{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T03:18:50Z","timestamp":1787023130388,"version":"build-2736575974"},"reference-count":23,"publisher":"FapUNIFESP (SciELO)","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev. Soc. Bras. Med. Trop."],"published-print":{"date-parts":[[2002,12]]},"abstract":"<jats:p>A grande incid\u00eancia de criptococose em decorr\u00eancia do aumento crescente de indiv\u00edduos imunodeprimidos e os efeitos colaterais aos f\u00e1rmacos utilizados para o tratamento desta infec\u00e7\u00e3o, tem incentivado a pesquisa de novos agentes antif\u00fangicos. Atrav\u00e9s da t\u00e9cnica de dilui\u00e7\u00e3o em \u00e1gar, foi verificada a atividade antif\u00fangica (in vitro) de diferentes constituintes de Caryocar brasiliensis sobre Cryptococcus neoformans. Verificou-se que a cera epicuticular retirada da folha, coletada em per\u00edodo de baixo \u00edndice pluviom\u00e9trico (170,8mm de \u00e1gua), foi a parte mais ativa da planta, inibindo o crescimento de 91,3% (21\/23) dos isolados de Cryptococcus neoformans em concentra\u00e7\u00e3o &lt; a 250\u00b5g\/mL.<\/jats:p>","DOI":"10.1590\/s0037-86822002000600013","type":"journal-article","created":{"date-parts":[[2005,4,26]],"date-time":"2005-04-26T12:49:43Z","timestamp":1114519783000},"page":"623-627","source":"Crossref","is-referenced-by-count":26,"title":["Atividade antif\u00fangica de Caryocar brasiliensis (Caryocaraceae) sobre Cryptococcus neoformans"],"prefix":"10.1590","volume":"35","author":[{"given":"Xisto Sena","family":"Passos","sequence":"first","affiliation":[{"name":"Universidade Federal de Goi\u00e1s"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suzana da Costa","family":"Santos","sequence":"additional","affiliation":[{"name":"Universidade Federal de Goi\u00e1s"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pedro Henrique","family":"Ferri","sequence":"additional","affiliation":[{"name":"Universidade Federal de Goi\u00e1s"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Orionalda de F\u00e1tima Lisboa","family":"Fernandes","sequence":"additional","affiliation":[{"name":"Universidade Federal de Goi\u00e1s"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thaliana de Freitas","family":"Paula","sequence":"additional","affiliation":[{"name":"Universidade Federal de Goi\u00e1s"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana Cristina Ferreira","family":"Garcia","sequence":"additional","affiliation":[{"name":"Universidade Federal de Goi\u00e1s"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria do Ros\u00e1rio Rodrigues","family":"Silva","sequence":"additional","affiliation":[{"name":"Universidade Federal de Goi\u00e1s"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"530","reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1590\/S0036-46651992000300012","article-title":"Sensibilidade de leveduras do g\u00eanero Candida isoladas de pacientes com c\u00e2ncer, a antif\u00fangicos poli\u00eanicos","volume":"34","author":"Alves SH","year":"1992","journal-title":"Revista do Instituto de Medicina Tropical de S\u00e3o Paulo","ISSN":"https:\/\/id.crossref.org\/issn\/0036-4665","issn-type":"print"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1590\/S0074-02762000000300012","article-title":"Biological screening of Brazilian medicinal plants","volume":"95","author":"Alves TMA","year":"2000","journal-title":"Mem\u00f3rias do Instituto Oswaldo Cruz","ISSN":"https:\/\/id.crossref.org\/issn\/0074-0276","issn-type":"print"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1007\/BF02862276","article-title":"A review of Caryocar brasiliensis (Caryocaraceae) - An economically valuable species of the Central Brazilian Cerrados","volume":"49","author":"Araujo FD","year":"1995","journal-title":"Economy Botany"},{"key":"ref4","first-page":"224","article-title":"Compostas. 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