{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T13:29:57Z","timestamp":1762003797445},"reference-count":25,"publisher":"FapUNIFESP (SciELO)","issue":"3B","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arq. Neuro-Psiquiatr."],"published-print":{"date-parts":[[2003,9]]},"abstract":"<jats:p>Apresentamos dois casos de histoplasmose em que o acometimento do sistema nervoso central foi a \u00fanica manifesta\u00e7\u00e3o cl\u00ednica da doen\u00e7a. Revis\u00e3o da literatura permitiu confirmar a raridade dessa forma de patologia, em particular em crian\u00e7as, sendo o segundo caso aqui apresentado o de mais baixa idade na literatura nacional. S\u00e3o feitos coment\u00e1rios sobre a variedade das apresenta\u00e7\u00f5es cl\u00ednicas e os principais diagn\u00f3sticos diferenciais da doen\u00e7a. S\u00e3o discutidos os resultados laboratoriais, tanto em rela\u00e7\u00e3o \u00e0s altera\u00e7\u00f5es liqu\u00f3ricas quanto aos resultados sorol\u00f3gicos. Finalmente, \u00e9 analisada a terap\u00eautica dessa forma de infec\u00e7\u00e3o f\u00fangica tanto em rela\u00e7\u00e3o aos medicamentos utiliz\u00e1veis quanto \u00e0 dura\u00e7\u00e3o prolongada aconselh\u00e1vel para o tratamento espec\u00edfico.<\/jats:p>","DOI":"10.1590\/s0004-282x2003000500029","type":"journal-article","created":{"date-parts":[[2005,4,15]],"date-time":"2005-04-15T14:35:56Z","timestamp":1113575756000},"page":"859-863","source":"Crossref","is-referenced-by-count":8,"title":["Histoplasmose do sistema nervoso central como \u00fanica manifesta\u00e7\u00e3o da doen\u00e7a em pacientes imunocompetentes: apresenta\u00e7\u00e3o de dois casos"],"prefix":"10.1590","volume":"61","author":[{"given":"Guido C.","family":"Levi","sequence":"first","affiliation":[{"name":"Hospital do Servidor P\u00fablico Estadual 'Francisco Morato de Oliveira', Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cristina M.","family":"Pozzi","sequence":"additional","affiliation":[{"name":"HSPE"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S\u00f4nia M. 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