{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,11]],"date-time":"2026-05-11T23:01:18Z","timestamp":1778540478628,"version":"3.51.4"},"reference-count":13,"publisher":"FapUNIFESP (SciELO)","issue":"2B","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arq. Neuro-Psiquiatr."],"published-print":{"date-parts":[[2003,6]]},"abstract":"<jats:p>INTRODU\u00c7\u00c3O: A s\u00edndrome de Hopkins (SH) \u00e9 caracterizada por monoplegia ou diplegia, decorrente de les\u00e3o no corno anterior da medula, que se segue a um ataque agudo de asma, ocorre geralmente em crian\u00e7as e sua etiologia ainda n\u00e3o est\u00e1 definida. H\u00e1 34 casos descritos no mundo, sendo este o primeiro relato na Am\u00e9rica do Sul e durante o primeiro ano de vida. CASO: Crian\u00e7a internada aos 4 meses de idade com quadro de sibil\u00e2ncia e insufici\u00eancia respirat\u00f3ria. Cerca de 3 dias ap\u00f3s melhora do quadro respirat\u00f3rio, observou-se perda de for\u00e7a nos membros inferiores. Teve alta hospitalar com regress\u00e3o do quadro respirat\u00f3rio mantendo a paraparesia. Reinternada aos 9 meses de idade por novo quadro de broncoespasmo, demonstrando paralisia fl\u00e1cida assim\u00e9trica (E&gt;D) e atrofia nos membros inferiores. EXAME NEUROL\u00d3GICO: for\u00e7a e reflexos miot\u00e1ticos normais nos membros superiores, arreflexia miot\u00e1tica nos membros inferiores e sensibilidade preservada. Exames de l\u00edquor, resson\u00e2ncia magn\u00e9tica de coluna lombossacra e potencial evocado somatossensitivo dos membros inferiores: normais. BI\u00d3PSIA MUSCULAR: Grupamento de fibras. A eletroneuromiografia demonstrou sinais de les\u00e3o do neur\u00f4nio motor do corno anterior da medula nos met\u00e2meros lombossacros. CONCLUS\u00c3O: A S\u00edndrome de Hopkins, apesar de rara, deve ser lembrada no diagn\u00f3stico diferencial de paralisias fl\u00e1cidas, quando houver concomit\u00e2ncia com asma.<\/jats:p>","DOI":"10.1590\/s0004-282x2003000300033","type":"journal-article","created":{"date-parts":[[2005,4,15]],"date-time":"2005-04-15T14:35:25Z","timestamp":1113575725000},"page":"494-498","source":"Crossref","is-referenced-by-count":2,"title":["S\u00edndrome de Hopkins no diagn\u00f3stico diferencial das paralisias fl\u00e1cidas na inf\u00e2ncia: aspectos cl\u00ednicos e neurofisiol\u00f3gicos. Relato de caso"],"prefix":"10.1590","volume":"61","author":[{"given":"Daniel B.","family":"Nora","sequence":"first","affiliation":[{"name":"Pontif\u00edcia Universidade Cat\u00f3lica do Rio Grande do Sul, Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Irenio","family":"Gomes","sequence":"additional","affiliation":[{"name":"Hospital M\u00e3e de Deus"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gibran","family":"El Ammar","sequence":"additional","affiliation":[{"name":"Pontif\u00edcia Universidade Cat\u00f3lica do Rio Grande do Sul, Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Magda L.","family":"Nunes","sequence":"additional","affiliation":[{"name":"Pontif\u00edcia Universidade Cat\u00f3lica do Rio Grande do Sul, Brasil; PUCRS"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"530","reference":[{"key":"ref1","first-page":"273","article-title":"A new syndrome: poliomyelitis-like illness associated with 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