{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,4,3]],"date-time":"2022-04-03T17:03:42Z","timestamp":1649005422248},"reference-count":18,"publisher":"FapUNIFESP (SciELO)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev. Sa\u00fade P\u00fablica"],"published-print":{"date-parts":[[1995,8]]},"abstract":"<jats:p>Estudou-se a rela\u00e7\u00e3o entre o desenvolvimento da hepatomegalia, da esplenomegalia, peso corporal e taxa de mortalidade em camundongos experimentalmente infectados por Schistosoma mansoni com o grau de susceptibilidade de Biomphalaria glahrata e B. tenagophila nas quais se desenvolveram as cerc\u00e1rias infectantes respectivamente, das linhagens BH e SJ. Foram utilizados como hospedeiro definitivo camundongos Swiss, SPF e como hospedeiros intermedi\u00e1rios popula\u00e7\u00f5es de moluscos selecionados geneticamente para o car\u00e1ter susceptibilidade. Foram observados menores pesos corporais e das visceras em camundongos infectados com cerc\u00e1rias provenientes de moluscos que apresentaram elevado grau de susceptibilidade. A maior susceptibilidade dos moluscos \u00e0 infec\u00e7\u00e3o pelo S. mansoni correspondeu a uma menor sobreviv\u00eancia dos camundongos infectados. Os resultados fazem crer que a maior adapta\u00e7\u00e3o do parasita ao hospedeiro intermedi\u00e1rio, traduzidos pelas taxas mais elevadas de susceptibilidade, pode levar a um comportamento diferente deste parasita no hospedeiro definitivo.<\/jats:p>","DOI":"10.1590\/s0034-89101995000400002","type":"journal-article","created":{"date-parts":[[2005,4,27]],"date-time":"2005-04-27T10:12:40Z","timestamp":1114596760000},"page":"265-270","source":"Crossref","is-referenced-by-count":10,"title":["Rela\u00e7\u00e3o entre a patogenicidade do Schistosoma mansoni em camundongos e a susceptibilidade do molusco vetor: III. Mortalidade, pesos corporal e das v\u00edsceras"],"prefix":"10.1590","volume":"29","author":[{"given":"Eliana Maria","family":"Zanotti-Magalh\u00e3es","sequence":"first","affiliation":[{"name":"Universidade Estadual de Campinas,  Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luiz Augusto","family":"Magalh\u00e3es","sequence":"additional","affiliation":[{"name":"Universidade Estadual de Campinas,  Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jos\u00e9 Ferreira de","family":"Carvalho","sequence":"additional","affiliation":[{"name":"Universidade Estadual de Campinas,  Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"530","reference":[{"key":"ref1","first-page":"249","article-title":"Aspectos experimentais da esplenomegalia da esquistossomose","volume":"4","author":"ANDRADE Z. A.","year":"1962","journal-title":"Rev. Inst. Med. 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