{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,15]],"date-time":"2026-01-15T04:03:06Z","timestamp":1768449786555,"version":"3.49.0"},"reference-count":18,"publisher":"FapUNIFESP (SciELO)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev. Soc. Bras. Med. Trop."],"published-print":{"date-parts":[[2012,6]]},"abstract":"<jats:p>INTRODUCTION: Since 1970, lengthening of the rectosigmoid has been suspected to be a solitary manifestation of Chagas colopathy. METHODS: To test this hypothesis, opaque enema was administered on 210 seropositive and 63 seronegative patients, and radiographs in the anteroposterior and posteroanterior positions were examined blind to the serological and clinical findings. The distal colon was measured using a flexible ruler along the central axis of the image from the anus to the iliac crest. RESULTS: Dolichocolon was diagnosed in 31 (14.8%) seropositive and 3 (4.8%) seronegative patients. The mean length was 57.2 (\u00b112.2)cm in seropositive patients and 52.1 (\u00b18.8)cm in the seronegative patients (p = 0.000), that is, the distal colon in Chagas patients was, on average, 5.1cm longer. Seropositive female patients presented a mean length of 58.8 (\u00b112.3)cm, and seronegative female patients presented 53.2 (\u00b19.1)cm (p = 0.002). Seropositive male patients had a mean length of 55 (\u00b111.6)cm, and seronegative male patients had 49.9 (\u00b17.8)cm (p = 0.02). Among 191 patients without megacolon and suspected megacolon, the mean length was 56.3 (\u00b111.6)cm in seropositive individuals and 52 (\u00b18.8)cm in seronegative patients (p = 0.003). Among individuals with distal colon &gt;70cm, there were 31 Chagas patients with mean length of 77.9 (\u00b17.1)cm and three seronegative with 71.3 (\u00b11.1)cm (p = 0.000). Among 179 with distal colon &lt;70cm, seropositive individuals had a mean length of 53.6 (\u00b18.8)cm, and seronegative patients had 51.2 (\u00b17.8)cm (p = 0.059). Serological positive women had longer distal colon than men (p = 0.02), whereas the mean length were the same among seronegative individuals (p = 0.16). CONCLUSIONS: In endemic areas of Brazil Central, solitary dolichocolon is a radiological Chagas disease signal.<\/jats:p>","DOI":"10.1590\/s0037-86822012000300014","type":"journal-article","created":{"date-parts":[[2012,6,30]],"date-time":"2012-06-30T11:33:51Z","timestamp":1341056031000},"page":"353-356","source":"Crossref","is-referenced-by-count":8,"title":["Occurrence of dolichocolon without megacolon in chronic Chagas disease patients"],"prefix":"10.1590","volume":"45","author":[{"given":"Cleudson","family":"Castro","sequence":"first","affiliation":[{"name":"Universidade de Bras\u00edlia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Esperanza Bernal","family":"Hernandez","sequence":"additional","affiliation":[{"name":"Secret\u00e1ria de Sa\u00fade do Distrito Federal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joffre","family":"Rezende","sequence":"additional","affiliation":[{"name":"Universidade Federal de Goi\u00e1s; Universidade de Bras\u00edlia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aluizio","family":"Prata","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"530","reference":[{"key":"ref1","first-page":"37","article-title":"Trypanosomiase americana","volume":"8","author":"Chagas C","year":"1916","journal-title":"Forma aguda da mol\u00e9stia. Mem Inst Oswaldo Cruz"},{"key":"ref2","first-page":"75","article-title":"Viagem cientifica pelo norte da Bahia, sudoeste de Pernambuco, sul do Piauhi e de norte a sul de Goi\u00e1s","volume":"Tomo III fasc 3","author":"Neiva A","year":"1916","journal-title":"Mem Inst Oswaldo Cruz","ISSN":"https:\/\/id.crossref.org\/issn\/0074-0276","issn-type":"print"},{"key":"ref3","first-page":"117","article-title":"Historia do megaes\u00f4fago nos congressos no Brasil Central","volume":"16","author":"Porto C","year":"1970","journal-title":"Rev Goiana M\u00e9d"},{"key":"ref4","first-page":"643","article-title":"Etiologia e Patogenia do megaes\u00f4fago no Brasil","volume":"47","author":"Koeberle F","year":"1955","journal-title":"Rev Paulista Med"},{"key":"ref5","first-page":"297","article-title":"Megaes\u00f4fago por doen\u00e7a de Chagas","volume":"2","author":"Rezende JM","year":"1956","journal-title":"Rev Goiana Med","ISSN":"https:\/\/id.crossref.org\/issn\/0034-9585","issn-type":"print"},{"issue":"supl","key":"ref6","first-page":"23","article-title":"T\u00e9cnica simplificada para diagn\u00f3stico radiol\u00f3gico do megac\u00f3lon chag\u00e1sico","volume":"17","author":"Ximenes CA","year":"1984","journal-title":"Rev Soc Bras Med Trop","ISSN":"https:\/\/id.crossref.org\/issn\/0037-8682","issn-type":"print"},{"key":"ref7","series-title":"Trait\u00e9 D'anatomie humaine, 8\u00ba ed","author":"Testut L","year":"1931"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"562","DOI":"10.1590\/S0037-86822010000500018","article-title":"Estudo radiol\u00f3gico do megac\u00f3lon em \u00e1rea end\u00eamica de doen\u00e7a de Chagas","volume":"43","author":"Castro C","year":"2010","journal-title":"Rev Soc Bras Med Trop","ISSN":"https:\/\/id.crossref.org\/issn\/0037-8682","issn-type":"print"},{"issue":"supl II","key":"ref9","first-page":"73","article-title":"Estudo radiol\u00f3gico do c\u00f3lon atrav\u00e9s da t\u00e9cnica de Ximenes em \u00e1rea end\u00eamica de Chagas: preval\u00eancia de dolicoc\u00f3lon","volume":"36","author":"Hernandez EBR","year":"2003","journal-title":"Rev Soc Bras Med Trop","ISSN":"https:\/\/id.crossref.org\/issn\/0037-8682","issn-type":"print"},{"key":"ref10","series-title":"Grupo de estudos sobre a evolu\u00e7\u00e3o da doen\u00e7a de Chagas","author":"Prata AR","year":"1970"},{"key":"ref11","series-title":"Doen\u00e7a de Chagas em Bambu\u00ed Minas Gerais, Brasil: Estudo cl\u00ednico epidemiol\u00f3gico a partir da fase aguda, entre 1940 e 1982","author":"Dias JCP","year":"1982"},{"key":"ref12","first-page":"65","article-title":"Estudio del colon en pacientes chagasicos asintomaticos y sintomaticos","volume":"11","author":"Calderon C","year":"1987","journal-title":"Parasitol al Dia"},{"key":"ref13","first-page":"43","article-title":"Estudios digestivo y cardiologico simultaneos en pacientes chagasicos asintomaticos","volume":"120","author":"Calderon C","year":"1992","journal-title":"Rev Med Chile"},{"key":"ref14","author":"Rezende JM","year":"1990"},{"key":"ref15","series-title":"Estudo radiol\u00f3gico do comprimento e calibre do retosigm\u00f3ide em pacientes chag\u00e1sicos e em controles procedentes de diferentes altitudes","author":"Lopes GP.","year":"2003"},{"key":"ref16","series-title":"Contribui\u00e7\u00e3o ao estudo da anatomia patol\u00f3gica e patog\u00eanese do megac\u00f3lon chag\u00e1sico","author":"Adad SJ.","year":"1996"},{"key":"ref17","series-title":"Gastroenterology","first-page":"391","volume-title":"Developmental anomalies of the colon","volume":"II","author":"Bockus HL.","year":"1949"},{"key":"ref18","series-title":"El colon \u00edleo-pelvico en los peruanos","author":"Franco FE.","year":"1965"}],"container-title":["Revista da Sociedade Brasileira de Medicina Tropical"],"original-title":[],"link":[{"URL":"http:\/\/www.scielo.br\/pdf\/rsbmt\/v45n3\/a14v45n3.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,5,27]],"date-time":"2017-05-27T06:47:55Z","timestamp":1495867675000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.scielo.br\/scielo.php?script=sci_arttext&pid=S0037-86822012000300014&lng=en&tlng=en"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,6]]},"references-count":18,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2012,6]]}},"alternative-id":["S0037-86822012000300014"],"URL":"https:\/\/doi.org\/10.1590\/s0037-86822012000300014","relation":{},"ISSN":["0037-8682"],"issn-type":[{"value":"0037-8682","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,6]]}}}