{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,3,29]],"date-time":"2022-03-29T02:19:57Z","timestamp":1648520397853},"reference-count":16,"publisher":"FapUNIFESP (SciELO)","issue":"3B","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arq. Neuro-Psiquiatr."],"published-print":{"date-parts":[[1997,9]]},"abstract":"<jats:p>A toxina botul\u00ednica A \u00e9 a forma mais eficaz de tratar algumas distonias focais e o espasmo hemifacial. Devido a seu custo ainda elevado no nosso pa\u00eds, seu uso ainda n\u00e3o \u00e9 disseminado. Mostramos nossa experi\u00eancia com a toxina botul\u00ednica A em 115 pacientes, sendo 45 com espasmo hemifacial que apresentaram melhora acentuada ou total em 100%. Em 20 pacientes com blefaroespasmo essencial houve melhora acentuada ou total em 70% . Na s\u00edndrome de Meige, representada por 14 pacientes, a melhora acentuada ou total foi observada em 71,4%. Em 23 pacientes com distonia cervical observou-se melhora acentuada em 65,2%. Distonia da m\u00e3o, com 6 pacientes, apresentou o menor \u00edndice de melhora acentuada (2 pacientes, 33,3%). As complica\u00e7\u00f5es de car\u00e1ter transit\u00f3rio ocorreram, sendo as mais frequentes ptose palpebral e diminui\u00e7\u00e3o da for\u00e7a palpebral e a mais grave, pneumonia aspirativa. Acreditamos que a toxina \u00e9 forma eficaz e habitualmente segura de tratamento destas condi\u00e7\u00f5es cl\u00ednicas.<\/jats:p>","DOI":"10.1590\/s0004-282x1997000400006","type":"journal-article","created":{"date-parts":[[2010,10,17]],"date-time":"2010-10-17T01:13:42Z","timestamp":1287278022000},"page":"553-557","source":"Crossref","is-referenced-by-count":5,"title":["Experi\u00eancia com aplica\u00e7\u00e3o de toxina botul\u00ednica A em 115 pacientes"],"prefix":"10.1590","volume":"55","author":[{"given":"Luiz Augusto F.","family":"Andrade","sequence":"first","affiliation":[{"name":"Universidade Federal de S\u00e3o Paulo"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vanderci","family":"Borges","sequence":"additional","affiliation":[{"name":"Universidade Federal de S\u00e3o Paulo"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Henrique Ballalai","family":"Ferraz","sequence":"additional","affiliation":[{"name":"Universidade Federal de S\u00e3o 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