:35:43Z","timestamp":1310056543000},"page":"364-372","source":"Crossref","is-referenced-by-count":1,"title":["S\u00edndrome de Aicardi: relato de dois casos"],"prefix":"10.1590","volume":"44","author":[{"given":"Ronaldo","family":"Abraham","sequence":"first","affiliation":[{"name":"Universidade de Taubat\u00e9"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paulo Afonso M.","family":"Kanda","sequence":"additional","affiliation":[{"name":"Hospital Heli\u00f3polis de S\u00e3o Paulo"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luciano Jos\u00e9 Basilio da","family":"Silva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paulo de","family":"Mello","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicolau G.","family":"Segre","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"530","reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"1040","DOI":"10.1016\/S0022-3476(80)80460-4","article-title":"Aicardi syndrome in a male infant (Letter)","volume":"97","author":"AICARDI J.","year":"1980","journal-title":"J. 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