{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T07:26:21Z","timestamp":1761895581299},"reference-count":19,"publisher":"FapUNIFESP (SciELO)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev. Inst. Med. trop. S. Paulo"],"published-print":{"date-parts":[[1985,6]]},"abstract":"<jats:p>Foram cultivadas fezes de 620 indiv\u00edduos para a pesquisa de amebas de vida livre, sendo 514 pacientes do Hospital Universit\u00e1rio Pedro Ernesto (UERJ) e 106 crian\u00e7as e adultos de um orfanato. Foram positivas 70 amostras (11,2%) sendo 55 provenientes de pacientes do HU-UERJ e 15 de internos do orfanato. Foram isoladas 60 amostras de Acanthamoeba, 6 de Vahlkampfia, 5 de Hartmannella e 1 Echinamoeba. Alguns indiv\u00edduos tiveram cultura de fezes repetidamente positiva para Acanthamoeba durante dois meses de observa\u00e7\u00e3o. Das amostras de Acanthamoeba isoladas, 28 foram inoculadas em camundongos por via intranasal, tendo sido reisoladas 16 (57,1%) amostras \u00e0 partir de c\u00e9rebro e (ou) pulm\u00f5es dos animais. O estudo histopatol\u00f3gico demonstrou processo inflamat\u00f3rio agudo com presen\u00e7a de polimorfonucleares e amebas no c\u00e9rebro e pulm\u00f5es de alguns animais. O encontro de amostras patog\u00eanicas em fezes humanas refor\u00e7a a hip\u00f3tese do eventual desenvolvimento, em indiv\u00edduos portadores, de meningoencefalite amebiana granulomatosa, como infec\u00e7\u00e3o oportun\u00edstica de origem end\u00f3gena.<\/jats:p>","DOI":"10.1590\/s0036-46651985000300007","type":"journal-article","created":{"date-parts":[[2012,10,27]],"date-time":"2012-10-27T09:57:30Z","timestamp":1351331850000},"page":"150-156","source":"Crossref","is-referenced-by-count":12,"title":["Amebas de vida livre no intestino humano: evid\u00eancias de parasitismo"],"prefix":"10.1590","volume":"27","author":[{"given":"H\u00e9rcules de","family":"Moura","sequence":"first","affiliation":[{"name":"UERJ"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Homero Coutinho","family":"Salazar","sequence":"additional","affiliation":[{"name":"UERJ"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Octavio","family":"Fernandes","sequence":"additional","affiliation":[{"name":"UERJ"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Denise Costa","family":"Lisboa","sequence":"additional","affiliation":[{"name":"UERJ"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francisca Gon\u00e7alves de","family":"Carvalho","sequence":"additional","affiliation":[{"name":"Hospital dos Servidores do Estado (INAMPS); IASERJ"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"530","reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"1473","DOI":"10.1056\/NEJM196606302742605","article-title":"Primary amoebic meningoencephalitis","volume":"274","author":"BUTT C. 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