{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,6]],"date-time":"2026-11-06T15:48:14Z","timestamp":1793980094263,"version":"4.8.0"},"reference-count":62,"publisher":"FapUNIFESP (SciELO)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arq. Neuro-Psiquiatr."],"published-print":{"date-parts":[[2008,12]]},"abstract":"<jats:p>Spontaneous cervical arterial dissection (SCAD) is a non-traumatic tear or disruption in the wall of the internal carotid arteries or the vertebral arteries. It accounts for about 25% of strokes in patients aged under 45 years. Awareness of its clinical features and advances in imaging over the last two decades have contributed to earlier identification of this condition. SCAD has become the commonest form of vascular lesion identified in the cervical carotid and vertebral arteries, second only to atherosclerosis. This review is an update on the epidemiology, vulnerable arterial segments, risk factors, clinical features, diagnosis, current treatment and prognosis of SCAD.<\/jats:p>","DOI":"10.1590\/s0004-282x2008000600036","type":"journal-article","created":{"date-parts":[[2008,12,18]],"date-time":"2008-12-18T15:49:53Z","timestamp":1229615393000},"page":"922-927","source":"Crossref","is-referenced-by-count":22,"title":["Spontaneous cervical artery dissection: an update on clinical and diagnostic aspects"],"prefix":"10.1590","volume":"66","author":[{"given":"Cynthia Resende","family":"Campos-Herrera","sequence":"first","affiliation":[{"name":"Municipal Hospital M\u00e1rio Gatti; University of S\u00e3o Paulo, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Milberto","family":"Scaff","sequence":"additional","affiliation":[{"name":"Hospital of Clinics"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F\u00e1bio Iuji","family":"Yamamoto","sequence":"additional","affiliation":[{"name":"Hospital of Clinics"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adriana Bastos","family":"Conforto","sequence":"additional","affiliation":[{"name":"Hospital of Clinics"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"530","reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1038\/ncpneuro0683","article-title":"Dissection of brain-supplying arteries","volume":"4","author":"Caplan LR","year":"2008","journal-title":"Nat Cli Pract Neurol"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"898","DOI":"10.1056\/NEJM200103223441206","article-title":"Spontaneous dissection of the carotid and vertebral arteries","volume":"344","author":"Schievink W","year":"2001","journal-title":"N Eng J Med","ISSN":"https:\/\/id.crossref.org\/issn\/0028-4793","issn-type":"print"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"2646","DOI":"10.1161\/01.STR.29.12.2646","article-title":"Stroke patterns of internal carotid artery dissection in 40 patients","volume":"29","author":"Lucas C","year":"1998","journal-title":"Stroke","ISSN":"https:\/\/id.crossref.org\/issn\/0039-2499","issn-type":"print"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1002\/ana.410190204","article-title":"Spontaneous dissection of the cervical internal carotid artery","volume":"19","author":"Mokri B","year":"1986","journal-title":"Ann Neurol","ISSN":"https:\/\/id.crossref.org\/issn\/0364-5134","issn-type":"print"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"1475","DOI":"10.1001\/archneur.55.11.1475","article-title":"Impaired clearance of emboli (washout) is an important link between hypoperfusion, embolism and ischemic stroke","volume":"55","author":"Caplan LR","year":"1998","journal-title":"Arch Neurol","ISSN":"https:\/\/id.crossref.org\/issn\/0003-9942","issn-type":"print"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1159\/000090791","article-title":"Is hypoperfusion an important cause of strokes? 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