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Enquanto que o v\u00edrus HTLV-1 est\u00e1 relacionado com uma alta produ\u00e7\u00e3o de IFN-\u03b3 e desvio da resposta imune para o tipo Th1, a prote\u00e7\u00e3o contra helmintos est\u00e1 associada a uma resposta Th2. Devido a este vi\u00e9s da resposta imune, indiv\u00edduos infectados pelo HTLV-1 apresentam redu\u00e7\u00e3o na produ\u00e7\u00e3o de IL-4, IL-5, IL-13 e IgE, componentes participantes dos mecanismos de defesa contra S. stercoralis. Estas anormalidades constituem a base para a ocorr\u00eancia de maior freq\u00fc\u00eancia e de formas mais graves da estrongiloid\u00edase em pacientes infectados pelo HTLV-1.<\/jats:p>","DOI":"10.1590\/s0037-86822002000600016","type":"journal-article","created":{"date-parts":[[2005,4,26]],"date-time":"2005-04-26T16:49:43Z","timestamp":1114534183000},"page":"641-649","source":"Crossref","is-referenced-by-count":29,"title":["Implica\u00e7\u00f5es cl\u00ednicas e imunol\u00f3gicas da associa\u00e7\u00e3o entre o HTLV-1 e a estrongiloid\u00edase"],"prefix":"10.1590","volume":"35","author":[{"given":"Maria Aur\u00e9lia F.","family":"Porto","sequence":"first","affiliation":[{"name":"Universidade Federal da Bahia, Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andr\u00e9","family":"Muniz","sequence":"additional","affiliation":[{"name":"Universidade Federal da Bahia, Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jamary","family":"Oliveira 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