{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,4,27]],"date-time":"2023-04-27T14:33:35Z","timestamp":1682606015599},"reference-count":35,"publisher":"FapUNIFESP (SciELO)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev. Inst. Med. trop. S. Paulo"],"published-print":{"date-parts":[[2014,7]]},"abstract":"<jats:p>The favorable outcome of the treatment of a disease is influenced by the adherence to therapy. Our objective was to assess factors associated with adherence to treatment of patients included in a clinical trial of equivalence between the standard and alternative treatment schemes with meglumine antimoniate (MA) in the treatment of cutaneous leishmaniasis (CL), in the state of Rio de Janeiro. Between 2008 and 2011, 57 patients with CL were interviewed using a questionnaire to collect socioeconomic data. The following methods were used for adherence monitoring: counting of vial surplus, monitoring card, Morisky test and modified Morisky test (without the question regarding the schedule); we observed 82.1% (vial return), 86.0% (monitoring card), 66.7% (Morisky test) and 86.0% (modified Morisky test) adherence. There was a strong correlation between the method of vial counting and the monitoring card and modified Morisky test. A significant association was observed between greater adherence to treatment and low dose of MA, as well as with a lower number of people sleeping in the same room. We recommend the use of the modified Morisky test to assess adherence to treatment of CL with MA, because it is a simple method and with a good performance, when compared to other methods.<\/jats:p>","DOI":"10.1590\/s0036-46652014000400004","type":"journal-article","created":{"date-parts":[[2014,7,28]],"date-time":"2014-07-28T13:22:20Z","timestamp":1406553740000},"page":"291-296","source":"Crossref","is-referenced-by-count":7,"title":["FACTORS ASSOCIATED TO ADHERENCE TO DIFFERENT TREATMENT SCHEMES WITH MEGLUMINE ANTIMONIATE IN A CLINICAL TRIAL FOR CUTANEOUS LEISHMANIASIS"],"prefix":"10.1590","volume":"56","author":[{"given":"Madelon Novato","family":"Ribeiro","sequence":"first","affiliation":[{"name":"Instituto de Pesquisas Evandro Chagas, IPEC\/FIOCRUZ,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria In\u00eas Fernandes","family":"Pimentel","sequence":"additional","affiliation":[{"name":"Instituto de Pesquisas Evandro Chagas, IPEC\/FIOCRUZ,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Armando de Oliveira","family":"Schubach","sequence":"additional","affiliation":[{"name":"Instituto de Pesquisas Evandro Chagas, IPEC\/FIOCRUZ,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raquel de Vasconcellos Carvalh\u00e3es de","family":"Oliveira","sequence":"additional","affiliation":[{"name":"Instituto de Pesquisas Evandro Chagas, IPEC\/FIOCRUZ,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jos\u00e9 Liporage","family":"Teixeira","sequence":"additional","affiliation":[{"name":"Instituto de Pesquisas Evandro Chagas, IPEC\/FIOCRUZ,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Madson Pedro da Silva","family":"Leite","sequence":"additional","affiliation":[{"name":"Instituto de Pesquisas Evandro Chagas, IPEC\/FIOCRUZ,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Monique","family":"Fonseca","sequence":"additional","affiliation":[{"name":"Instituto de Pesquisas Evandro Chagas, IPEC\/FIOCRUZ,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ginelza Peres Lima dos","family":"Santos","sequence":"additional","affiliation":[{"name":"Instituto de Pesquisas Evandro Chagas, IPEC\/FIOCRUZ,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mariza Matos","family":"Salgueiro","sequence":"additional","affiliation":[{"name":"Instituto de Pesquisas Evandro Chagas, IPEC\/FIOCRUZ,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Erica de Camargo Ferreira e","family":"Vasconcellos","sequence":"additional","affiliation":[{"name":"Instituto de Pesquisas Evandro Chagas, IPEC\/FIOCRUZ,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marcelo Rosandiski","family":"Lyra","sequence":"additional","affiliation":[{"name":"Instituto de Pesquisas Evandro Chagas, IPEC\/FIOCRUZ,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mauricio Naoto","family":"Saheki","sequence":"additional","affiliation":[{"name":"Instituto de Pesquisas Evandro Chagas, IPEC\/FIOCRUZ,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claudia Maria","family":"Valete-Rosalino","sequence":"additional","affiliation":[{"name":"Instituto de Pesquisas Evandro Chagas, IPEC\/FIOCRUZ,  Brazil; Universidade Federal do Rio de Janeiro, UFRJ,  Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"530","reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"1269","DOI":"10.1016\/S0020-7519(00)00136-3","article-title":"The leishmaniasis as emerging and reemerging zoonoses","volume":"30","author":"Ashford RW","year":"2000","journal-title":"Int J Parasitol"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1590\/S0037-86822002000500009","article-title":"An intermittent schedule is better than continuous regimen of antimonial therapy for cutaneous leishmaniasis in the municipality of Rio de Janeiro, Brazil","volume":"35","author":"Azeredo-Coutinho RB","year":"2002","journal-title":"Rev Soc Bras Med Trop"},{"key":"ref3","series-title":"Currency conversion"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/0035-9203(88)90267-2","article-title":"Pharmacokinetics of antimony during treatment of visceral leishmaniasis with sodium stibogluconate or meglumine antimoniate","volume":"82","author":"Chulay JD","year":"1988","journal-title":"Trans R Soc Trop Med Hyg"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/0277-9536(85)90308-9","article-title":"The meaning of medication: another look at compliance","volume":"20","author":"Conrad P","year":"1985","journal-title":"Soc Sci Med"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"3273","DOI":"10.1001\/jama.1989.03420220087032","article-title":"How often is medication taken as prescribed? 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