{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T19:31:07Z","timestamp":1760297467503},"reference-count":39,"publisher":"FapUNIFESP (SciELO)","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev. Soc. Bras. Med. Trop."],"published-print":{"date-parts":[[2002,12]]},"abstract":"<jats:p>The effects of high and low-protein diets on the structure of the jejunal mucosa were studied in Schistosoma mansoni infected mice (morphology and histomorphometry). Weaning male albino mice were infected with 80 cercariae, fed with high (20%) or low-protein (5%) diets and compared to uninfected controls under the same conditions. Mice were sacrificed 12 weeks after infection. Animals submitted to a low-protein diet showed lower weight curves, mainly when infected. In the jejunal mucosa, finger-like villi were the predominant pattern among uninfected high-protein fed animals, while the infected ones showed leaf-shaped and flattened villi in most cases. Undernourished infected mice had 65.7% leaf-shaped villi. A significant increase in the number of goblet cells was seen in infected mice. A decrease in the number of absorptive cells was detected in undernourished mice, particularly in infected ones.<\/jats:p>","DOI":"10.1590\/s0037-86822002000600010","type":"journal-article","created":{"date-parts":[[2005,4,26]],"date-time":"2005-04-26T16:49:43Z","timestamp":1114534183000},"page":"601-607","source":"Crossref","is-referenced-by-count":8,"title":["Structural changes in the jejunal mucosa of mice infected with Schistosoma mansoni, fed low or high protein diets"],"prefix":"10.1590","volume":"35","author":[{"given":"Janira L\u00facia Assump\u00e7\u00e3o","family":"Couto","sequence":"first","affiliation":[{"name":"Universidade Federal de Alagoas"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Haroldo da Silva","family":"Ferreira","sequence":"additional","affiliation":[{"name":"Universidade Federal de Alagoas, AL"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dinalva Bezerra da","family":"Rocha","sequence":"additional","affiliation":[{"name":"Escola de Ci\u00eancias M\u00e9dicas de Alagoas"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria Eug\u00eania Leite","family":"Duarte","sequence":"additional","affiliation":[{"name":"Universidade Federal Fluminense"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Monica Lopes","family":"Assun\u00e7\u00e3o","sequence":"additional","affiliation":[{"name":"Universidade Federal de Alagoas, AL"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eridan de Medeiros","family":"Coutinho","sequence":"additional","affiliation":[{"name":"Funda\u00e7\u00e3o Oswaldo Cruz, Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"530","reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1093\/infdis\/132.1.6","article-title":"Calorie and protein malnutrition in chronic murine schistosomiasis mansoni: effect on the parasite and the 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