{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,8,26]],"date-time":"2023-08-26T20:14:47Z","timestamp":1693080887342},"reference-count":63,"publisher":"FapUNIFESP (SciELO)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arq. Neuro-Psiquiatr."],"published-print":{"date-parts":[[1987,9]]},"abstract":"<jats:p>Foram estudadas 371 amostras de LCR e 324 amostras de soro de 40 pacientes com diagn\u00f3stico de neurocisticercose submetidos a tratamento medicamentoso com praziquantel visando a an\u00e1lise cr\u00edtica da evolu\u00e7\u00e3o de altera\u00e7\u00f5es da imunidade humoral verificadas atrav\u00e9s da s\u00edndrome do LCR na NC. A partir dos resultados obtidos foi poss\u00edvel verificar exist\u00eancia de fatores de interfer\u00eancia complexos como os relacionados a: formas cl\u00ednicas, tempo de doen\u00e7a, corticorterapia-depend\u00eancia pr\u00e9via, deriva\u00e7\u00e3o ventricular, achados tomogr\u00e1ficos m\u00faltiplos e tratamento medicamentoso, levando todos eles a diversos graus de interfer\u00eancia na intensidade do transparecimento da s\u00edndrome do LCR na NC. Fen\u00f4menos de libera\u00e7\u00e3o de globulinas gama no sistema LCR foram verificados em 37 casos (92,5%), de maneira persistente em 18 (45%) deles, durante todas as fases do estudo e n\u00e3o sofrendo altera\u00e7\u00f5es com o tratamento medicamentoso. A interpreta\u00e7\u00e3o dos resultados deve ser sempre realizada caso a caso, devido \u00e0 grande dispers\u00e3o dos eventos e \u00e0s diferen\u00e7as de comportamento dos dados relativos \u00e0 imunidade humoral quando analisados criticamente durante dado per\u00edodo evolutivo. Estudos estat\u00edsticos de concord\u00e2ncia e correla\u00e7\u00e3o comprovaram sua evid\u00eancia para os eventos estudados quanto \u00e0 libera\u00e7\u00e3o local de globulinas gama no LCR e \u00e0 seguran\u00e7a das rea\u00e7\u00f5es imunol\u00f3gicas para cisticercose, quando reagentes. Destaca-se finalmente a import\u00e2ncia do exame do LCR que foi, \u00e9 e continuar\u00e1 sendo b\u00e1sico para o estudo da neurocisticercose.<\/jats:p>","DOI":"10.1590\/s0004-282x1987000300006","type":"journal-article","created":{"date-parts":[[2017,3,31]],"date-time":"2017-03-31T16:15:04Z","timestamp":1490976904000},"page":"261-275","source":"Crossref","is-referenced-by-count":12,"title":["S\u00edndrome do l\u00edquido cefalorraqueano na neurocisticercose: estudo cr\u00edtico sobre a evolu\u00e7\u00e3o da imunidade humoral"],"prefix":"10.1590","volume":"45","author":[{"given":"J. A.","family":"Livramento","sequence":"first","affiliation":[{"name":"USP"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"530","reference":[{"key":"ref1","first-page":"1","article-title":"Neurocisticercose: incid\u00eancia, diagn\u00f3stico e formas cl\u00ednicas","volume":"20","author":"CANELAS H.M.","year":"1962","journal-title":"Arq. Neuro-Psicjuiat. 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