{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,2]],"date-time":"2025-11-02T16:19:06Z","timestamp":1762100346121},"reference-count":15,"publisher":"FapUNIFESP (SciELO)","issue":"2A","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arq. Neuro-Psiquiatr."],"published-print":{"date-parts":[[2000,6]]},"abstract":"<jats:p>A transforma\u00e7\u00e3o de uma cefal\u00e9ia prim\u00e1ria em cefal\u00e9ia cr\u00f4nica di\u00e1ria (CCD) pode ou n\u00e3o estar relacionada com o abuso de analg\u00e9sicos, pois a influ\u00eancia desse abuso sobre os mecanismos fisiopatol\u00f3gicos permanecem inconclusivos. Descrevemos tr\u00eas pacientes (mulher, 65 e 39 anos e homem, 46 anos) com cefal\u00e9ia cervicog\u00eanica (CC) que abusavam de analg\u00e9sicos (derivados da ergotamina) e foram submetidos a infiltra\u00e7\u00e3o do nervo occipital maior (NOM). Ao final de tr\u00eas dias do tratamento, melhora total dos sintomas \u00e1lgicos foram registrados, o que permitiu retirada completa dos derivados da ergotamina. A CC n\u00e3o pode ser classificada dentro das cefal\u00e9ias cr\u00f4nica di\u00e1rias visto que apresenta uma etiologia org\u00e2nica; entretanto, se a dor for di\u00e1ria e o diagn\u00f3stico tardio, o uso indiscriminado e abusivo de analg\u00e9sicos pode ocorrer. Nos casos descritos o uso abusivo de analg\u00e9sicos n\u00e3o influenciou a evolu\u00e7\u00e3o natural desta cefal\u00e9ia ap\u00f3s o tratamento com a infiltra\u00e7\u00e3o do NOM, uma vez que todos os pacientes submetidos a infiltra\u00e7\u00e3o apresentaram melhora total de seus sintomas dolorosos sem cefal\u00e9ia rebote ou tampouco depend\u00eancia farmacol\u00f3gica. Esta \u00e9 uma evid\u00eancia que a CC apresenta uma etiol\u00f3gia org\u00e2nica, n\u00e3o sendo influenciada em sua fisiopatologia pelo uso abusivo de derivados da ergotamina.<\/jats:p>","DOI":"10.1590\/s0004-282x2000000200022","type":"journal-article","created":{"date-parts":[[2005,4,15]],"date-time":"2005-04-15T14:25:47Z","timestamp":1113575147000},"page":"336-341","source":"Crossref","is-referenced-by-count":2,"title":["O padr\u00e3o biol\u00f3gico da cefal\u00e9ia cervicog\u00eanica pode ser alterado pelo uso excessivo de ergotam\u00ednicos ou pela sua retirada?"],"prefix":"10.1590","volume":"58","author":[{"given":"ELCIO JULIATO","family":"PIOVESAN","sequence":"first","affiliation":[{"name":"Universidade Federal do Paran\u00e1 (UFPR)"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"PEDRO ANDR\u00c9","family":"KOWACS","sequence":"additional","affiliation":[{"name":"Universidade Federal do Paran\u00e1 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