{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T20:54:02Z","timestamp":1790283242874,"version":"4.1.0"},"reference-count":16,"publisher":"FapUNIFESP (SciELO)","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev. Inst. Med. trop. S. Paulo"],"published-print":{"date-parts":[[2002,10]]},"abstract":"<jats:p>Cranial CT scans of eleven immunocompetent children with central nervous system (CNS) infection due to Cryptococcus neoformans var. gattii were retrospectively reviewed. These children had an average age of 8.8 years and positive culture for C. n. var. gattii in cerebrospinal fluid. The most common signs and symptoms were headache, fever, nuchal rigidity, nausea and vomiting. No normal cranial CT was detected in any patient. Hypodense nodules were observed in all patients . The remaining scan abnormalities were as follows: nine had diffuse atrophy, six had hydrocephalus, and five had hydrocephalus coexistent with diffuse atrophy.<\/jats:p>","DOI":"10.1590\/s0036-46652002000500010","type":"journal-article","created":{"date-parts":[[2005,4,27]],"date-time":"2005-04-27T13:30:20Z","timestamp":1114608620000},"page":"283-287","source":"Crossref","is-referenced-by-count":22,"title":["The spectrum of computerized tomography (CT) findings in central nervous system (CNS) infection due to Cryptococcus neoformans var. gattii in immunocompetent children"],"prefix":"10.1590","volume":"44","author":[{"given":"Maria do Perp\u00e9tuo Socorro Costa","family":"CORR\u00caA","sequence":"first","affiliation":[{"name":"Universidade Federal do Par\u00e1, Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luiz Carlos","family":"SEVERO","sequence":"additional","affiliation":[{"name":"Universidade Federal do Rio Grande do Sul, Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fl\u00e1vio de Mattos","family":"OLIVEIRA","sequence":"additional","affiliation":[{"name":"Santa Casa, Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Klaus","family":"IRION","sequence":"additional","affiliation":[{"name":"Santa Casa, Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alberto Thomaz","family":"LONDERO","sequence":"additional","affiliation":[{"name":"Universidade Federal de Santa Maria, Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"530","reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1086\/515130","article-title":"Cryptococcosis in children with AIDS","volume":"28","author":"ABADI J.","year":"1999","journal-title":"Clin. infect. Dis.","ISSN":"https:\/\/id.crossref.org\/issn\/1058-4838","issn-type":"print"},{"key":"ref2","series-title":"Cryptococcus neoformans","author":"CASADEVAL A.","year":"1998"},{"key":"ref3","series-title":"Criptococose e seu agente etiol\u00f3gico no meio norte, Estados do Piau\u00ed e Maranh\u00e3o, Brasil","author":"CAVALCANTI M.A.S.","year":"1997"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1086\/313992","article-title":"Epidemiology and host- and variety-dependent characteristics of infection due to Cryptococcus neoformans in Australia and New Zealand. Australian Cryptococcal Study Group","volume":"31","author":"CHEN S.","year":"2000","journal-title":"Clin. infect. Dis.","ISSN":"https:\/\/id.crossref.org\/issn\/1058-4838","issn-type":"print"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1590\/S0037-86821999000500006","article-title":"Criptococose em crian\u00e7as no Estado do Par\u00e1, Brasil","volume":"32","author":"CORR\u00caA M.P.S.","year":"1999","journal-title":"Rev. Soc. bras. Med. trop.","ISSN":"https:\/\/id.crossref.org\/issn\/0037-8682","issn-type":"print"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"382","DOI":"10.7326\/0003-4819-94-3-382","article-title":"Cryptococcal intracerebral mass lesions: The role of computed tomography and nonsurgical management","volume":"94","author":"FUJITA N.K.","year":"1981","journal-title":"Ann. intern. Med.","ISSN":"https:\/\/id.crossref.org\/issn\/0003-4819","issn-type":"print"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1128\/JCM.15.3.535-537.1982","article-title":"Improved diagnostic medium for separation of Cryptococcus neoformans var. neoformans (serotypes A and D) and Cryptococcus neoformans var. gattii (serotypes B and C)","volume":"15","author":"KWON-CHUNG K.J.","year":"1982","journal-title":"J. clin. Microbiol.","ISSN":"https:\/\/id.crossref.org\/issn\/0095-1137","issn-type":"print"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"976","DOI":"10.1016\/0002-9343(59)90181-0","article-title":"Cryptococcosis (Torulosis): Current concepts and therapy","volume":"27","author":"LITTMAN M.L.","year":"1959","journal-title":"Amer. J. Med."},{"key":"ref9","doi-asserted-by":"crossref","first-page":"842","DOI":"10.1016\/S0009-9260(96)80080-8","article-title":"The spectrum of MRI findings in CNS cryptococcosis in AIDS","volume":"51","author":"MISZKIEL K.A.","year":"1996","journal-title":"Clin. Radiol."},{"key":"ref10","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1093\/clinids\/20.3.611","article-title":"Cryptococcal diasease of the CNS in immunocompetent hosts: influence of cryptococcal variety on clinical manifestations and outcome","volume":"20","author":"MITCHELL D.H.","year":"1995","journal-title":"Clin. infect. Dis.","ISSN":"https:\/\/id.crossref.org\/issn\/1058-4838","issn-type":"print"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"603","DOI":"10.2214\/ajr.154.3.2106227","article-title":"CT of intracranial cryptococcosis","volume":"154","author":"POPOVICH M.J.","year":"1990","journal-title":"Amer. J. Roentgenol."},{"key":"ref12","first-page":"15","article-title":"Relato de cinco casos de meningite criptoc\u00f3cica em crian\u00e7as com s\u00edndrome da imunodefici\u00eancia adquirida (AIDS)","volume":"4","author":"PY E.A.","year":"1997","journal-title":"Arq. bras. Pediat."},{"key":"ref13","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1093\/clinids\/18.3.369","article-title":"Clinical epidemiological study of 171 cases of cryptococcosis","volume":"18","author":"ROZENBAUM R.","year":"1994","journal-title":"Clin. infect. Dis.","ISSN":"https:\/\/id.crossref.org\/issn\/1058-4838","issn-type":"print"},{"key":"ref14","first-page":"183","article-title":"Criptococose: Apresenta\u00e7\u00e3o de um caso cl\u00ednico em crian\u00e7a de baixa idade","volume":"53","author":"SANTOS A.","year":"1982","journal-title":"J. Pediat."},{"key":"ref15","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1093\/clinids\/21.1.28","article-title":"Clinical and host differences between infections with the two varieties of Cryptococcus neoformans","volume":"21","author":"SPEED B.","year":"1995","journal-title":"Clin. infect. Dis.","ISSN":"https:\/\/id.crossref.org\/issn\/1058-4838","issn-type":"print"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"536","DOI":"10.1097\/00006454-199705000-00024","article-title":"Rarity of cryptococcal infection in children","volume":"16","author":"SPEED B.R.","year":"1997","journal-title":"Pediat. infect. Dis. J."}],"container-title":["Revista do Instituto de Medicina Tropical de S\u00e3o Paulo"],"original-title":[],"link":[{"URL":"http:\/\/www.scielo.br\/pdf\/rimtsp\/v44n5\/a10v44n5.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,4,7]],"date-time":"2020-04-07T02:49:53Z","timestamp":1586227793000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.scielo.br\/scielo.php?script=sci_arttext&pid=S0036-46652002000500010&lng=en&tlng=en"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2002,10]]},"references-count":16,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2002,10]]}},"alternative-id":["S0036-46652002000500010"],"URL":"https:\/\/doi.org\/10.1590\/s0036-46652002000500010","relation":{},"ISSN":["0036-4665"],"issn-type":[{"value":"0036-4665","type":"electronic"}],"subject":[],"published":{"date-parts":[[2002,10]]}}}