{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T17:57:58Z","timestamp":1759341478957},"reference-count":10,"publisher":"FapUNIFESP (SciELO)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev. Soc. Bras. Med. Trop."],"published-print":{"date-parts":[[2011,4]]},"abstract":"<jats:p>This is a case report of a Brazilian soldier with cutaneous leishmaniasis. The lesion relapsed following two systemic treatments with meglumine antimoniate. The patient was treated with amphotericin B, which was interrupted due to poor tolerance. Following isolation of Leishmania sp., six intralesional infiltrations of meglumine antimoniate resulted in no response. Leishmania sp promastigotes were again isolated. The patient was submitted to intramuscular 4mg\/kg pentamidine. Parasites from the first and second biopsies were identified as Leishmania (Viannia) braziliensis; those isolated from the first biopsy were more sensitive to meglumine antimoniate in vitro than those isolated from the second biopsy. No relapse was observed.<\/jats:p>","DOI":"10.1590\/s0037-86822011000200026","type":"journal-article","created":{"date-parts":[[2011,5,5]],"date-time":"2011-05-05T08:14:38Z","timestamp":1304583278000},"page":"254-256","source":"Crossref","is-referenced-by-count":13,"title":["American cutaneous leishmaniasis caused by Leishmania (Viannia) braziliensis resistant to meglumine antimoniate, but with good response to pentamidine: a case report"],"prefix":"10.1590","volume":"44","author":[{"given":"Maria In\u00eas Fernandes","family":"Pimentel","sequence":"first","affiliation":[{"name":"Funda\u00e7\u00e3o Oswaldo Cruz"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cibele","family":"Baptista","sequence":"additional","affiliation":[{"name":"Funda\u00e7\u00e3o Oswaldo Cruz"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u00c9velyn Figueiredo","family":"Rubin","sequence":"additional","affiliation":[{"name":"Funda\u00e7\u00e3o Oswaldo Cruz"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u00c9rica de Camargo Ferreira e","family":"Vasconcellos","sequence":"additional","affiliation":[{"name":"Funda\u00e7\u00e3o Oswaldo Cruz"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marcelo Rosandiski","family":"Lyra","sequence":"additional","affiliation":[{"name":"Funda\u00e7\u00e3o Oswaldo Cruz"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mariza de Matos","family":"Salgueiro","sequence":"additional","affiliation":[{"name":"Funda\u00e7\u00e3o Oswaldo Cruz"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maur\u00edcio Naoto","family":"Saheki","sequence":"additional","affiliation":[{"name":"Funda\u00e7\u00e3o Oswaldo Cruz"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cl\u00e1udia Maria Valete","family":"Rosalino","sequence":"additional","affiliation":[{"name":"Funda\u00e7\u00e3o Oswaldo Cruz"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria de F\u00e1tima","family":"Madeira","sequence":"additional","affiliation":[{"name":"Funda\u00e7\u00e3o Oswaldo Cruz"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aline Fagundes da","family":"Silva","sequence":"additional","affiliation":[{"name":"Funda\u00e7\u00e3o Oswaldo Cruz"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eliame Mouta","family":"Confort","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Armando de Oliveira","family":"Schubach","sequence":"additional","affiliation":[{"name":"Funda\u00e7\u00e3o Oswaldo Cruz"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"530","reference":[{"key":"ref1","series-title":"Manual de Vigil\u00e2ncia da Leishmaniose Tegumentar Americana","year":"2010","edition":"2"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"1457","DOI":"10.1086\/515027","article-title":"Safety and efficacy of intravenous sodium stibogluconate in the treatment of leishmaniasis: recent U. S. military experience","volume":"27","author":"Aronson NE","year":"1998","journal-title":"Clin Infect Dis","ISSN":"http:\/\/id.crossref.org\/issn\/1058-4838","issn-type":"print"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"296","DOI":"10.4269\/ajtmh.1994.50.296","article-title":"A general classification of New World Leishmania using numerical zymotaxonomy","volume":"50","author":"Cupolillo E","year":"1994","journal-title":"Am J Trop Med Hyg","ISSN":"http:\/\/id.crossref.org\/issn\/0002-9637","issn-type":"print"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1590\/S0074-02762007000100012","article-title":"Activity of Brazilian and Bulgarian propolis against different species of Leishmania","volume":"102","author":"Machado GM","year":"2007","journal-title":"Mem Inst Oswaldo Cruz","ISSN":"http:\/\/id.crossref.org\/issn\/0074-0276","issn-type":"print"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1590\/S0037-86822003000500008","article-title":"Aspectos cl\u00ednicos e diagn\u00f3sticos da leishmaniose tegumentar Americana em militares simultaneamente expostos \u00e0 infec\u00e7\u00e3o na Amaz\u00f4nia","volume":"36","author":"Guerra JAO","year":"2003","journal-title":"Rev Soc Bras Med Trop","ISSN":"http:\/\/id.crossref.org\/issn\/0037-8682","issn-type":"print"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1590\/S0037-86822006000200001","article-title":"Fatores associados ao insucesso do tratamento da leishmaniose cut\u00e2nea com antimoniato de meglumina","volume":"39","author":"Rodrigues AM","year":"2006","journal-title":"Rev Soc Bras Med Trop","ISSN":"http:\/\/id.crossref.org\/issn\/0037-8682","issn-type":"print"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1097\/01.qco.0000191508.48481.f4","article-title":"Comparison of the efficacy and pharmacology of formulations of amphotericin B used in treatment of leishmaniasis","volume":"18","author":"Barratt G","year":"2005","journal-title":"Curr Op Infect Dis"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1128\/CMR.19.1.111-126.2006","article-title":"Drug resistance in leishmaniasis","volume":"19","author":"Croft SL","year":"2006","journal-title":"Clin Microbiol Rev","ISSN":"http:\/\/id.crossref.org\/issn\/0893-8512","issn-type":"print"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"688","DOI":"10.1645\/GE-1031R.1","article-title":"Sensitivity of Leishmania braziliensis promastigotes to meglumine antimoniate (glucantime) is higher than that of other Leishmania species and correlates with response to therapy in American tegumentary leishmaniasis","volume":"93","author":"Azeredo-Coutinho RB","year":"2007","journal-title":"J Parasitol","ISSN":"http:\/\/id.crossref.org\/issn\/0022-3395","issn-type":"print"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"796","DOI":"10.1046\/j.1365-4362.2002.01633.x","article-title":"Pentamidine, the drug of choice for the treatment of cutaneous leishmaniasis in Surinam","volume":"41","author":"Lai A Fat EJSK","year":"2002","journal-title":"Int J Dermatol","ISSN":"http:\/\/id.crossref.org\/issn\/0011-9059","issn-type":"print"}],"container-title":["Revista da Sociedade Brasileira de Medicina Tropical"],"original-title":[],"link":[{"URL":"http:\/\/www.scielo.br\/pdf\/rsbmt\/v44n2\/26.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,5,26]],"date-time":"2017-05-26T18:22:21Z","timestamp":1495822941000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.scielo.br\/scielo.php?script=sci_arttext&pid=S0037-86822011000200026&lng=en&tlng=en"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,4]]},"references-count":10,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2011,4]]}},"alternative-id":["S0037-86822011000200026"],"URL":"https:\/\/doi.org\/10.1590\/s0037-86822011000200026","relation":{},"ISSN":["0037-8682"],"issn-type":[{"value":"0037-8682","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,4]]}}}