{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T00:18:02Z","timestamp":1792801082774,"version":"4.5.0"},"reference-count":33,"publisher":"FapUNIFESP (SciELO)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev. Inst. Med. trop. S. Paulo"],"published-print":{"date-parts":[[2009,8]]},"abstract":"<jats:p>Neurocysticercosis (NCC) has attained the importance of one of the most common cause of focal brain lesions in patients infected with HIV (human immunodeficiency virus). Adequate data regarding the rate of this co-infection is lacking. Therefore, the present study was carried out to determine the prevalence of cysticercosis among HIV patients residing in Puducherry or its neighboring districts of Tamil Nadu State, India. A total of one hundred blood samples were collected from HIV seropositive cases visiting JIPMER hospital, Puducherry, between June 2007 and May 2008. Enzyme immunotransfer blot (EITB) and enzyme linked immunosorbent assay (ELISA) were used to demonstrate anti- T. solium larval stage antibodies and Co-agglutination (Co-A) test was used to detect T. solium larval stage antigens in sera. Two HIV seropositive cases were found positive for anti-T. solium larval stage antibody by EITB and four were positive by ELISA. Only one sample was positive by both EITB and ELISA. No serum sample was found positive for T. solium larval stage antigen by Co-A test. The overall seropositivity detected by all the methods was 5% in this study group. The accurate clinical diagnosis of NCC in HIV is difficult due to deranged immunological parameters in the HIV infected patients. The results of this study provides important data on the prevalence of cysticercosis in HIV positive patients in Puducherry and neighboring areas which was previously unknown. This study will also increase awareness among physicians and public health agencies about T. solium cysticercosis in the selected group.<\/jats:p>","DOI":"10.1590\/s0036-46652009000400002","type":"journal-article","created":{"date-parts":[[2010,4,16]],"date-time":"2010-04-16T19:39:23Z","timestamp":1271446763000},"page":"185-189","source":"Crossref","is-referenced-by-count":15,"title":["A serological study of cysticercosis in patients with HIV"],"prefix":"10.1590","volume":"51","author":[{"given":"Subhash Chandra","family":"Parija","sequence":"first","affiliation":[{"name":"Jawaharlal Institute of Postgraduate Medical Education and Research, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.R.","family":"Gireesh","sequence":"additional","affiliation":[{"name":"Jawaharlal Institute of Postgraduate Medical Education and Research, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"530","reference":[{"key":"ref1","first-page":"48","article-title":"Neurocysticercosis: a review","volume":"1","author":"ANSARI J.A.","year":"2003","journal-title":"Kathmandu Univ. med. J."},{"key":"ref2","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1046\/j.1365-3156.2001.00701.x","article-title":"Detection of IgG in cerebrospinal fluid for diagnosis of NCC: evaluation of saline and SDS extracts from Taenia solium and Taenia crassiceps metacestodes by ELISA and immunoblot assay","volume":"6","author":"BARCELOS I.S.","year":"2001","journal-title":"Trop. Med. int. Hlth"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1590\/S0004-282X2000000100003","article-title":"Neurocysticercosis: detection of IgG, IgA and IgE antibodies in cerebrospinal fluid, serum and saliva samples by ELISA with Taenia solium and Taenia crassiceps antigens","volume":"58","author":"BUENO E.C.","year":"2000","journal-title":"Arq. Neuropsiquiat.","ISSN":"https:\/\/id.crossref.org\/issn\/0004-282X","issn-type":"print"},{"key":"ref4","first-page":"88","article-title":"Relationship between epilepsy and tropical diseases","volume":"35","year":"1994","journal-title":"Epilepsy","ISSN":"https:\/\/id.crossref.org\/issn\/0141-965X","issn-type":"print"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1111\/j.1708-8305.2006.00074.x","article-title":"Neurocysticercosis and human immunodeficiency virus infection: a case report","volume":"13","author":"CHIANURA L.","year":"2006","journal-title":"J. Travel Med."},{"key":"ref6","first-page":"1","article-title":"ELISA: Theory and practice","volume":"42","author":"CROWTHER J.R.","year":"1995","journal-title":"Meth. molec. Biol."},{"key":"ref7","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1212\/WNL.57.2.177","article-title":"Proposed diagnostic criteria for neurocysticercosis","volume":"57","author":"DEL BRUTTO O.H.","year":"2001","journal-title":"Neurology","ISSN":"https:\/\/id.crossref.org\/issn\/0028-3878","issn-type":"print"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1046\/j.1351-5101.2003.00696.x","article-title":"Unusual form of neurocysticercosis associated with HIV infection","volume":"11","author":"DELOBEL P.","year":"2004","journal-title":"Europ. J. Neurol."},{"key":"ref9","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1023\/A:1006366920111","article-title":"Detection of Taenia solium cysticercosis in pigs by ELISA with an excretory: secretory antigen","volume":"23","author":"D'SOUZA P.E.","year":"1999","journal-title":"Vet. Res. Commun."},{"issue":"1","key":"ref10","article-title":"Intraventricular neurocysticercosis in HIV positive patients","volume":"2","author":"FOYACA-SIBAT H","year":"2003","journal-title":"Internet J. Neurol."},{"issue":"2","key":"ref11","article-title":"Neurocysticercosis in HIV-positive patients","volume":"2","author":"FOYACA-SIBAT H","year":"2003","journal-title":"Internet J. infect. Dis."},{"key":"ref12","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1016\/S0140-6736(03)14117-7","article-title":"Taenia solium cysticercosis","volume":"362","author":"GARC\u00cdA H.H.","year":"2003","journal-title":"Lancet","ISSN":"https:\/\/id.crossref.org\/issn\/0099-5355","issn-type":"print"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1007\/s10096-002-0695-3","article-title":"Sensitivity and specificity of ELISA and immunoblot for diagnosing neurocysticercosis","volume":"21","author":"GEKELER F.","year":"2002","journal-title":"Europ. J. clin. Microbiol. infect. Dis."},{"key":"ref14","doi-asserted-by":"crossref","first-page":"1185","DOI":"10.4269\/ajtmh.1984.33.1185","article-title":"An immunoassay for the detection of circulating antigens in human echinococcosis","volume":"33","author":"GOTTSTEIN B","year":"1984","journal-title":"Amer. J. trop. Med. Hyg.","ISSN":"https:\/\/id.crossref.org\/issn\/0002-9637","issn-type":"print"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1097\/00002030-199203000-00008","article-title":"The prevalence of invasive amebiasis is not increased in patients with AIDS","volume":"6","author":"JESSURUN J","year":"1992","journal-title":"AIDS","ISSN":"https:\/\/id.crossref.org\/issn\/0269-9370","issn-type":"print"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/S0021-9258(19)52451-6","article-title":"Protein measurement with folin phenol reagent","volume":"193","author":"LOWRY O.H.","year":"1951","journal-title":"J. biol. Chem.","ISSN":"https:\/\/id.crossref.org\/issn\/0021-9258","issn-type":"print"},{"key":"ref17","first-page":"182","article-title":"Central nervous system toxoplasmosis in acquired immunodeficiency syndrome: an emerging disease in India","volume":"47","author":"MATHEW M.J.","year":"1999","journal-title":"Neurology India","ISSN":"https:\/\/id.crossref.org\/issn\/0028-3886","issn-type":"print"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1093\/qjmed\/hch080","article-title":"Management of HIV-associated focal brain lesions in developing countries","volume":"97","author":"MODI M.","year":"2004","journal-title":"Q. J. Med."},{"key":"ref19","doi-asserted-by":"crossref","first-page":"2115","DOI":"10.1128\/JCM.40.6.2115-2118.2002","article-title":"Laboratory diagnosis of human neurocysticercosis: double-blind comparison of enzyme-linked immunosorbent assay and electroimmunotransfer blot assay","volume":"40","author":"PROA\u00d1O-NARVAEZ J.V.","year":"2002","journal-title":"J.clin. Microbiol."},{"key":"ref20","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1016\/j.actatropica.2004.08.007","article-title":"Detection of specific Cysticercus antigen in the urine for diagnosis of neurocysticercosis","volume":"92","author":"PARIJA M.","year":"2004","journal-title":"Acta trop."},{"key":"ref21","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1590\/S0036-46652007000500011","article-title":"Detection of Cysticercus antigens and antibodies in cerebrospinal fluid of patients with chronic meningitis","volume":"49","author":"PARIJA S.C.","year":"2007","journal-title":"Rev. Inst. Med. trop. S. Paulo","ISSN":"https:\/\/id.crossref.org\/issn\/0036-4665","issn-type":"print"},{"key":"ref22","first-page":"283","article-title":"A serological study of human cysticercosis in Pondicherry, South India","volume":"35","author":"PARIJA S.C","year":"2003","journal-title":"J. commun. Dis."},{"key":"ref23","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1590\/S0036-46652005000400010","article-title":"Cysticercus antibodies and antigens in serum from blood donors from Pondicherry, India","volume":"47","author":"PARIJA S.C","year":"2005","journal-title":"Rev. Inst. Med. trop. S. Paulo","ISSN":"https:\/\/id.crossref.org\/issn\/0036-4665","issn-type":"print"},{"key":"ref24","series-title":"Molecular cloning: a laboratory manual","author":"SAMBROOK J.","year":"1989","edition":"2"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"113","DOI":"10.4269\/ajtmh.2007.77.113","article-title":"Neurocysticercosis in the HIV era: a case report and review of the literature","volume":"77","author":"SERPA J.A.","year":"2007","journal-title":"Amer. J. trop. Med. Hyg.","ISSN":"https:\/\/id.crossref.org\/issn\/0002-9637","issn-type":"print"},{"key":"ref26","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1099\/00222615-38-6-391","article-title":"Co-agglutination (Co-A) test for circulating antigen in hydatid disease","volume":"38","author":"SHARIFF G.M.","year":"1993","journal-title":"J. med. Microbiol."},{"key":"ref27","first-page":"85","article-title":"Enzyme-linked immuno electro transfer blot in diagnosis of Taenia solium cysticercosis in pigs","volume":"23","author":"SREENIVASAMURTHY G.S.","year":"1999","journal-title":"J. paras. Dis."},{"key":"ref28","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/0090-3019(95)00259-6","article-title":"Neurocysticercosis and HIV infection: report of two cases and review","volume":"45","author":"SOTO-HERNANDEZ J.L.","year":"1996","journal-title":"Surg. Neurol."},{"key":"ref29","doi-asserted-by":"crossref","first-page":"963","DOI":"10.1001\/archneur.1992.00530330087021","article-title":"Neurocysticercosis and human immunodeficiency virus infection: a possible association","volume":"49","author":"THORNTON C.A.","year":"1992","journal-title":"Arch. Neurol."},{"key":"ref30","doi-asserted-by":"crossref","first-page":"4350","DOI":"10.1073\/pnas.76.9.4350","article-title":"Electrophoretic transfer of proteins from polyacrylamide gel to nitrocellulose sheets: procedure and cone applications","volume":"76","author":"TOWBIN H.","year":"1979","journal-title":"Proc. nat. Acad. Sci.","ISSN":"https:\/\/id.crossref.org\/issn\/0027-8424","issn-type":"print"},{"key":"ref31","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1093\/infdis\/159.1.50","article-title":"An enzyme-linked immunoelectrotransfer blot assay and glycoprotein antigens for diagnosing human cysticercosis (Taenia solium)","volume":"159","author":"TSANG V.C.","year":"1989","journal-title":"J. infect. Dis.","ISSN":"https:\/\/id.crossref.org\/issn\/0022-1899","issn-type":"print"},{"key":"ref32","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/S0002-9343(99)80113-2","article-title":"Asymptomatic neurocysticercosis in a patient with AIDS and cryptococcal meningitis","volume":"99","author":"WHITE Jr. A.C.","year":"1995","journal-title":"Amer. J. Med."},{"key":"ref33","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1159\/000058663","article-title":"Taenia solium cysticercosis: host-parasite interactions and the immune response","volume":"66","author":"WHITE Jr. A.C.","year":"1997","journal-title":"Chem. Immunol"}],"container-title":["Revista do Instituto de Medicina Tropical de S\u00e3o Paulo"],"original-title":[],"link":[{"URL":"http:\/\/www.scielo.br\/pdf\/rimtsp\/v51n4\/v51n4a02.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,10,26]],"date-time":"2021-10-26T06:09:40Z","timestamp":1635228580000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.scielo.br\/scielo.php?script=sci_arttext&pid=S0036-46652009000400002&lng=en&tlng=en"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,8]]},"references-count":33,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2009,8]]}},"alternative-id":["S0036-46652009000400002"],"URL":"https:\/\/doi.org\/10.1590\/s0036-46652009000400002","relation":{},"ISSN":["0036-4665"],"issn-type":[{"value":"0036-4665","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,8]]}}}