{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T19:35:19Z","timestamp":1775072119373,"version":"3.50.1"},"reference-count":28,"publisher":"FapUNIFESP (SciELO)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev. Inst. Med. trop. S. Paulo"],"published-print":{"date-parts":[[2010,2]]},"abstract":"<jats:p>Yellow fever (YF) is an acute viral infectious disease transmitted by mosquitoes which occurs in two distinct epidemiological cycles: sylvatic and urban. In the sylvatic cycle, the virus is maintained by monkey's infection and transovarian transmission in vectors. Surveillance of non-human primates is required for the detection of viral circulation during epizootics, and for the identification of unaffected or transition areas. An ELISA (enzyme-linked immunosorbent assay) was standardized for estimation of the prevalence of IgG antibodies against yellow fever virus in monkey sera (Alouatta caraya) from the reservoir area of Porto Primavera Hydroelectric Plant, in the state of S\u00e3o Paulo, Brazil. A total of 570 monkey sera samples were tested and none was reactive to antibodies against yellow fever virus. The results corroborate the epidemiology of yellow fever in the area. Even though it is considered a transition area, there were no reports to date of epizootics or yellow fever outbreaks in humans. Also, entomological investigations did not detect the presence of vectors of this arbovirus infection. ELISA proved to be fast, sensitive, an adequate assay, and an instrument for active search in the epidemiological surveillance of yellow fever allowing the implementation of prevention actions, even before the occurrence of epizootics.<\/jats:p>","DOI":"10.1590\/s0036-46652010000100002","type":"journal-article","created":{"date-parts":[[2010,4,16]],"date-time":"2010-04-16T15:15:45Z","timestamp":1271430945000},"page":"11-16","source":"Crossref","is-referenced-by-count":15,"title":["Circulation of antibodies against yellow fever virus in a simian population in the area of Porto Primavera Hydroelectric Plant, S\u00e3o Paulo, Brazil"],"prefix":"10.1590","volume":"52","author":[{"given":"Maura Antonia","family":"Lima","sequence":"first","affiliation":[{"name":"University of S\u00e3o Paulo, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicolina Silvana","family":"Romano-Lieber","sequence":"additional","affiliation":[{"name":"University of S\u00e3o Paulo, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana Maria Ribeiro de Castro","family":"Duarte","sequence":"additional","affiliation":[{"name":"Superintend\u00eancia de Controle de Endemias, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"530","reference":[{"key":"ref1","series-title":"Estudo sobre a infec\u00e7\u00e3o por Flavivirus brasileiros em macr\u00f3fagos de camundongos","author":"Barros VED","year":"2002"},{"key":"ref2","first-page":"187","article-title":"Recuperaci\u00f3n de v\u00edrus amar\u00edlico procedente de un mono centinela, en las cercanias de Bel\u00e9m, Brasil","volume":"60","author":"Bensabath G","year":"1966","journal-title":"Bol Ofic Sanit Panam"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"339","DOI":"10.4269\/ajtmh.1967.16.339","article-title":"Production and characterization of arbovirus antibody in mouse ascitic fluid","volume":"16","author":"Brandt WE","year":"1967","journal-title":"Am J Trop Med Hyg","ISSN":"https:\/\/id.crossref.org\/issn\/0002-9637","issn-type":"print"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"1278","DOI":"10.1590\/S0102-311X2005000400031","article-title":"Entomological investigation of a sylvatic yellow fever area in S\u00e3o Paulo State, Brazil","volume":"21","author":"Camargo-Neves VLF","year":"2005","journal-title":"Cad Sa\u00fade P\u00fablica"},{"key":"ref5","series-title":"Guide to the care and use of experimental animals","first-page":"1980"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1590\/S0034-89101987000300004","article-title":"Investiga\u00e7\u00e3o epidemiol\u00f3gica de casos de febre amarela na regi\u00e3o noroeste do Estado de S\u00e3o Paulo, Brasil","volume":"21","author":"Coimbra TLM","year":"1987","journal-title":"Rev Sa\u00fade P\u00fablica"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1016\/j.actatropica.2006.09.010","article-title":"Malaria epidemiology in low-endemicity areas of the Atlantic Forest in the Vale do Ribeira, S\u00e3o Paulo, Brazil","volume":"100","author":"Curado I","year":"2006","journal-title":"Acta Trop","ISSN":"https:\/\/id.crossref.org\/issn\/0001-706X","issn-type":"print"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1093\/oxfordjournals.aje.a113835","article-title":"Susceptibility of Capuchin (Cebus) monkeys to yellow fever virus","volume":"11","author":"Davis NC","year":"1930","journal-title":"Am J. 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Preliminary observations","volume":"50","author":"Davis NC","year":"1929","journal-title":"J Exp Med","ISSN":"https:\/\/id.crossref.org\/issn\/0022-1007","issn-type":"print"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"565","DOI":"10.4269\/ajtmh.1983.32.565","article-title":"Comparison of the enzyme-linked immunosorbent assay (ELISA) with standard tests used to detect yellow fever virus antibodies","volume":"32","author":"Deubel V","year":"1983","journal-title":"Amer J Trop Med Hyg","ISSN":"https:\/\/id.crossref.org\/issn\/0002-9637","issn-type":"print"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1111\/j.1600-0684.2006.00148.x","article-title":"Widespread occurrence of antibodies against circumsporozoite protein and against blood forms of Plasmodium vivax, P. falciparum and P. malariae in Brazilian wild monkeys","volume":"35","author":"Duarte AM","year":"2006","journal-title":"J Med Primatol","ISSN":"https:\/\/id.crossref.org\/issn\/0047-2565","issn-type":"print"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1590\/S0037-86821990000100003","article-title":"Uso de c\u00e9lulas de Aedes albopictus C6\/36 na propaga\u00e7\u00e3o e classifica\u00e7\u00e3o de arbov\u00edrus das fam\u00edlias Togaviridae, Flaviviridae, Bunyaviridae e Rhabdoviridae","volume":"23","author":"Figueiredo LTM","year":"1990","journal-title":"Rev Soc Bras Med Trop","ISSN":"https:\/\/id.crossref.org\/issn\/0037-8682","issn-type":"print"},{"key":"ref13","first-page":"1","article-title":"Aspectos ecol\u00f3gicos e vetoriais da febre amarela silvestre no Rio Grande do Sul","volume":"10","author":"Gomes AC","year":"2008","journal-title":"Bol Epidemiol Centro Estadual Vigil\u00e2ncia em Sa\u00fade\/RS"},{"key":"ref14","series-title":"The arboviruses: epidemiology and ecology","first-page":"77","volume-title":"Rocio encephalitis","volume":"4","author":"Iversson LB","year":"1988"},{"key":"ref15","first-page":"164","article-title":"Use of immunoglobulin M antibody capture enzyme linked immunosorbent assay in the surveillance of Rocio encephalitis","volume":"44","author":"Iversson LB","year":"1992","journal-title":"Ci\u00ean. Cult"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1590\/S0037-86822004000600003","article-title":"Padroniza\u00e7\u00e3o da t\u00e9cnica imunoenzim\u00e1tica do ELISA de captura, no sistema avidina-biotina para a identifica\u00e7\u00e3o de sangue ingerido por Lutzomia (Lutzomia) longipalpis (Lutz & Neiva, 1912)","volume":"37","author":"Marass\u00e1 AM","year":"2004","journal-title":"Rev Soc Bras Med Trop","ISSN":"https:\/\/id.crossref.org\/issn\/0037-8682","issn-type":"print"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/S1473-3099(01)00016-0","article-title":"Yellow fever: an update","volume":"1","author":"Monath TP","year":"2001","journal-title":"Lancet Infect Dis"},{"key":"ref18","series-title":"The arboviruses: ecology and epidemiology","first-page":"139","volume-title":"Yellow fever","volume":"5","author":"Monath TP","year":"1988"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"151","DOI":"10.4269\/ajtmh.1984.33.151","article-title":"Detection of yellow fever virus in serum by enzyme immunoassay","volume":"33","author":"Monath TP","year":"1984","journal-title":"Am. 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