{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,4,4]],"date-time":"2022-04-04T06:49:04Z","timestamp":1649054944999},"reference-count":17,"publisher":"FapUNIFESP (SciELO)","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev. Soc. Bras. Med. Trop."],"published-print":{"date-parts":[[2010,12]]},"abstract":"<jats:p>INTRODU\u00c7\u00c3O: Em 1997, ap\u00f3s a realiza\u00e7\u00e3o de estudo multic\u00eantrico, duplo cego e randomizado, em nove centros de tratamento de hansen\u00edase na \u00cdndia, o Minist\u00e9rio da Sa\u00fade adotou o esquema alternativo dose \u00fanica ROM para casos de les\u00e3o \u00fanica, paucibacilar, sem nervo perif\u00e9rico afetado, \u00edndice bacilosc\u00f3pico negativo, em Centros de Refer\u00eancia da doen\u00e7a no Brasil. O estudo se prop\u00f4s a avaliar a efetividade do esquema ROM em pacientes tratados no per\u00edodo de 1997 a 1999 no Servi\u00e7o de Dermatologia da Santa Casa de Vit\u00f3ria. M\u00c9TODOS: Foram selecionados e tratados com o esquema ROM, 54 pacientes das formas indeterminada e tubercul\u00f3ide. Estes pacientes foram convocados de mar\u00e7o a outubro de 2006 para reavalia\u00e7\u00e3o cl\u00ednica. RESULTADOS: Vinte e nove pacientes avaliados (85,2%; IC95%: 70-100,4) estavam curados, cinco (14,7%; IC95%: 7,4-22,0) recidivaram e 20 pacientes n\u00e3o retornaram; por\u00e9m, n\u00e3o havia outra notifica\u00e7\u00e3o de reingresso ao tratamento no banco de dados da Secretaria Estadual de Sa\u00fade. CONCLUS\u00d5ES: O estudo evidenciou taxa de cura de 90,8% e taxa bruta de recidiva de 9,2%, ap\u00f3s per\u00edodo de sete a nove anos da dose ROM. O tratamento alternativo ROM demonstrou melhor efetividade para les\u00e3o \u00fanica menor que quatro cent\u00edmetros e aparecimento h\u00e1 menos de cinco anos.<\/jats:p>","DOI":"10.1590\/s0037-86822010000600019","type":"journal-article","created":{"date-parts":[[2010,12,20]],"date-time":"2010-12-20T01:29:04Z","timestamp":1292808544000},"page":"695-699","source":"Crossref","is-referenced-by-count":1,"title":["Avalia\u00e7\u00e3o de hansenianos tratados com esquema alternativo dose \u00fanica ROM (rifampicina, ofloxacina e minociclina), ap\u00f3s sete a nove anos"],"prefix":"10.1590","volume":"43","author":[{"given":"Lucia Martins","family":"Diniz","sequence":"first","affiliation":[{"name":"Universidade Federal do Esp\u00edrito Santo"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Melissa Daminato de Souza","family":"Catabriga","sequence":"additional","affiliation":[{"name":"Sociedade Brasileira de Dermatologia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jo\u00e3o Bas\u00edlio de","family":"Souza Filho","sequence":"additional","affiliation":[{"name":"Santa Casa de Miseric\u00f3rdia de Vit\u00f3ria"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"530","reference":[{"key":"ref1","series-title":"Hansen\u00edase","first-page":"15","volume-title":"Introdu\u00e7\u00e3o, agente etiol\u00f3gico, transmiss\u00e3o, cultura, inocula\u00e7\u00e3o, aspectos laboratoriais, patogenia e diagn\u00f3stico","author":"Talhari S","year":"2006","edition":"4\u00aa"},{"key":"ref2","first-page":"121","article-title":"Single-lesion Multicentre Trial Group. 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