{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T14:03:01Z","timestamp":1761487381402},"reference-count":17,"publisher":"FapUNIFESP (SciELO)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev. Sa\u00fade P\u00fablica"],"published-print":{"date-parts":[[2003,4]]},"abstract":"<jats:p>OBJETIVO: Validar a utiliza\u00e7\u00e3o da cicatriz vacinal de BCG como um indicador de vacina\u00e7\u00e3o. M\u00c9TODOS: Foi realizado um estudo transversal em 52.348 escolares, entre 6 e 14 anos de idade, que possu\u00edam exame de cicatriz vacinal do BCG e que participaram de um ensaio cl\u00ednico randomizado e controlado na cidade de Manaus, Brasil. Os dados da leitura da cicatriz vacinal foram comparados com a informa\u00e7\u00e3o sobre a vacina\u00e7\u00e3o passada fornecida pelos cart\u00f5es vacinais ou informa\u00e7\u00e3o dos respons\u00e1veis. Em uma subamostra foi realizada leitura dupla com c\u00e1lculo do coeficiente Kappa. Para an\u00e1lise dos dados utilizou-se o Stata 7. RESULTADOS: Do total de 52.348 escolares estudados, 29.254 possu\u00edam informa\u00e7\u00e3o sobre cicatriz vacinal coletada por meio de carta aos pais, e 4.947 possu\u00edam hist\u00f3ria de vacina\u00e7\u00e3o coletada pelo cart\u00e3o de vacinas. Observou-se elevada concord\u00e2ncia entre a dupla leitura de cicatriz vacinal (Kappa =0,81). A sensibilidade da leitura de cicatriz vacinal foi 96,6% (95% IC 96,0-97,1) e a especificidade foi 71,1% (95% IC 55,7-83,7) quando o padr\u00e3o ouro utilizado foi a concord\u00e2ncia entre a carta aos pais e a informa\u00e7\u00e3o do cart\u00e3o de vacinas. A sensibilidade foi de 96,1%, 97,3% e 95,3% para crian\u00e7as vacinadas at\u00e9 um m\u00eas de idade, at\u00e9 4 meses e at\u00e9 um ano de idade, respectivamente. CONCLUS\u00d5ES: Os valores encontrados para sensibilidade e especificidade foram independentes da idade da realiza\u00e7\u00e3o da leitura de cicatriz vacinal. O exame da cicatriz vacinal mostrou ser um bom indicador para avaliar a situa\u00e7\u00e3o vacinal referente ao BCG.<\/jats:p>","DOI":"10.1590\/s0034-89102003000200015","type":"journal-article","created":{"date-parts":[[2005,4,27]],"date-time":"2005-04-27T10:25:39Z","timestamp":1114597539000},"page":"254-259","source":"Crossref","is-referenced-by-count":8,"title":["Sensibilidade e especificidade da leitura da cicatriz vacinal do BCG"],"prefix":"10.1590","volume":"37","author":[{"given":"Susan M","family":"Pereira","sequence":"first","affiliation":[{"name":"Universidade Federal da Bahia,  Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana L","family":"Bierrenbach","sequence":"additional","affiliation":[{"name":"London University,  UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"In\u00eas","family":"Dourado","sequence":"additional","affiliation":[{"name":"Universidade Federal da Bahia,  Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maur\u00edcio L","family":"Barreto","sequence":"additional","affiliation":[{"name":"Universidade Federal da Bahia,  Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria Yury","family":"Ichihara","sequence":"additional","affiliation":[{"name":"Universidade Federal da Bahia,  Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Miguel A","family":"Hijjar","sequence":"additional","affiliation":[{"name":"Funda\u00e7\u00e3o Nacional de Sa\u00fade,  Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L C","family":"Rodrigues","sequence":"additional","affiliation":[{"name":"London University,  UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"530","reference":[{"key":"ref1","first-page":"1","article-title":"Tuberculosis prevention trial, Madras","volume":"72","author":"Baily GV","year":"1980","journal-title":"Indian J Med 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