{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,4,3]],"date-time":"2022-04-03T15:20:33Z","timestamp":1648999233260},"reference-count":45,"publisher":"FapUNIFESP (SciELO)","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev. Sa\u00fade P\u00fablica"],"published-print":{"date-parts":[[2003,10]]},"abstract":"<jats:p>Desde os primeiros anos da epidemia de Aids, grandes diferen\u00e7as geogr\u00e1ficas na preval\u00eancia de infec\u00e7\u00e3o pelo HIV foram registradas entre pa\u00edses vizinhos e regi\u00f5es vizinhas dentro de um mesmo pa\u00eds na \u00c1frica subsaariana. Tais diferen\u00e7as n\u00e3o podiam ser completamente explicadas por fatores como o comportamento sexual e o uso de preservativos. Um ac\u00famulo de dados epidemiol\u00f3gicos vem mostrando que a circuncis\u00e3o masculina desempenha um efeito protetor contra a aquisi\u00e7\u00e3o heterossexual do HIV pelo homem na \u00c1frica subsaariana e provavelmente contribui para as acentuadas diferen\u00e7as de preval\u00eancia de HIV. Assim, realizou-se uma atualiza\u00e7\u00e3o dos estudos conduzidos em solo africano sobre a associa\u00e7\u00e3o entre circuncis\u00e3o masculina e infec\u00e7\u00e3o pelo HIV, as origens da pr\u00e1tica da circuncis\u00e3o entre as popula\u00e7\u00f5es humanas, os mecanismos pelos quais a presen\u00e7a do prep\u00facio aumentaria a susceptibilidade de aquisi\u00e7\u00e3o heterossexual do HIV pelo homem, sua associa\u00e7\u00e3o com outras doen\u00e7as infecciosas e tamb\u00e9m neopl\u00e1sicas, o debate sobre a conveni\u00eancia da ado\u00e7\u00e3o de pr\u00e1ticas de circuncis\u00e3o como estrat\u00e9gia de controle da epidemia de HIV na \u00c1frica, a escassa literatura brasileira sobre circuncis\u00e3o masculina e as perspectivas de investiga\u00e7\u00f5es futuras.<\/jats:p>","DOI":"10.1590\/s0034-89102003000500022","type":"journal-article","created":{"date-parts":[[2005,4,27]],"date-time":"2005-04-27T14:26:16Z","timestamp":1114611976000},"page":"678-686","source":"Crossref","is-referenced-by-count":3,"title":["A circuncis\u00e3o masculina e a transmiss\u00e3o heterossexual do HIV"],"prefix":"10.1590","volume":"37","author":[{"given":"Walter A","family":"Eyer-Silva","sequence":"first","affiliation":[{"name":"Universidade do Rio de Janeiro,  Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"530","reference":[{"key":"ref1","series-title":"Pathology","volume-title":"Geographic pathology","author":"Anderson WAD","year":"1977","edition":"7"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"S15","DOI":"10.1097\/00002030-200108004-00003","article-title":"Ecological and individual level analysis of risk factors for HIV infection in four urban populations in sub-Saharan Africa with different levels of HIV 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