{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T18:52:42Z","timestamp":1648839162791},"reference-count":22,"publisher":"FapUNIFESP (SciELO)","issue":"3a","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arq. Neuro-Psiquiatr."],"published-print":{"date-parts":[[2005,9]]},"abstract":"<jats:p>INTRODU\u00c7\u00c3O: A hipertens\u00e3o gestacional \u00e9 a maior causa de morte materna no pa\u00eds e pode cursar com encefalopatia hip\u00f3xico-isqu\u00eamica no concepto levando a subseq\u00fcentes manifesta\u00e7\u00f5es neurol\u00f3gicas. OBJETIVO: Correlacionar a hipertens\u00e3o gestacional com indicadores de risco para o desenvolvimento neuropsicomotor do lactente. M\u00c9TODO: Foram avaliados 30 rec\u00e9m-nascidos, filhos de m\u00e3es que apresentaram quadro de hipertens\u00e3o gestacional, de forma consecutiva e prospectiva. Foram considerados como indicadores de risco os seguintes fatores: pequeno para a idade gestacional; sofrimento fetal agudo; in\u00edcio da hipertens\u00e3o gestacional; rec\u00e9m-nascido a termo\/pr\u00e9-termo; \u00edndice de Apgar; presen\u00e7a de cianose central; necessidade de m\u00e1scara de O2; cor do l\u00edquido amni\u00f3tico. Este estudo cumpriu duas etapas. Na primeira, realizamos o exame neurol\u00f3gico entre as primeiras 48-72 horas de vida do neonato. Em uma segunda etapa, os pacientes foram submetidos a uma segunda avalia\u00e7\u00e3o neurocl\u00ednica entre os 7 e 15 meses de vida. RESULTADOS: Seis rec\u00e9m-nascidos avaliados apresentaram altera\u00e7\u00f5es ao exame neurol\u00f3gico nas primeiras 72 horas de vida. Dos indicadores analisados, apenas o \u00edndice de Apgar de risco se correlacionou com o exame neurol\u00f3gico neonatal alterado de forma estatisticamente significativa. Os demais indicadores n\u00e3o apresentaram correla\u00e7\u00e3o positiva. Todas as crian\u00e7as reavaliadas na segunda etapa demonstraram exame neurol\u00f3gico e desenvolvimento neuropsicomotor normais, n\u00e3o sendo poss\u00edvel qualquer correla\u00e7\u00e3o com os indicadores de risco. CONCLUS\u00c3O: Os nossos dados sugerem que a hipertens\u00e3o gestacional per se parece n\u00e3o ser suficiente para causar danos neurol\u00f3gicos importantes ao concepto.<\/jats:p>","DOI":"10.1590\/s0004-282x2005000400014","type":"journal-article","created":{"date-parts":[[2006,1,9]],"date-time":"2006-01-09T13:15:35Z","timestamp":1136812535000},"page":"632-636","source":"Crossref","is-referenced-by-count":3,"title":["Desenvolvimento neuropsicomotor de lactentes filhos de m\u00e3es que apresentaram hipertens\u00e3o arterial na gesta\u00e7\u00e3o"],"prefix":"10.1590","volume":"63","author":[{"given":"Briana R.","family":"Dias","sequence":"first","affiliation":[{"name":"Universidade Estadual de Campinas, Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana Maria S.G.","family":"Piovesana","sequence":"additional","affiliation":[{"name":"Universidade Estadual de Campinas, Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria Augusta","family":"Montenegro","sequence":"additional","affiliation":[{"name":"Universidade Estadual de Campinas, Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marilisa M.","family":"Guerreiro","sequence":"additional","affiliation":[{"name":"Universidade Estadual de Campinas, Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"530","reference":[{"key":"ref1","first-page":"598","article-title":"Doen\u00e7a hipertensiva espec\u00edfica da gesta\u00e7\u00e3o: pr\u00e9-ecl\u00e2mpsia e ecl\u00e2mpsia","volume":"22","author":"Resende J","year":"1995","journal-title":"Obstetr\u00edcia"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1136\/fn.85.3.F170","article-title":"The relation between pre-eclampsia at term and neonatal encephalopahty","volume":"85","author":"Impey L","year":"2001","journal-title":"Arch Dis Child","ISSN":"http:\/\/id.crossref.org\/issn\/0003-9888","issn-type":"print"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"617","DOI":"10.33588\/rn.3107.2000324","article-title":"Encefalopatia hip\u00f3xico-isqu\u00e9mica del reci\u00e9n nacido a t\u00e9rmino: recientes avances, marcadores de hipoxia y opciones terap\u00e9uticas","volume":"31","author":"Rufo MC","year":"2000","journal-title":"Rev Neurol","ISSN":"http:\/\/id.crossref.org\/issn\/0210-0010","issn-type":"print"},{"key":"ref4","series-title":"Neurologia infantil","first-page":"667","volume-title":"Encefalopatias hip\u00f3xico-isqu\u00eamicas e hemorragias intracranianas","author":"Marques-Dias MJ","year":"1999"},{"key":"ref5","series-title":"Neurologia infantil","first-page":"10","volume-title":"Exame neurol\u00f3gico do rec\u00e9m-nascido de termo","author":"Diament A","year":"1999"},{"key":"ref6","series-title":"Neurology of the newborn","first-page":"296","volume-title":"Hipoxic-isquemic encephalopathy: neuropathology and pathogenesis","author":"Volpe JJ","year":"2001","edition":"4"},{"key":"ref7","first-page":"571","article-title":"Acquired diseases of the nervous system","volume":"24","author":"Keeling JW","year":"1993","journal-title":"Fetal Neonatal Pathology"},{"key":"ref8","series-title":"Neurologia infantil","first-page":"22","volume-title":"Avalia\u00e7\u00e3o neurol\u00f3gica do rec\u00e9m-nascido prematuro","author":"Gherpelli JL","year":"1999"},{"key":"ref9","series-title":"Neurologia infantil","first-page":"33","volume-title":"Exame neurol\u00f3gico do lactente","author":"Diament A","year":"1999"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/S0022-3476(67)80070-2","article-title":"Denver developmental screening","volume":"71","author":"Frankenburg WK","year":"1967","journal-title":"J Ped"},{"key":"ref11","series-title":"Neurology of the newborn","first-page":"277","volume-title":"Hypoxic-ischemic encephalopathy: intrauterine assessment","author":"Volpe JJ","year":"2001"},{"key":"ref12","series-title":"Neurology of the newborn","first-page":"331","volume-title":"Hypoxic-ischemic encephalopathy: clinical aspects","author":"Volpe JJ","year":"2001","edition":"4"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/0378-3782(77)90029-9","article-title":"Hypertension during pregnancy, with and without specific hypotensive treatment: I. 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