{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T12:50:12Z","timestamp":1777380612117,"version":"3.51.4"},"reference-count":30,"publisher":"FapUNIFESP (SciELO)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arq. Neuro-Psiquiatr."],"published-print":{"date-parts":[[1998,6]]},"abstract":"<jats:p>The authors assessed 116 cases of meningiomas classified as typical, atypical and anaplastic and they used an immunohistochemical technique for estrogen and progesterone receptors attempting to determine if there is any difference between typical and non-typical tumors in relation to hormone receptors. The immunohistochemical technique to estrogen receptors was negative in all meningiomas studied. Progesterone receptors were detected in 58.3% of typical, and in 48.2% of non-typical meningiomas. This difference was not statistically significant. However, individually considering the criteria used for selection of non-typical tumours, those that concurrently displayed brain invasion and increased mitotic activity or necrosis, as well as the summation of those three features, were predominantly negative for progesterone receptors (respectively p=0.038; p=0.001; and p=0.044). The authors conclude that estrogen receptors were not present in meningiomas; that progesterone receptors in isolation are not enough to predict a higher tumoral malignancy but can be useful associated with other histological features.<\/jats:p>","DOI":"10.1590\/s0004-282x1998000200005","type":"journal-article","created":{"date-parts":[[2005,4,15]],"date-time":"2005-04-15T14:22:13Z","timestamp":1113574933000},"page":"193-199","source":"Crossref","is-referenced-by-count":15,"title":["Meningiomas and hormonal receptors: immunohistochemical study in typical and non-typical tumors"],"prefix":"10.1590","volume":"56","author":[{"given":"ARLETE","family":"HILBIG","sequence":"first","affiliation":[{"name":"Funda\u00e7\u00e3o Faculdade Federal de Ci\u00eancias M\u00e9dicas de Porto Alegre"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L\u00cdGIA MARIA","family":"BARBOSA-COUTINHO","sequence":"additional","affiliation":[{"name":"Funda\u00e7\u00e3o Faculdade Federal de Ci\u00eancias M\u00e9dicas de Porto Alegre"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"530","reference":[{"key":"ref1","series-title":"Pathology of tumors of the nervous system","author":"Russell DS","year":"1989","edition":"5"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1136\/jnnp.21.2.89","article-title":"The relapsing course of certain meningiomas in relation to pregnancy and menstruation","volume":"21","author":"Bickerstaff ER","year":"1958","journal-title":"J Neurol Neurosurg Psychiatry","ISSN":"https:\/\/id.crossref.org\/issn\/0022-3050","issn-type":"print"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"1537","DOI":"10.1002\/1097-0142(19861001)58:7<1537::AID-CNCR2820580726>3.0.CO;2-P","article-title":"Association of breast cancer with meningioma","volume":"58","author":"Burns 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