{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,3,25]],"date-time":"2024-03-25T19:22:33Z","timestamp":1711394553484},"reference-count":32,"publisher":"FapUNIFESP (SciELO)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arq. Neuro-Psiquiatr."],"published-print":{"date-parts":[[2010,2]]},"abstract":"<jats:p>OBJECTIVE: To determine the relationship between Taenia antigen (TA) detection in cerebrospinal fluid (CSF) and magnetic resonance imaging (MRI) findings in patients with definite diagnosis of neurocysticercosis (NC). METHOD: Sixty-three patients with definite diagnosis of NC were submitted to a MRI of the brain, and to a CSF examination, with a meticulous search for TA by ELISA. RESULTS: TA detection was positive in 36 patients (57.1%). A total of 836 lesions were analyzed, greatly within the cerebral parenchyma (98.7 of the lesions). Intact or non-degenerating cysts were the most common evolutive phase observed (50.4% of all lesions), 22.1% were degenerating cysts and 19.5% calcified cysts. We observed a significant relationship between TA levels detected and the total number of lesions and the number of non-degenerating cysts, but not with calcified lesions. CONCLUSION: According to our results, we propose at least four important types of contribution: (1) TA detection may allow etiologic diagnosis in transitional phases of NC, with non-characteristic images; (2) in final stages of evolution of cysticercoids in the CNS, lesions may not appear on CT or MRI, and TA detection may contribute to a definite etiologic diagnosis; (3) TA detection may permit diagnosis of NC in some patients with previous negative tests for antibody detection in CSF; (4) TA detection may represent an accurate marker of disease activity in the epileptic form of NC.<\/jats:p>","DOI":"10.1590\/s0004-282x2010000100003","type":"journal-article","created":{"date-parts":[[2010,3,24]],"date-time":"2010-03-24T05:36:50Z","timestamp":1269409010000},"page":"07-11","source":"Crossref","is-referenced-by-count":9,"title":["Neurocysticercosis: relationship between Taenia antigen levels in CSF and MRI"],"prefix":"10.1590","volume":"68","author":[{"given":"Ronaldo","family":"Abraham","sequence":"first","affiliation":[{"name":"University of Taubat\u00e9,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jos\u00e9 Antonio","family":"Livramento","sequence":"additional","affiliation":[{"name":"S\u00e3o Paulo University Medical School,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cl\u00e1udia da Costa","family":"Leite","sequence":"additional","affiliation":[{"name":"FMUSP"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alessandra Xavier","family":"Pardini","sequence":"additional","affiliation":[{"name":"S\u00e3o Paulo University Biomedical Science Institute of,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adelaide Jos\u00e9","family":"Vaz","sequence":"additional","affiliation":[{"name":"S\u00e3o Paulo University Biomedical Science Institute of,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lu\u00eds dos Ramos","family":"Machado","sequence":"additional","affiliation":[{"name":"S\u00e3o Paulo University Medical School,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"530","reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1016\/S1473-3099(02)00454-1","article-title":"Neurocysticercosis: an update","volume":"2","author":"Carpio A","year":"2002","journal-title":"Lancet Infect Dis"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1055\/s-2005-917661","article-title":"Neurocysticercosis","volume":"25","author":"Del Brutto OH","year":"2005","journal-title":"Sem Neurol"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1016\/S1474-4422(05)70194-0","article-title":"Neurocysticercosis: updated concepts about an old disease","volume":"4","author":"Garcia HH","year":"2005","journal-title":"Lancet 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