{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,7,7]],"date-time":"2024-07-07T18:31:01Z","timestamp":1720377061465},"reference-count":23,"publisher":"FapUNIFESP (SciELO)","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev. Inst. Med. trop. S. Paulo"],"published-print":{"date-parts":[[1997,9]]},"abstract":"<jats:p>Coccidioidomycosis is an endemic infection with a relatively limited geographic distribution: Mexico, Guatemala, Honduras, Colombia, Venezuela, Bolivia, Paraguai, Argentina and the southwest of the United States. In these countries, the endemic area is restricted to the semiarid desert like regions which are similar to the northeast of Brazil. Case report: The patient is a 32 year-old male, born in the state of Bahia (Northeast of Brazil) and has been living in S\u00e3o Paulo (Southeast) for 6 years. He was admitted at Hospital das Cl\u00ednicas, at the Department of Pneumology in October 1996, with a 6 month history of progressive and productive cough, fever, malaise, chills, loss of weight, weakness and arthralgia in the small joints. Chest x-rays and computerized tomography disclosed an interstitial reticulonodular infiltrate with a cavity in the right upper lobe. The standard potassium hydroxide preparation of sputum and broncoalveolar lavage demonstrated the characteristic thickened wall spherules in various stages of development. Sabouraud dextrose agar, at 25\u00b0 C and 30\u00b0 C showed growth of white and cottony aerial micelium. The microscopic morphology disclosed branched hyphae characterized by thick walled, barrel shaped arthroconidia alternated with empty cells. The sorological studies with positive double immunodiffusion test, and also positive complement fixation test in 1\/128 dilution confirmed the diagnosis. The patient has been treated with ketoconazole and presents a favorable clinical and radiological evolution<\/jats:p>","DOI":"10.1590\/s0036-46651997000500010","type":"journal-article","created":{"date-parts":[[2005,5,9]],"date-time":"2005-05-09T18:14:05Z","timestamp":1115662445000},"page":"299-304","source":"Crossref","is-referenced-by-count":8,"title":["Coccidioidomycosis in Brazil. A case report"],"prefix":"10.1590","volume":"39","author":[{"given":"Marilena dos Anjos","family":"MARTINS","sequence":"first","affiliation":[{"name":"USP"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Evangelina da Motta Pacheco Alves de","family":"ARA\u00daJO","sequence":"additional","affiliation":[{"name":"USP"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marcelo Hisato","family":"KUWAKINO","sequence":"additional","affiliation":[{"name":"FMUSP"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elisabeth Maria","family":"HEINS-VACCARI","sequence":"additional","affiliation":[{"name":"HCFMUSP"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gilda Maria B\u00e1rbaro","family":"DEL NEGRO","sequence":"additional","affiliation":[{"name":"HCFMUSP"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jo\u00e3o Antonio","family":"VOZZA J\u00daNIOR","sequence":"additional","affiliation":[{"name":"FMUSP"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carlos da Silva","family":"LACAZ","sequence":"additional","affiliation":[{"name":"HCFMUSP"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"530","reference":[{"key":"ref1","first-page":"91","article-title":"Estudo comparativo do Granuloma coccidi\u00f3idico nos Estados Unidos e no Brasil","volume":"4","author":"ALMEIDA F. 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Otorrinolaring."},{"key":"ref10","first-page":"11","article-title":"Blastomicose Sul-Americana. Rea\u00e7\u00f5es Intrad\u00e9rmicas com a Paracoccidioidina, Coccidioidina e Blastomicetina","volume":"3","author":"LACAZ C. da S.","year":"1948","journal-title":"Rev. Hosp. Cl\u00edn. Fac. Med. S. Paulo","ISSN":"http:\/\/id.crossref.org\/issn\/0041-8781","issn-type":"print"},{"key":"ref11","first-page":"108","article-title":"Ensaios preliminares com a prova da coccidioidina em nosso meio","volume":"15","author":"LACAZ C. da S.","year":"1960","journal-title":"Rev. do Hosp. Cl\u00edn. Fac. Med. S. Paulo"},{"key":"ref12","first-page":"403","article-title":"Inqu\u00e9rito imunol\u00f3gico com esferulina em um hospital geral de S\u00e3o Paulo","volume":"24","author":"LACAZ C. da S.","year":"1978","journal-title":"Rev. Ass. m\u00e9d. bras."},{"key":"ref13","author":"MARTINS C. A. de S.","year":"1997"},{"key":"ref14","article-title":"Micosis lar\u00edngea con par\u00e1sitos an\u00e1logos a los megalospor\u00eddeos de Posadas","volume":"3","author":"MAZZA S.","year":"1927","journal-title":"Bol. Inst. Cl\u00edn. quir."},{"key":"ref15","first-page":"37","article-title":"Le nord-est Br\u00e9silien, r\u00e9gion d\u2019end\u00e9mie de Coccidioidomycose?: A propos d\u2019une micro-epid\u00e9mi\u00e9","volume":"7","author":"SIDRIN J. J. C.","year":"1997","journal-title":"J. Micol. m\u00e9d."},{"key":"ref16","first-page":"49","article-title":"Coccidioidomicose pulmonar aguda: Primeiro surto epid\u00eamico descrito no Cear\u00e1, segundo do Brasil","volume":"72","author":"SILVA L. C. L. da","year":"1997","journal-title":"J. bras. Med."},{"key":"ref17","first-page":"211","article-title":"Blastomicose sul-americana: Teste cut\u00e2neo com coccidioidin","volume":"6","author":"VERSIANI O.","year":"1946","journal-title":"Rev. bras. 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