{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,13]],"date-time":"2026-11-13T21:41:23Z","timestamp":1794606083166,"version":"4.9.1"},"reference-count":7,"publisher":"FapUNIFESP (SciELO)","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev. Sa\u00fade P\u00fablica"],"published-print":{"date-parts":[[1998,10]]},"abstract":"<jats:p>OBJETIVO: Seguindo-se \u00e0 epidemia de dengue (DEN), em 1994, em Fortaleza, Cear\u00e1, causada pelo sorotipo 2 (DEN-2), realizou-se inqu\u00e9rito soro-epidemiol\u00f3gico aleat\u00f3rio para avaliar e dimensionar o impacto da mesma e a preval\u00eancia do dengue por distrito sanit\u00e1rio. M\u00c9TODO: Foi aplicado question\u00e1rio contendo informa\u00e7\u00f5es gerais, condi\u00e7\u00f5es socio-econ\u00f4micas, informa\u00e7\u00f5es sobre o quadro cl\u00ednico e tempo de doen\u00e7a. A amostra foi calculada para estimar uma preval\u00eancia de 20%, com erro relativo de 10%, e intervalo de confian\u00e7a de 95% (erro a de 5%). O sorteio e as an\u00e1lises foram realizadas por meio de computador usando programas apropriados. RESULTADOS E CONCLUS\u00d5ES: Foram colhidas 1.341 amostras de soro de 9 distritos sanit\u00e1rios, testadas por inibi\u00e7\u00e3o da hemaglutina\u00e7\u00e3o, sendo classificadas como negativas e positivas (respostas prim\u00e1ria - RP e secund\u00e1ria - RS). Foram reativas 588 (44%) amostras, sendo 93 (7%) RP e 495 (37%) RS. A preval\u00eancia global em Fortaleza variou de 21% a 71%. Houve 41% (243\/588) de infec\u00e7\u00f5es assintom\u00e1ticas (IA) e 59% (346\/588) sintom\u00e1ticas (IS). N\u00e3o houve diferen\u00e7a da preval\u00eancia quanto ao sexo, faixa et\u00e1ria e escolaridade, ao contr\u00e1rio da condi\u00e7\u00e3o socioecon\u00f4mica que apresentou diferen\u00e7as estatisticamente significantes (p &lt; 0,001). Ocorreram mais IA (p&lt;0,001) e IS (p&lt;0,0001) em casos de RS que RP, com signific\u00e2ncia estat\u00edstica em ambos os sexos. Os sintomas mais prevalentes no casos confirmados foram febre, cefal\u00e9ia, mialgias, exantema, mal estar geral, tontura e artralgias, sendo que prurido, dor ocular, exantema e gengivorragia foram estatisticamente significantes (p&lt;0,005). Tontura e artralgias foram mais associados com RS que com RP, havendo diferen\u00e7as estat\u00edsticas (p &lt;0,05).<\/jats:p>","DOI":"10.1590\/s0034-89101998000500007","type":"journal-article","created":{"date-parts":[[2005,4,27]],"date-time":"2005-04-27T10:16:12Z","timestamp":1114596972000},"page":"447-454","source":"Crossref","is-referenced-by-count":54,"title":["Epidemia de dengue em Fortaleza, Cear\u00e1: inqu\u00e9rito soro-epidemiol\u00f3gico aleat\u00f3rio"],"prefix":"10.1590","volume":"32","author":[{"given":"Pedro F. C.","family":"Vasconcelos","sequence":"first","affiliation":[{"name":"Instituto Evandro Chagas,  Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9 Wellington O.","family":"Lima","sequence":"additional","affiliation":[{"name":"Funda\u00e7\u00e3o Nacional de Sa\u00fade,  Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Am\u00e9lia P. A. Travassos da","family":"Rosa","sequence":"additional","affiliation":[{"name":"Instituto Evandro Chagas,  Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria J.","family":"Timb\u00f3","sequence":"additional","affiliation":[{"name":"Funda\u00e7\u00e3o Nacional de Sa\u00fade,  Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elizabeth S. Travassos da","family":"Rosa","sequence":"additional","affiliation":[{"name":"Instituto Evandro Chagas,  Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hascalon R.","family":"Lima","sequence":"additional","affiliation":[{"name":"Funda\u00e7\u00e3o Nacional de Sa\u00fade,  Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sueli G.","family":"Rodrigues","sequence":"additional","affiliation":[{"name":"Instituto Evandro Chagas,  Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jorge F. S. Travassos da","family":"Rosa","sequence":"additional","affiliation":[{"name":"Instituto Evandro Chagas,  Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"530","reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"1204","DOI":"10.1093\/oxfordjournals.aje.a117579","article-title":"Symptoms of dengue fever in relation to host immunologic response and virus serotype, Puerto Rico, 1990-1991","volume":"142","author":"COBRA C.","year":"1995","journal-title":"Am. J. Epidemiol.","ISSN":"https:\/\/id.crossref.org\/issn\/0002-9262","issn-type":"print"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1093\/oxfordjournals.epirev.a036196","article-title":"Review of the factors modulating dengue transmission","volume":"17","author":"KUNO G.","year":"1995","journal-title":"Epidemiol. Rev."},{"key":"ref3","series-title":"Plano Diretor de Erradica\u00e7\u00e3o do Aedes aegypti do Brasil","year":"1996"},{"key":"ref4","series-title":"Dengue and dengue hemorrhagic fever in the Americas: guidelines for prevention and control","volume":"548","year":"1994"},{"key":"ref5","first-page":"167","article-title":"The use of a microhemagglutination-inhibition test to follow antibody response after arthropod-borne virus infection in a community of forest animals","volume":"11 (Parte A)","author":"SHOPE R.E.","year":"1963","journal-title":"An. Microbiol."},{"key":"ref6","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1590\/S0036-46651995000300012","article-title":"A large epidemic of dengue fever with dengue hemorrhagic cases in Cear\u00e1 State, Brazil, 1994","volume":"37","author":"VASCONCELOS P.F.C.","year":"1995","journal-title":"Rev. Inst. Med. Trop S. Paulo"},{"key":"ref7","series-title":"Dengue haemorrhagic fever: diagnosis, treatment and control","year":"1996"}],"container-title":["Revista de Sa\u00fade P\u00fablica"],"original-title":[],"link":[{"URL":"http:\/\/www.scielo.br\/pdf\/rsp\/v32n5\/32n5a4.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,5,24]],"date-time":"2017-05-24T16:44:10Z","timestamp":1495644250000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.scielo.br\/scielo.php?script=sci_arttext&pid=S0034-89101998000500007&lng=pt&tlng=pt"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1998,10]]},"references-count":7,"journal-issue":{"issue":"5","published-print":{"date-parts":[[1998,10]]}},"alternative-id":["S0034-89101998000500007"],"URL":"https:\/\/doi.org\/10.1590\/s0034-89101998000500007","relation":{},"ISSN":["0034-8910"],"issn-type":[{"value":"0034-8910","type":"electronic"}],"subject":[],"published":{"date-parts":[[1998,10]]}}}