{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,2]],"date-time":"2025-11-02T16:37:01Z","timestamp":1762101421013},"reference-count":25,"publisher":"FapUNIFESP (SciELO)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev. Soc. Bras. Med. Trop."],"published-print":{"date-parts":[[1992,3]]},"abstract":"<jats:p>Foi feito o estudo quantitativo de mast\u00f3citos e de granul\u00f3citos eosin\u00f3filos no mioc\u00e1rdio de 40 ratos albinos Wistar. Trinta animais encontravam-se nafase tardia da infec\u00e7\u00e3o (8\u00ba m\u00eas) produzida pelas cepas S\u00e3o Felipe, Y e Colombiana do Trypanosoma cruzi, e apresentavam graus vari\u00e1veis de miocardite cr\u00f4nica; 10 ratos serviram como controles. Miocardite cr\u00f4nica fibrosante (fibrose) ocorreu em 40% dos animais infectados e detectou-se aumento do n\u00famero de mast\u00f3citos nos animais, chag\u00e1sicos, o qual se associou \u00e0 infec\u00e7\u00e3o mas n\u00e3o \u00e0 fibrose mioc\u00e1rdica. N\u00e3o se constatou aumento do n\u00famero de eosin\u00f3filos.<\/jats:p>","DOI":"10.1590\/s0037-86821992000100007","type":"journal-article","created":{"date-parts":[[2013,4,24]],"date-time":"2013-04-24T14:07:29Z","timestamp":1366812449000},"page":"45-50","source":"Crossref","is-referenced-by-count":6,"title":["An\u00e1lise quantitativa de mast\u00f3citos e de granul\u00f3citos eosin\u00f3filos no mioc\u00e1rdio de ratos wistar cronicamente infectados pelo Trypanosoma cruzi. Contribui\u00e7\u00e3o ao conhecimento da fibrose mioc\u00e1rdia"],"prefix":"10.1590","volume":"25","author":[{"given":"Maria da Concei\u00e7\u00e3o Nascimento","family":"Pinheiro","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paulo S\u00e9rgio Siebra","family":"Beraldo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luiz Fernando","family":"Junqueira J\u00fanior","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Edison Reis","family":"Lopes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Edmundo","family":"Chapadeiro","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"530","reference":[{"key":"ref1","series-title":"Contribui\u00e7\u00e3o ao estudo da anatomia patol\u00f3gica e da patog\u00eanese do megaes\u00f4fago chag\u00e1sico","author":"Adad SJ","year":"1989"},{"key":"ref2","first-page":"5","article-title":"Estudo quantitativo dos mast\u00f3citos nacardiopatiachag\u00e1sica cr\u00f4nica","volume":"17","author":"Almeida HO","year":"1975","journal-title":"Revista do Instituto de Medicina Tropical de S\u00e3o Paulo","ISSN":"http:\/\/id.crossref.org\/issn\/0036-4665","issn-type":"print"},{"key":"ref3","first-page":"893","article-title":"Histological studies of the reactions of cells and intercelular substances of loose connective tissue to the spreading factor of testicular extracts","volume":"51","author":"Bensley SH","year":"1949","journal-title":"Annals of the New York Academy of Sciences","ISSN":"http:\/\/id.crossref.org\/issn\/0077-8923","issn-type":"print"},{"key":"ref4","first-page":"479","article-title":"As causas anat\u00f4micas da insufici\u00eancia card\u00edaca na cardiopatia (miocardite) chag\u00e1sica cr\u00f4nica, estudadas comparativamente com as causas anat\u00f4micas da insufici\u00eancia card\u00edaca noutras cardiopatias. Parte II","volume":"29","author":"Bogliolo L","year":"1976","journal-title":"Arquivos Brasileiros de Cardiologia","ISSN":"http:\/\/id.crossref.org\/issn\/0066-782X","issn-type":"print"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1590\/S0037-86821988000300002","article-title":"Les\u00f5es card\u00edacas em ratos Wistar inoculados com diferentes cepas do Trypanosoma cruzi","volume":"21","author":"Chapadeiro E","year":"1988","journal-title":"Revista da Sociedade Brasileira de Medicina Tropical","ISSN":"http:\/\/id.crossref.org\/issn\/0037-8682","issn-type":"print"},{"key":"ref6","first-page":"269","article-title":"Contribution a l'\u00e9tudephysio-patologique des mastocytes dans le myocarde","volume":"9","author":"Femex M","year":"1960","journal-title":"Actualit\u00e9 Cardiologie et Angiologie"},{"key":"ref7","series-title":"Nonparametric statistical methods","author":"Hollander M","year":"1973"},{"key":"ref8","first-page":"1035","article-title":"Chagas'disease","volume":"14","author":"Laranja FS","year":"1956","journal-title":"A clinical, epidemiologic and pathologic study. Circulation"},{"key":"ref9","series-title":"Bogliolo Patologia","first-page":"1047","volume-title":"Patologia das principais doen\u00e7as tropicais no Brasil","author":"Lopes ER","year":"1987","edition":"4"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1093\/ajcp\/48.1.39","article-title":"Chronic Chagasic myocarditis","volume":"48","author":"Lorenzana R","year":"1967","journal-title":"Report of a case. American Journal of Clinical Pathology"},{"key":"ref11","first-page":"1","article-title":"Primer caso cr\u00f4nico de forma card\u00edaca de enfermidad de Chagas demonstrado en Santiago del Estero","volume":"38","author":"Mazza S","year":"1938","journal-title":"Publicaci\u00f3n de la Mision de Estudios de Patologia Regional Argentina"},{"key":"ref12","first-page":"187","article-title":"Os mast\u00f3citos da pele de camundongos infectados experimentalmente com Trypanosoma cruzi","volume":"68","author":"Menezes H","year":"1965","journal-title":"O Hospital"},{"key":"ref13","series-title":"Alguns aspectos da anatomia patol\u00f3gica da cardite chag\u00e1sica cr\u00f4nica","author":"Mignone C","year":"1958"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"1297","DOI":"10.1016\/0020-7519(87)90095-6","article-title":"A study of human myocardial tissue in Chagas'disease: Distribution and frequency of inflammatory cell types","volume":"17","author":"Molina HA","year":"1987","journal-title":"International Journal ofParasitology"},{"key":"ref15","first-page":"725","article-title":"Immunohistochemical detection of deposits of eosinophil-derived neurotoxin and eosinophil peroxidase in the myocardium of patients with Chagas'disease","volume":"64","author":"Molina HA","year":"1988","journal-title":"Immunology","ISSN":"http:\/\/id.crossref.org\/issn\/0019-2805","issn-type":"print"},{"key":"ref16","first-page":"289","article-title":"Interaction of human eosinophils or neutrophils with Trypanosoma cruzi in vitro causes bystander cardiac cell damage","volume":"66","author":"Molina HA","year":"1989","journal-title":"Immunology","ISSN":"http:\/\/id.crossref.org\/issn\/0019-2805","issn-type":"print"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"129","DOI":"10.2307\/3282950","article-title":"Eosinophil activation in acute and chronic myocardial lesions and deposition of toxin eosinophil granule proteins on heart myofibers","volume":"75","author":"Molina HA","year":"1989","journal-title":"Journal ofParasitology"},{"key":"ref18","first-page":"107","article-title":"The formation of collagen fibres by theaction of heparin an soluble collagen","volume":"96","author":"Morrione TG","year":"1952","journal-title":"An electron microscope study. Journal of Experimental Medicine"},{"key":"ref19","first-page":"319","article-title":"The pathophysiology of endomyocardial fibrosis","volume":"38","author":"Olsen EGJ","year":"1982","journal-title":"Arquivos Brasileiros de Cardiologia","ISSN":"http:\/\/id.crossref.org\/issn\/0066-782X","issn-type":"print"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"622","DOI":"10.1007\/BF00344004","article-title":"Das zerfallastadium un die folgen der mastzelledegamullerung mit besonderer beruckschtigeng der mesenchymalen reaktion","volume":"61","author":"Orfanos C","year":"1963","journal-title":"Zeitschrift f\u00fcr Zellforschung und Mikroskopische Anatomie"},{"key":"ref21","first-page":"30","article-title":"Estudo quantitativo dos mast\u00f3citos na musculatura do es\u00f4fago de chag\u00e1sicos cr\u00f4nicos","volume":"14","author":"Pereira FEL","year":"1972","journal-title":"Revista do Instituto de Medicina Tropical de S\u00e3o Paulo","ISSN":"http:\/\/id.crossref.org\/issn\/0036-4665","issn-type":"print"},{"key":"ref22","series-title":"Enfermedadde Chagas","author":"Romana C","year":"1963"},{"key":"ref23","first-page":"149","article-title":"Les\u00f5es dos plexos de Meissner e de Auerbach do intestino do camundongo albino na fase cr\u00f4nica da tripanossom\u00edase cruzi experimental","volume":"9","author":"Tafuri WL","year":"1967","journal-title":"Revista do Instituto de Medicina Tropical de S\u00e3o Paulo","ISSN":"http:\/\/id.crossref.org\/issn\/0036-4665","issn-type":"print"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1590\/S0037-86821983000200010","article-title":"Miocardite chag\u00e1sica aguda humana: Prov\u00e1vel agress\u00e3o \u00e0 c\u00e9lula card\u00edaca pelo granul\u00f3cito eosin\u00f3filo","volume":"16","author":"Tafuri WL","year":"1983","journal-title":"Revista da Sociedade Brasileira de Medicina Tropical","ISSN":"http:\/\/id.crossref.org\/issn\/0037-8682","issn-type":"print"},{"key":"ref25","series-title":"Manifesta\u00e7\u00f5es digestivas da mol\u00e9stia de Chagas","first-page":"60","volume-title":"Anatomia Patol\u00f3gica","author":"Tafuri WL","year":"1983","edition":"1"}],"container-title":["Revista da Sociedade Brasileira de Medicina Tropical"],"original-title":[],"link":[{"URL":"http:\/\/www.scielo.br\/pdf\/rsbmt\/v25n1\/07.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,5,27]],"date-time":"2017-05-27T13:01:04Z","timestamp":1495890064000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.scielo.br\/scielo.php?script=sci_arttext&pid=S0037-86821992000100007&lng=pt&tlng=pt"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1992,3]]},"references-count":25,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1992,3]]}},"alternative-id":["S0037-86821992000100007"],"URL":"https:\/\/doi.org\/10.1590\/s0037-86821992000100007","relation":{},"ISSN":["0037-8682"],"issn-type":[{"value":"0037-8682","type":"electronic"}],"subject":[],"published":{"date-parts":[[1992,3]]}}}