{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T20:45:50Z","timestamp":1780433150831,"version":"3.54.1"},"reference-count":16,"publisher":"FapUNIFESP (SciELO)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev. Inst. Med. trop. S. Paulo"],"published-print":{"date-parts":[[2010,8]]},"abstract":"<jats:p>Botulism is a rare and potentially lethal illness caused by Clostridium botulinum neurotoxin. We describe the findings of a laboratorial investigation of 117 suspected cases of botulism reported to the surveillance system in Brazil from January 2000 to October 2008. Data on the number and type of samples analyzed, type of toxins identified, reporting of the number of botulism cases and transmission sources are discussed. A total of 193 clinical samples and 81 food samples were analyzed for detection and identification of the botulism neurotoxin. Among the clinical samples, 22 (11.4%) presented the toxin (nine type A, five type AB and eight with an unidentified type); in food samples, eight (9.9%) were positive for the toxin (five type A, one type AB and two with an unidentified type). Of the 38 cases of suspected botulism in Brazil, 27 were confirmed by a mouse bioassay. Laboratorial botulism diagnosis is an important procedure to elucidate cases, especially food-borne botulism, to confirm clinical diagnosis and to identify toxins in food, helping sanitary control measures.<\/jats:p>","DOI":"10.1590\/s0036-46652010000400003","type":"journal-article","created":{"date-parts":[[2010,9,8]],"date-time":"2010-09-08T13:51:27Z","timestamp":1283953887000},"page":"183-186","source":"Crossref","is-referenced-by-count":16,"title":["Botulism in Brazil, 2000-2008: epidemiology, clinical findings and laboratorial diagnosis"],"prefix":"10.1590","volume":"52","author":[{"given":"Ruth Estela Gravato","family":"Rowlands","sequence":"first","affiliation":[{"name":"Adolfo Lutz Institute,  Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christiane Asturiano","family":"Ristori","sequence":"additional","affiliation":[{"name":"Adolfo Lutz Institute,  Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giselle Ibette S. Lopez","family":"Lopes","sequence":"additional","affiliation":[{"name":"Adolfo Lutz Institute,  Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana Maria Ramalho de","family":"Paula","sequence":"additional","affiliation":[{"name":"Adolfo Lutz Institute,  Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Harumi","family":"Sakuma","sequence":"additional","affiliation":[{"name":"Adolfo Lutz Institute,  Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raquel","family":"Grigaliunas","sequence":"additional","affiliation":[{"name":"Adolfo Lutz Institute,  Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roberto","family":"Lopreato Filho","sequence":"additional","affiliation":[{"name":"Adolfo Lutz Institute,  Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dilma Scala","family":"Gelli","sequence":"additional","affiliation":[{"name":"Adolfo Lutz Institute,  Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria Bernadete de Paula","family":"Eduardo","sequence":"additional","affiliation":[{"name":"Center for Epidemiologic Surveillance,  Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miyoko","family":"Jakabi","sequence":"additional","affiliation":[{"name":"Adolfo Lutz Institute,  Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"530","reference":[{"key":"ref1","series-title":"Bacterial infections of humans: epidemiology and control","first-page":"139","volume-title":"Botulism","author":"Angulo FJ","year":"1999"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"1059","DOI":"10.1001\/jama.285.8.1059","article-title":"Botulinum toxin as a biological weapon: medical and public health management","volume":"285","author":"Arnon SS","year":"2001","journal-title":"JAMA","ISSN":"https:\/\/id.crossref.org\/issn\/0098-7484","issn-type":"print"},{"issue":"46","key":"ref3","first-page":"1","article-title":"Botulismo associado a alimentos comerciais assados doados, munic\u00edpio de S\u00e3o Vicente, SP - 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