{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T12:55:55Z","timestamp":1761742555281},"reference-count":24,"publisher":"FapUNIFESP (SciELO)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev. Inst. Med. trop. S. Paulo"],"published-print":{"date-parts":[[1997,7]]},"abstract":"<jats:p>Given that chagasic patients in the indeterminate form of this disease, can have abnormal motility of the digestive tract and immunologic abnormalities, we decided to assess the frequency of peptic disease and Helicobacter pylori (Hp) infection in these individuals. Twenty-one individuals, 13 males and 8 females, mean age 37.6 \u00b1 11.1 years, were examined. Biopsies of the duodenum, antrum, lesser and greater gastric curvature and esophagus were performed. The endoscopic findings were of chronic gastritis in 20 (95.2%) patients, duodenal ulcer in 3 (14.3%), gastric and duodenal ulcer in 3 (14.3%), gastric ulcer alone in 1 (4.8%), esophagitis in 5 (23.8%), and duodenitis in 5 (23.8%). The diagnosis of infection by the Hp was done by the urease test and histologic examination. Hp infection was found in 20 (95.2%) individuals: in 20 out of them in the antrum, in 17 in the lesser curvature, and in 17 in the greater curvature. Hp was not found in the esophagus and duodenum. The only individual with no evidence of infection by Hp was also the only one with normal endoscopic and histologic examinations. The histologic examinations confirmed the diagnoses of gastric ulcer as peptic, chronic gastritis in 20 patients, duodenitis in 14, and esophagitis in 9. In this series the patients had a high frequency of peptic disease, which was closely associated with Hp infection<\/jats:p>","DOI":"10.1590\/s0036-46651997000400005","type":"journal-article","created":{"date-parts":[[2005,4,27]],"date-time":"2005-04-27T09:24:27Z","timestamp":1114593867000},"page":"209-212","source":"Crossref","is-referenced-by-count":7,"title":["Peptic disease and Helicobacter pylori are highly prevalent in patients with the indeterminate form of chagas\u2019 disease: report of 21 cases"],"prefix":"10.1590","volume":"39","author":[{"given":"Luiz Carlos Marques de","family":"OLIVEIRA","sequence":"first","affiliation":[{"name":"Servi\u00e7o de Gastroenterologia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abadia Gilda","family":"BUSO","sequence":"additional","affiliation":[{"name":"Servi\u00e7o de Gastroenterologia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luiz","family":"SIQUEIRA FILHO","sequence":"additional","affiliation":[{"name":"Servi\u00e7o de Gastroenterologia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fl\u00e1via","family":"MORAES","sequence":"additional","affiliation":[{"name":"Servi\u00e7o de Gastroenterologia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Humberto Alves","family":"OLIVEIRA","sequence":"additional","affiliation":[{"name":"Servi\u00e7o de Gastroenterologia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roseli Maria","family":"OLIVEIRA","sequence":"additional","affiliation":[{"name":"Servi\u00e7o de Gastroenterologia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eliana Chaves","family":"SALOM\u00c3O","sequence":"additional","affiliation":[{"name":"Universidade Federal de Uberl\u00e2ncia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"530","reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1590\/S0036-46651993000200002","article-title":"Chronic gastritis and Helicobater pylori in digestive form of Chagas\u2019 disease","volume":"35","author":"BARBOSA A.J.A.","year":"1993","journal-title":"Rev. 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